D. Demède

ORCID: 0000-0003-4770-8535
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About
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Research Areas
  • Urological Disorders and Treatments
  • Pediatric Urology and Nephrology Studies
  • Urologic and reproductive health conditions
  • Urinary Bladder and Prostate Research
  • Kidney Stones and Urolithiasis Treatments
  • Urinary and Genital Oncology Studies
  • Urinary Tract Infections Management
  • Sexual Differentiation and Disorders
  • Organ Transplantation Techniques and Outcomes
  • Ureteral procedures and complications
  • Biomedical Research and Pathophysiology
  • Pelvic floor disorders treatments
  • Genital Health and Disease
  • Dialysis and Renal Disease Management
  • Renal Transplantation Outcomes and Treatments
  • Metabolism and Genetic Disorders
  • Pregnancy and Medication Impact
  • Vascular anomalies and interventions
  • Organ Donation and Transplantation
  • Renal Diseases and Glomerulopathies
  • Sympathectomy and Hyperhidrosis Treatments
  • Bladder and Urothelial Cancer Treatments
  • Dermatological and Skeletal Disorders
  • Spinal Dysraphism and Malformations
  • Gastroesophageal reflux and treatments

Hospices Civils de Lyon
2015-2025

Hôpital Femme Mère Enfant
2016-2025

Hôpital Lyon Sud
2021

Hôpital Mère-Enfant
2009-2019

Université Claude Bernard Lyon 1
2008-2019

Université de Lyon
2012

Centre Hospitalier Le Vinatier
2010

Hôpital Debrousse
2006-2008

To evaluate long-term outcomes and predictive factors of urinary continence (UC) fecal (FC) after surgery for classic bladder exstrophy (CBE) using validated questionnaires. This study is part the QUALEXSTRO study, a retrospective, observational, single-centre cohort assessing through questionnaires UC, FC, sexuality, fertility, quality life in patients treated CBE, who were aged at least 15 years evaluation. Herein, UC FC assessed International Consultation on Incontinence...

10.1111/bju.16680 article EN cc-by-nc-nd BJU International 2025-02-26

Improving the management of neonatal diseases and prevention chronic in adulthood requires a better comprehension complex maturational processes associated with newborns' development. Urine-based metabolomic studies play promising role fields pediatrics neonatology, relying on simple noninvasive collection procedures while integrating variety factors such as genotype, nutritional state, lifestyle, diseases. Here, we investigate influence age, weight, height, gender urine metabolome during...

10.1021/acs.jproteome.7b00421 article EN publisher-specific-oa Journal of Proteome Research 2017-08-09
Bénédicte Buffin‐Meyer Julie Klein Loes F.M. van der Zanden Elena Levtchenko Panagiotis Moulos and 95 more Nadia Lounis F. Conte-Auriol An Hindryckx Elke Wühl Nicola Persico Dick Oepkes Michiel F. Schreuder Marcin Tkaczyk Gema Ariceta Magdalena Fossum Paloma Parvex Wout Feitz Lars Henning Olsen Giovanni Montini Stéphane Decramer Joost P. Schanstra An Hindryckx Luc De Catte Christophe Vayssieres Agnès Sartor Marion Groussolles Christelle Plard Paul Guerby L. Connan Mathieu Morin Elizabeth L. Simon Jean Bréaud A.‐H. Saliou L de Parscau Nadine Jay I. Germouty G. Le Bouar Amélie Ryckewaert Marie-Christine Manca-Pellissier Thierry Merrot Hélène Laurichesse Denis Gallot Lucie Bessenay Laurent Bidat P. Boize Norbert Winer Emma Allain-Launey Claudine Le Vaillant Fabienne Prieur Marie‐Pierre Lavocat F. Coatleven Eric Debromez Jérôme Harembat Brigitte Llanas R. Favre R. Moog Ariane Zaloszyc J. Massardier D. Demède F. Perrotin Sylvie Cloarec Valérie Vequeau‐Goua Emmanuelle Descombes Pierre Boulot Denis Morin F. Fuchs Julie Tenenbaum Y. Ville Thomas Blanc Laurence Heidet Anne Paris E. Dobremez Marie-Françoise Froute J. Gondry Charles Muszynski Élodie Haraux Fabienne Lobelle Julien Chevreau Jonathan Rosenblatt V. Baudoin Georges Deschênes Virginie Guigue Florence Amblard Guylhène Bourdat-Michel Elke Wühl Franz Schaefer Michael Elsässer Nicola Persico Federica Rossi Gianantonio Manzoni Erika Adalgisa De Marco Giovanni Montini Valentina Capone Leonardo Caforio Antonio Zaccara Michele Innocenzi Pietro Bagolan Nicola Capozza Marco Castagnetti Mariangela Mancini

