Lan Zhang

ORCID: 0000-0002-2162-3333
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About
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Research Areas
  • Bone Tissue Engineering Materials
  • Nanoplatforms for cancer theranostics
  • Diamond and Carbon-based Materials Research
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Dental Implant Techniques and Outcomes
  • Titanium Alloys Microstructure and Properties
  • Cancer-related molecular mechanisms research
  • Electrospun Nanofibers in Biomedical Applications
  • Dental materials and restorations
  • Polymer Surface Interaction Studies
  • Orthopaedic implants and arthroplasty
  • Advanced Photocatalysis Techniques
  • Anodic Oxide Films and Nanostructures
  • Magnesium Alloys: Properties and Applications
  • Metal and Thin Film Mechanics
  • Wound Healing and Treatments
  • ZnO doping and properties
  • Microstructure and Mechanical Properties of Steels
  • MXene and MAX Phase Materials
  • Calcium Carbonate Crystallization and Inhibition
  • Advanced Surface Polishing Techniques
  • Copper-based nanomaterials and applications
  • Polymer composites and self-healing
  • Metallurgy and Material Forming

Xi'an Jiaotong University
2016-2025

Jiangnan University
2025

Sichuan University
2020-2025

Huazhong Agricultural University
2025

Renji Hospital
2024

Shanghai Jiao Tong University
2024

University of Science and Technology of China
2020-2024

Jilin University
2021-2024

Shanghai University
2021-2024

Fujian University of Traditional Chinese Medicine
2024

To endow percutaneous implants with improved skin integration and antibacterial activity, microporous TiO2 coatings doped different doses of Cu2+ (0-1.93 wt%) were directly fabricated on Ti via micro-arc oxidation (MAO). The structures investigated; the adhesion, proliferation, phenotype, differentiation extracellular collagen secretion fibroblasts, as well response Staphylococcus aureus (S. aureus), also investigated. obtained results show that all consist antase rutile, incorporation...

10.1039/c6tb00563b article EN Journal of Materials Chemistry B 2016-01-01

Ferroptosis is an iron-dependent cell death and associated with cancer therapy. Can it play a role in resistance of postoperative infection implants, especially extracellular supplement Fe ions non-cytotoxic dose? To answer this, "nanoswords" Fe-doped titanite are fabricated on Ti implant surface to resist bacterial invasion by synergistic action ferroptosis-like bacteria killing, proton disturbance, physical puncture. The related antibiosis mechanism explored atomic force microscopy genome...

10.1021/acsnano.2c10960 article EN ACS Nano 2023-01-20

Abstract Methicillin‐resistant Staphylococcus aureus (MRSA) is threatening human health due to its resistance multiple antibiotics. Excessive copper (Cu) ions target the lipoylated proteins of tricarboxylic acid cycle cancer cells, inducing proteotoxic stress and their cuproptosis death. Whether plays a part in killing MRSA by low‐dose supplement Cu remains be explored. Herein, Cu‐doped hydroxyapatite nanorods (PC) are prepared on polyetheretherketone (PEEK) resist infection improve PEEK...

10.1002/adfm.202308197 article EN Advanced Functional Materials 2023-09-15

Abstract Electron spinning polarization has garnered increased attention for its potential to enhance device properties. However, application in life health, specifically anti‐infection and tissue repair, remains under‐explored. In this study, a ferromagnetic heterojunction CF (Fe 3 O 4 /TiO 2 ) is constructed with spin‐polarized electrons, demonstrating efficient antibiosis performance ultrasound (US) assistance. The antibacterial mechanism elucidated as follows: metallic states of Fe...

10.1002/adfm.202401795 article EN Advanced Functional Materials 2024-04-01

Polypyrrole nanowires have been electrosynthesized by direct oxidation of 0.1 mol l−1 pyrrole in a medium 75% isopropyl alcohol + 20% boron trifluoride diethyl etherate 5% poly (ethylene glycol) (by volume) using porous alumina membranes as the templates. The as-prepared had smooth surface and uniform diameter were arranged an orderly manner high density. conductivity single nanowire was measured four-electrode technique to be 23.4 S cm−1 at room temperature. field emission devices based on...

10.1088/0957-4484/17/14/017 article EN Nanotechnology 2006-06-20

Strontium-doped hydroxyapatite (Ca9Sr1(PO4)6(OH)2, Sr1-HA) nanorods with different lateral spacing (e.g., interrod spacing) values (67.3 ± 3.8, 95.7 4.2, and 136.8 8.7 nm) nanogranulates were grown on microarc-oxidized microporous TiO2, respectively, to form multilayer coatings. The coatings reveal two kinds of micro/nanoscaled hierarchical surfaces a similar microscale roughness, e.g., nanogranulated 2D pattern nanorod-shaped 3D in nanotopography. When hFOB1.19 cells are employed, the...

10.1021/am401339n article EN ACS Applied Materials & Interfaces 2013-05-13

10.1016/j.jmst.2016.01.008 article EN Journal of Material Science and Technology 2016-01-06

Abstract The SiC/Al 4 SiC composites with the improved mechanical properties and thermal conductivity were fabricated by in-situ reaction of polycarbosilane (PCS) Al powders using spark plasma sintering. addition 5 wt% yttrium (Y) sintering additive was useful to obtain fully dense samples after at a relatively low temperature 1650 °C, due formation liquid phase during average particle size formed ~300 nm. fracture toughness (4.9 MP·m 1/2 ), Vickers hardness (16.3 GPa), (15.8 W/(m·K))...

10.1007/s40145-020-0359-8 article EN cc-by Journal of Advanced Ceramics 2020-04-01

An ideal intraosseous transcutaneous implant should form a tight seal with soft tissue, besides requirement of osseointegration at the bone-fixed position. Si substituted hydroxyapatite (Si-HA) nanorods releasing ion and simulating nanotopography natural tissue were designed on Ti to enhance fibroblast response

10.1016/j.bioactmat.2020.01.001 article EN cc-by-nc-nd Bioactive Materials 2020-01-25

Titanium is widely utilized for manufacturing medical implants due to its inherent mechanical strength and biocompatibility. Recent studies have focused on developing coatings impart unique properties Ti implants, such as antimicrobial behavior, enhanced cell adhesion, osteointegration. Ca- Si-based ceramic (CS) can enhance bone integration through the release of Ca Si ions. However, high degradation rates CS ceramics create a basic environment that reduces viability. Polymeric or...

10.1021/acsami.1c04895 article EN ACS Applied Materials & Interfaces 2021-06-10

Abstract Bone defects are seriously threatening the health of orthopedics patients and it is difficult for implants to accelerate bone regeneration without using growth factors. Herein, a fast photothermal ion therapeutic strategy developed based on bandgap engineering nanostructured TiO 2 through (Si/P)‐dual elemental doping by micro‐arc oxidation treatment titanium implants. The can tune surface structure decreasing broadening valence band simultaneously, which confirmed density functional...

10.1002/adhm.202200998 article EN Advanced Healthcare Materials 2022-09-06

Abstract Percutaneous implants may experience infection for several times during their servicing periods. They need antibacterial activity and durability to reduce recurrent cytocompatibility reconstruct biosealing. A novel photoresponse bio‐heterojunction (PCT) is developed herein. It consists of TiO 2 nanotubes loaded with CuS nanoparticles wrapped polydopamine (PDA) layer. In PCT, a built‐in electric field directing from then PDA formed, near‐infrared (NIR) irradiation, it drives...

10.1002/smll.202206265 article EN Small 2022-12-05
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