A5081280697- Microscopic Colitis
- Mycobacterium research and diagnosis
- Helicobacter pylori-related gastroenterology studies
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Treatments and Studies
- Esophageal and GI Pathology
- Cardiac Fibrosis and Remodeling
- Congenital heart defects research
- Abdominal vascular conditions and treatments
- Inflammatory Bowel Disease
- Cancer-related gene regulation
- Foreign Body Medical Cases
- Gastric Cancer Management and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Lung Cancer Treatments and Mutations
- Renal and Vascular Pathologies
- Gastrointestinal disorders and treatments
- Immunotherapy and Immune Responses
- Vascular anomalies and interventions
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Melanoma and MAPK Pathways
Peter MacCallum Cancer Centre
2018-2024
Eastern Health
2019-2023
The Royal Melbourne Hospital
2018-2021
The University of Melbourne
2019
UNSW Sydney
2014
Transcription factors play a crucial role in regulation of cardiac biology. FOG-2 is indispensable this setting, predominantly functioning through physical interaction with GATA-4. This study aimed to identify novel co-regulators further elaborate on its inhibitory activity The Art27 transcription factor was identified by yeast-2-hybrid library screen be protein partner. Characterisation revealed that co-expressed and GATA-4 throughout myocyte differentiation multiple structures the adult...
Marked elevations of alanine aminotransferase (ALT) are caused by a limited number underlying pathologies, including hepatic ischemia, drugs/toxins, viral hepatitis, and-rarely-autoimmune hepatitis. The aim this study was to determine the relative incidence pathologies resulting in ALT greater than 1000 IU/L and factors predicting clinical outcomes an Australian cohort.A retrospective cohort all adult patients with levels between January 2013 December 2015 conducted at large teaching...
Caustic ingestion is relatively common in developing countries and can result life-threatening sequelae. There limited understanding of the epidemiology incidence Australia.This statewide 10-year audit aims to document rate caustic injury a defined Australian pouplation.A retrospective review was conducted over 10 years (2007-2016), including all admissions hospitals Victoria. This includes population 5.9 million people 22 hospitals.Three hundred eighty-four cases were admitted hospital...
Introduction: Endoscopic scoring systems have not been established for immune-mediated colitis (IMC). Previous studies shown benefits from early endoscopic evaluation, but the value of endoscopy compared to clinical assessment remains uncertain. This study aims establish an system IMC and explore its utility in predicting need selective immunosuppressive therapy (SIT, infliximab or vedolizumab) symptoms severity. Methods: is a retrospective 14 centers worldwide including 674 patients with...