A5038091757- Cutaneous Melanoma Detection and Management
- Digital Imaging in Medicine
- T-cell and B-cell Immunology
- Social Media in Health Education
- Telemedicine and Telehealth Implementation
- Immune Cell Function and Interaction
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Dermatology and Skin Diseases
- Contact Dermatitis and Allergies
- Systemic Lupus Erythematosus Research
- Acne and Rosacea Treatments and Effects
- Nonmelanoma Skin Cancer Studies
- Inflammatory Myopathies and Dermatomyositis
- Allergic Rhinitis and Sensitization
- Dermatological and Skeletal Disorders
- Pharmaceutical industry and healthcare
- Urticaria and Related Conditions
- Healthcare Systems and Technology
- Nail Diseases and Treatments
- Stoma care and complications
- Melanoma and MAPK Pathways
- Clinical practice guidelines implementation
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Fungal Plant Pathogen Control
Duke University Health System
2018-2024
Duke University
2016-2024
Duke University Hospital
2017-2024
Duke Medical Center
2017-2023
Rutgers, The State University of New Jersey
2013
University of Dental Medicine
2013
University of North Carolina at Chapel Hill
2006-2010
Report of a Case | The patient first presented in 2008 at age 41 years with 3-year history diffuse asymptomatic ashygray dermatosis.The lesions initially appeared erythematous nonscaling palpable borders, and within 3 months it had evolved to ashy-gray patches.There were no identifiable triggers or associated family history.Cutaneous examination revealed patches varying sizes symmetrically distributed throughout the body (Figure ,A), while mucosa, palms, soles, nails spared.Laboratory...
Patient-submitted images vary considerably in quality and usefulness. Studies that characterize patient-submitted a real-life setting are lacking.To evaluate the perceived usefulness of as determined by dermatologists agreement their responses.This survey study included patient submitted to Department Dermatology at Duke University (Durham, North Carolina) between August 1, 2018, December 31, 2019. From total pool 1200 images, 10 evaluated 200 or 400 each, with every image being 3...
The image quality received for clinical evaluation is often suboptimal. goal to develop an analysis tool assess patient- and primary care physician–derived images using deep learning model. Dataset included from August 21, 2018 June 30, 2022 with 4 unique labels. VGG16 model was fine tuned input data, optimal threshold determined by Youden's index. Ordinal labels were transformed binary a majority vote because distinguishes between 2 categories (good vs bad). At of 0.587, area under the...
Abstract EBV is associated with systemic lupus erythematosus (SLE), but how it might contribute to the etiology not clear. Since EBV-encoded latent membrane protein 2A (LMP2A) interferes normal B cell differentiation and function, we sought determine its effect on tolerance. Mice transgenic for both LMP2A Ig transgene 2-12H specific ribonucleoprotein Smith (Sm), a target of immune system in SLE, develop spontaneous anti-Sm response. allows cells overcome regulatory checkpoint at early...
Abstract Background Teledermatology (TD) is an evidence-based practice that may increase access to dermatologic care. We sought use the Exploration, Preparation, Implementation, and Sustainment (EPIS) Reach, Efficacy, Adoption, Maintenance (RE-AIM) frameworks evaluate implementation of TD at Duke. Methods The EPIS RE-AIM were deployed design implement a program leveraged strengths Duke University Health System addressed previously reported barriers store-and-forward synchronous models. In...
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Calcinosis cutis is the deposition of calcium salts in skin and subcutaneous tissue, manifesting as variably shaped papules, nodules, plaques that can substantially impair quality life. The pathophysiology calcinosis involves dysregulation proinflammatory cytokines, leukocytes, other components innate immune system. In some conditions associated with cutis, elevated serum calcium, phosphate, vitamin D may also perturb immunity. mechanisms by which these lead to cutaneous calcification likely...
Patient-submitted images can be helpful for medical decision-making when requested by dermatologists. However, unsolicited photographs may burden dermatologists and have variable clinical usefulness. In this survey study, we characterized dermatologists’ views on patient across various practice settings.
A man in his early 50s presented to autoimmune dermatology clinic for 3 years of periarticular nodules on fingers that were painful with manipulation or minor trauma and symmetric polyarthralgia. What is your diagnosis?
We strive to educate medical providers of the possibility cellular transformation occurring as a parastomal complication and emphasize importance close monitoring, there is risk, although low, subsequent malignant transformation.