A5037774924- Genetic diversity and population structure
- Chromosomal and Genetic Variations
- Genomics and Phylogenetic Studies
- Genetic and phenotypic traits in livestock
- Plant nutrient uptake and metabolism
- Animal Behavior and Reproduction
- Genetic Mapping and Diversity in Plants and Animals
- Species Distribution and Climate Change
- Evolution and Genetic Dynamics
- Animal Disease Management and Epidemiology
- Bird parasitology and diseases
- Olfactory and Sensory Function Studies
- Plant Virus Research Studies
- Plant Reproductive Biology
- Genetic and Environmental Crop Studies
- Microbial infections and disease research
- Yersinia bacterium, plague, ectoparasites research
- Vector-borne infectious diseases
- Avian ecology and behavior
- T-cell and B-cell Immunology
- Ecology and Vegetation Dynamics Studies
- Circadian rhythm and melatonin
- Neurobiology and Insect Physiology Research
- Plant Disease Resistance and Genetics
- Virology and Viral Diseases
Charles University
2020-2025
Czech Academy of Sciences, Biology Centre
2016-2025
Institute of Parasitology
2020-2025
University of South Bohemia in České Budějovice
2016-2024
Sewanee: The University of the South
2023
Czech Academy of Sciences
2020
Parallel adaptation provides valuable insight into the predictability of evolutionary change through replicated natural experiments. A steadily increasing number studies have demonstrated genomic parallelism, yet magnitude this parallelism varies depending on whether populations, species, or genera are compared. This led us to hypothesize that scales with genetic divergence between lineages, but is case and underlying processes remain unknown. Here, we resequenced seven parallel lineages two
ABSTRACT Restricted range size brings about noteworthy genetic consequences that may affect the viability of a population and eventually its extinction. Particularly, question if an increase in inbreeding can avert accumulation load via purging is hotly debated conservation field. Insular populations with limited sizes represent ideal setup for relating to these factors. Leveraging set eight differently sized Galápagos mockingbirds ( Mimus ), we investigated how island shaped effective N e...
Relative contributions of pre-existing vs de novo genomic variation to adaptation are poorly understood, especially in polyploid organisms. We assess this high resolution using autotetraploid Arabidopsis arenosa, which repeatedly adapted toxic serpentine soils that exhibit skewed elemental profiles. Leveraging a fivefold replicated invasion, we selection on SNPs and structural variants (TEs) 78 resequenced individuals discover significant parallelism candidate genes involved ion homeostasis....
Abstract Genetic variation underpins evolutionary change, but accumulation of slightly deleterious mutations also increases mutation load. There are multiple factors affecting the extent load such as population size and breeding system, yet other potential determinants remain unexplored. A common macromutation, whole-genome duplication (WGD) occurs broadly across Eukaryotes, we lack a clear understanding how WGD impacts neutral selective processes within population. Using forward simulations...
Whole-genome duplication (WGD), a widespread macromutation across eukaryotes, is predicted to affect the tempo and modes of evolutionary processes. By theory, additional set(s) chromosomes present in polyploid organisms may reduce efficiency selection while, simultaneously, increasing heterozygosity buffering deleterious mutations. Despite theoretical significance WGD, empirical genomic evidence from natural populations scarce direct comparisons footprints between autopolyploids closely...
Polyploidy, the result of whole genome duplication (WGD), is widespread across tree life and often associated with speciation adaptability. It thought that adaptation in autopolyploids (within-species polyploids) may be facilitated by increased access to genetic variation. This variation sourced from gene flow sister diploids new other tetraploid lineages, as well mutational targets provided doubled DNA content. Here, we deconstruct detail origins haplotypes displaying strongest selection...
The extracellular subunit of the major histocompatibility complex MHCIIβ plays an important role in recognition pathogens and initiation adaptive immune response vertebrates. It is widely accepted that pathogen-mediated selection combination with neutral micro-evolutionary forces (e.g. genetic drift) shape diversity MHCIIβ, but it has proved difficult to determine relative effects these forces. We evaluated effect drift balancing on 12 small populations Galápagos mockingbirds belonging four...
Abstract Polyploidy, the result of whole genome duplication (WGD), is widespread across tree life and often associated with speciation or adaptability. It thought that adaptation in autopolyploids (within-species polyploids) may be facilitated by increased access to genetic variation. This variation sourced from gene flow sister diploids new other tetraploid lineages, as well mutational targets provided doubled DNA content. Here we deconstruct origins haplotype blocks displaying strongest...
Abstract Adaptation to varying environments, leading population divergence, is one of the key processes natural selection. However, its effectiveness amidst ongoing gene flow remains controversial. Our study explores this phenomenon by focusing on a tapeworm parasite ( Ligula intestinalis ), which capable parasitising wide spectrum fish species, overcoming their immunological defence and having highly pathogenic impact. We analysed genetic structure, degree flow, level genomic divergence...
Abstract The interactions of evolutionary forces are difficult to analyse in free‐living populations. However, when properly understood, they provide valuable insights into biology and conservation genetics. This is particularly important for the interplay genetic drift natural selection immune genes that confer resistance disease. Galápagos Islands inhabited by four closely related species mockingbirds ( Mimus spp.). We used 12 different‐sized populations one population their continental...
Abstract Parallel adaptation provides valuable insight into the predictability of evolutionary change through replicated natural experiments. A steadily increasing number studies have demonstrated genomic parallelism, yet magnitude this parallelism varies depending on whether populations, species or genera are compared. This led us to hypothesize that scales with genetic divergence between lineages, but is case and underlying processes remain unknown. Here, we resequenced seven parallel...
The Eastern European vole ( Microtusmystacinus ) is an arvicoline rodent distributed across northern and eastern Europe, the Balkans, Turkey, Armenia, NW N Iran, Russia as far east Tobol River in W Siberia, Kazakhstan. We present a novel records from Kazakhstan (the village of Dzhambul – 49°14'21.3"N, 86°18'29.9"E Sekisovka 50°21'9.18"N, 82°35'46.5"E) based on mtDNA we discuss implications this findings biogeography populations. Marine Isotope Stage 11 considered important period for...
Abstract Very recently, an interesting phenomenon was described in the common vole; vole parents with similar locomotor ability produced significantly larger litters. Positive assortative mating is a tendency to prefer individuals phenotypes. We tested whether this also applies smell similarity. Odour preference T-maze, where each female presented two male odours, i.e. shavings together feces and urine from home boxes. After established, either paired preferred (chosen) or non-preferred...
Abstract Relative contributions of pre-existing vs de novo genomic variation to adaptation are poorly understood, especially in polyploid organisms, which maintain increased variation. We assess this high resolution using autotetraploid Arabidopsis arenosa , repeatedly adapted toxic serpentine soils that exhibit skewed elemental profiles. Leveraging a fivefold replicated invasion, we selection on SNPs and structural variants (TEs) 78 resequenced individuals discovered substantial parallelism...
Abstract Very recently, an interesting phenomenon was described in the common vole; vole parents with similar locomotor ability produced significantly larger litters. Positive assortative mating is a tendency to prefer individuals phenotypes. We tested whether this also applies smell similarity. Odor preference T-maze, where each female presented two male odors, i. e. shavings together feces and urine from home boxes. After established, either paired preferred (chosen) or non-preferred...