A5017893069- Urological Disorders and Treatments
- Urinary Bladder and Prostate Research
- Pediatric Urology and Nephrology Studies
- Sexual Differentiation and Disorders
- Drug Transport and Resistance Mechanisms
- Urinary and Genital Oncology Studies
- Testicular diseases and treatments
- Gastroesophageal reflux and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Urologic and reproductive health conditions
- Simulation-Based Education in Healthcare
- Kidney Stones and Urolithiasis Treatments
- Surgical Simulation and Training
- Ureteral procedures and complications
- Liver Disease Diagnosis and Treatment
- Sympathectomy and Hyperhidrosis Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Urinary Tract Infections Management
- Anatomy and Medical Technology
- Liver Disease and Transplantation
- Pelvic floor disorders treatments
- Porphyrin Metabolism and Disorders
- Congenital Anomalies and Fetal Surgery
- Genetic and Kidney Cyst Diseases
Hospices Civils de Lyon
2023-2025
Hôpital Femme Mère Enfant
2023-2025
Inserm
2019-2025
Université Claude Bernard Lyon 1
2025
Erasmus University Rotterdam
2025
Hôpital Robert-Debré
2020-2024
Université Paris Cité
2020-2024
Assistance Publique – Hôpitaux de Paris
2020-2024
Fondation Lenval
2024
Université Paris-Saclay
2020-2022
To evaluate long-term outcomes and predictive factors of urinary continence (UC) fecal (FC) after surgery for classic bladder exstrophy (CBE) using validated questionnaires. This study is part the QUALEXSTRO study, a retrospective, observational, single-centre cohort assessing through questionnaires UC, FC, sexuality, fertility, quality life in patients treated CBE, who were aged at least 15 years evaluation. Herein, UC FC assessed International Consultation on Incontinence...
Objective We explored the hypothesis that TGR5, bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects liver against BA overload through regulation of epithelium permeability. Design Experiments were performed under basal and TGR5 agonist treatment. In vitro transepithelial electric resistance (TER) FITC-dextran diffusion measured different cell lines. vivo was injected gallbladder (GB) lumen traced plasma. Tight junction proteins TGR5-induced...
As the composition of bile acid (BA) pool has a major impact on liver pathophysiology, we studied its regulation by BA receptor Takeda G protein coupled (TGR5), which promotes hepatoprotection against overload. Wild-type, total and hepatocyte-specific TGR5-knockout, TGR5-overexpressing mice were used in: partial (66%) 89% extended hepatectomies (EHs) upon normal, ursodeoxycholic (UDCA)- or cholestyramine (CT)-enriched diet, duct ligation (BDL), cholic (CA)-enriched TGR5 agonist (RO)...
Abstract During liver repair after injury, bile secretion has to be tightly modulated in order preserve parenchyma from acid (BA)‐induced injury. The mechanisms allowing the maintain biliary homeostasis during injury are not completely understood. Besides their historical role lipid digestion, acids (BA) and receptors constitute a signalling network with multiple impacts on repair, both stimulating regeneration protecting BA overload. signal through nuclear (mainly Farnesoid X Receptor, FXR)...
Abstract Bile acids (BA) are key for liver regeneration and injury. This study aims at analyzing the changes in BA pool induced by ischemia-reperfusion (IRI) investigates impact of hypothermic oxygenated perfusion (HOPE) on compared to static cold storage (SCS). In a porcine model IRI, grafts underwent 30 min asystolic warm ischemia followed 6 h SCS (n = 6) ± 2 HOPE ex-situ reperfusion. The bile samples was analyzed with liquid chromatography coupled tandem mass spectrometry. We identified...
<title>Abstract</title> <italic>Introduction</italic>: Mastering paediatric laparoscopic surgery competency (PLSC) is technically challenging. The present study aimed to determine whether the inter-academic PLSC degree (IAD_PLSC) practical training program enables trainees improve their skills. <italic>Methods</italic>: This retrospective included enrolled in IAD_PLSC 2021 and 2022 which two separate 15 hour-sessions. Trainees practiced perform intracorporeal knots (ILK) using 5- 3-mm...