A5062437132- Prenatal Screening and Diagnostics
- Congenital Diaphragmatic Hernia Studies
- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Congenital Anomalies and Fetal Surgery
- Fetal and Pediatric Neurological Disorders
- Parvovirus B19 Infection Studies
- Medical and Health Sciences Research
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- Urinary Tract Infections Management
- Cardiovascular Issues in Pregnancy
- Assisted Reproductive Technology and Twin Pregnancy
- Neonatal Health and Biochemistry
- Congenital Heart Disease Studies
- Cleft Lip and Palate Research
- Tracheal and airway disorders
- Intestinal Malrotation and Obstruction Disorders
- Tumors and Oncological Cases
- Face Recognition and Perception
- Kidney Stones and Urolithiasis Treatments
- Intensive Care Unit Cognitive Disorders
- Cardiac pacing and defibrillation studies
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
Hôpital Robert-Debré
2016-2025
Assistance Publique – Hôpitaux de Paris
2014-2025
Fédération française de cardiologie
2024
Université Paris Cité
2010-2024
Université Sorbonne Paris Nord
2024
Ben-Gurion University of the Negev
2016-2022
Délégation Paris 7
2020
Hudson Institute
2018
John Wiley & Sons (United Kingdom)
2018
The Technological College of Beer Sheva
2016
The Red List of Threatened Species, published by the International Union for Conservation Nature (IUCN), is a crucial tool conservation decision-making. However, despite substantial effort, numerous species remain unassessed or have insufficient data available to be assigned extinction risk category. Moreover, Listing process subject various sources uncertainty and bias. development robust automated assessment methods could serve as an efficient highly useful accelerate offer provisional...
Genetic primary microcephaly (PM) is a defect in early brain development leading to congenital microcephaly, mostly recessively inherited, and mild-to-moderate intellectual disability. PM has been largely elucidated, thanks exome genome sequencing. However, radial microbrain, the most severe form of genetic or micrencephaly described 1980s, which leads lethality very handicap, remains without molecular diagnosis. We sought identify cause microbrain by analyzing genotype children/adults...
To assess the value of fetal urine biochemistry before 23 weeks gestation in cases lower urinary tract obstruction (LUTO) to refine prognosis and select potential candidates for in-utero intervention.This was a retrospective study including 72 LUTO with sampled assayed total protein, β-2-microglobulin, sodium, chloride, calcium, phosphorus, glucose gamma-glutamyl transpeptidase (GGTP). Two groups were defined according renal outcome: 1) bilateral dysplasia on histological examination or...
ABSTRACT Objective Diffusion‐weighted magnetic resonance imaging (DWI) is a sensitive method for assessing brain maturation and detecting lesions, providing apparent diffusion coefficient (ADC) values as measure of water diffusion. Abnormal ADC are seen in ischemic such those associated with acute or chronic hypoxia. The aim this study was to assess whether the fetal were different fetuses severe intrauterine growth restriction (IUGR) compared normal controls. Methods Brain (MRI) single‐shot...
Multivoxel pattern analysis (MVPA) has gained enormous popularity in the neuroimaging community over past few years. At group level, most MVPA studies adopt an "information based" approach which sign of effect individual subjects is discarded and a non-directional summary statistic carried to second level. This contrast directional "activation typical univariate level analysis, both signal magnitude are taken into account. The transition from examining effects one voxel at time vs. several...
Posterior urethral valves (PUV) account for 17% of paediatric end-stage renal disease. A major issue in the management PUV is prenatal prediction postnatal function. Fetal ultrasound and fetal urine biochemistry are currently employed this prediction, but clearly lack precision. We previously developed a peptide signature that predicted utero with high precision function fetuses PUV. describe here objectives design prospective international multicentre ANTENATAL (multicentre validation...
To evaluate the ability to confidently identify intracranial translucency (IT) in a clinical practice and following specific training of 10 operators.Two experienced observers reviewed 11-13-week nuchal (NT) images for IT visibility (1) series 50 randomly selected obtained by skilled operators certified Collège Français d'Echographie Foetale (CFEF) (retrospective analysis) (2) 315 different visualization (prospective analysis). We calculated proportions which was deemed visible agreement...