Posterior urethral valves (PUV) account for 17% of paediatric end-stage renal disease. A major issue in the management PUV is prenatal prediction postnatal function. Fetal ultrasound and fetal urine biochemistry are currently employed this prediction, but clearly lack precision. We previously developed a peptide signature that predicted utero with high precision function fetuses PUV. describe here objectives design prospective international multicentre ANTENATAL (multicentre validation...

10.1093/ckj/sfz107 article EN Clinical Kidney Journal 2019-07-26

Many classifications of hypospadias have been published, mainly based on the position ectopic meatus, which is an insufficient criterion to define severity this malformation. What really marks proximal landmark malformation level division corpus spongiosum, always meatus. In article, we will focus most severe forms include those with a spongiosum (below midshaft), important chordee and poor development ventral radius, reflecting marked hypovirilization genital tubercle, cripple resulting...

10.4103/0970-1591.40621 article EN cc-by-nc-sa Indian Journal of Urology 2008-01-01

We compared the prognostic value of anteroposterior intrasinus diameter renal pelvis, urinary tract dilatation and Society for Fetal Urology grading system in children with prenatally diagnosed unilateral dilatation.All newborns dilatation, normal bladder 10 mm or greater on first postnatal ultrasonography were prospectively enrolled from January 2011 to February 2015. Indications surgery recurrent febrile infections and/or decrease relative function more than 10% serial isotope studies...

10.1016/j.juro.2016.11.103 article EN The Journal of Urology 2016-12-01

Abstract Aim Our aim was to look at the technical, ethical and global issues related neonatal dialysis. Methods We performed a PubMed research on manuscripts published from March 2010 2020 retrospectively reviewed all neonates who received dialysis in our French paediatric intensive care units April 2009 2019. Results Dialysis is with pre‐existing renal diseases, acute kidney injuries or inborn errors of metabolism. It required 0.5%‐1% admitted units. Peritoneal extracorporeal blood...

10.1111/apa.15539 article EN Acta Paediatrica 2020-08-16

Abstract Renal pelvis dilatation (RPD) is diagnosed in utero on prenatal ultrasonography (US) and can resolve spontaneously. However, isolated RPD also reflect ureteropelvic junction obstruction (UPJO), which requires surgical treatment to prevent progressive renal deterioration. The diagnosis of UPJO only be confirmed after birth with repeat US isotope studies. 1 H Nuclear Magnetic Resonance spectroscopy (NMR) was performed urine newborns prenatally unilateral healthy controls identify...

10.1038/s41598-022-17664-4 article EN cc-by Scientific Reports 2022-08-04

Disorders of Sex Development (DSD) remain a fascinating challenge for the paediatricians, endocrinologists, biologists, psychiatrists, geneticists, radiologists, surgeons and whole society. This article aims at highlighting current controversies questions met with genital reconstruction in children born abnormal genitalia. The main techniques masculinization feminization are reviewed their progress problems. tools decision used to assign gender some newborns complex DSD discussed showing...

10.4321/s0004-06142010000700003 article EN cc-by-nc Archivos Españoles de Urología 2010-09-01

Isolated fallopian tube torsion (IFTT) is very rare gynecological emergency in pediatric population. Our objective to assess treatment options and discuss outcome of a cohort IFTT with focus on the association between hydrosalpinx (HSX). A retrospective review was conducted. Pediatric patients operated same center were included. Seventeen girls (aged: 11-16 years) managed for acute abdominal pain 2008 2018, intraoperative diagnosis IFTT. All underwent laparoscopic exploration,...

10.1097/pec.0000000000003209 article EN Pediatric Emergency Care 2024-05-14

Abstract RT x remains challenging in children under 3 years of age. This single‐center study reviewed the medical records <3 transplanted since 1987 (N = 32, Group 1). They were matched for donor type and period with aged 3‐13 2) 13‐18 3). There no between‐group significant differences regarding distributions gender, primary renal disease, proportion dialysis before x, growth ( SDS ). Compared to Groups 2 3, 1 had more peritoneal dialyses P < .001), EBV mismatches .04), longer warm...

10.1111/petr.13116 article EN Pediatric Transplantation 2018-01-17
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