Because the literature on predictive value of fetal urinalysis is controversial in fetuses with lower urinary tract obstruction, we determined best model urine biochemical markers correlated long-term postnatal renal function based glomerular filtration rate (GFR).This retrospective study concerned 89 obstruction and their after 10 years age. We (total protein, β2-microglobulin, sodium, chloride, glucose, calcium, phosphorus) GFR at to 30 age patients posterior urethral valves. defined five...
ABSTRACT Objectives To assess prenatal changes in the volume of congenital pulmonary malformations (CPM) and examine whether these differ lesions that appear cystic on ultrasound compared with hyperechoic lesions, to study relationship between CPM risk fetal compression. Methods We conducted a nationally representative, multicenter, prospective cohort study, which included 579 examinations 176 pregnant women diagnosis CPM, March 2015 November 2016. Several were performed delivery, including...
Abstract Objective In singleton pregnancies, the use of cell‐free DNA (cfDNA) analysis as a screening test for common fetal trisomies has spread worldwide though we still lack sufficient data its in triplet pregnancies. The objective this study is to assess performance cfDNA testing detecting aneuploidies pregnancies first‐tier test. Method We performed retrospective cohort including from pregnant women with pregnancy who underwent between May 1, 2017, and January 15, 2020. was obtained by...
Abstract Objective To investigate the contribution of volume contrast imaging (VCI) in assessing fetal uterus normally developed female fetuses. Methods The pelvis 38 normal fetuses was examined at 20–22 and 32–34 weeks' gestation using both conventional two‐dimensional (2D) ultrasound VCI on same transverse or oblique longitudinal view pelvis. Two experienced sonographers evaluated ability techniques to image uterus. Results were compared by kappa index evaluate interobserver variability. A...
PURPOSE: To compare breath-hold T1-weighted magnetization-prepared gradient-echo (MP-GRE) imaging with conventional T2-weighted spin-echo (SE) in evaluation of focal liver disease. MATERIALS AND METHODS: Images 68 patients evaluated for disease were reviewed. Five sets images analyzed: axial, sagittal, and coronal MP-GRE images, axial SE a compilation (three-plane) images. Lesion signal intensity (SI) difference-to-noise (SD/N) ratios calculated. RESULTS: Lesions detected, localized,...
<i>Objective:</i> To assess the complications of third-trimester amniocentesis for fetal karyotyping in women unwilling to accept loss risks second-trimester amniocentesis. <i>Methods:</i> Retrospective study singleton pregnancies that underwent a karyotyping. 150 complete charts between 1998 and 2005 were reviewed. <i>Results:</i> The indications were: isolated abnormal biochemical markers (n = 57), maternal age >38 years 46), integrated risk (maternal...
The long-term morbidity associated with isolated left-sided congenital diaphragmatic hernia (CDH) has been described previously. However, antenatal criteria impacting gastrointestinal (GIM) are not yet defined. objective of this study was to evaluate the effect fetal stomach position on risk GIM at 2 years age in children CDH.This a retrospective, observational multicenter cohort data obtained from January 2010 2014, that included patients whose fetus had CDH, or without endoscopic tracheal...
Neonatal hyperthyroidism may be caused by a permanent non-autoimmune genetic disorder or, more frequently, maternally transmitted high serum TRAb levels. Variable thyroid dysfunction observed in this second context. We aimed to evaluate the prevalence of neonatal and different types function neonates with risk due maternal Graves' disease (GD).This observational cohort study included all identified database single academic pediatric care center, over period 13 years, as having or an...
A 29-year-old primigravida presented with a spontaneous miscarriage at 8 weeks of gestation. There was no consanguinity in the family. Aspiration performed. Pathological examination showed immature villi numerous slightly yellow intracytoplasmic inclusions within early implantation stage cytotrophoblastic cells. Inclusions were periodic acid–Schiff and Alcian blue positive partially amylase. Diagnosis Glycogen storage disease type IV (GSD IV) made. Genetic analysis glycogen branching enzyme...
To measure prospectively apparent diffusion coefficient (ADC) values between 28 and 32 weeks of gestation in different cerebral territories fetuses with estimated fetal weight (EFW) ≤ 5th centile, analyze their association adverse perinatal outcome.This was a prospective study involving six tertiary-level centers. In the period 22 November 2016 to 11 September 2017, we included singleton, small-for-gestational-age (SGA) EFW percentile, gestation, regardless umbilical artery Doppler maternal...