A5062646088- Neurotransmitter Receptor Influence on Behavior
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Child and Adolescent Psychosocial and Emotional Development
- Neuroscience and Neuropharmacology Research
- Schizophrenia research and treatment
- Child Abuse and Trauma
- Smoking Behavior and Cessation
- Neuroendocrine regulation and behavior
- Parkinson's Disease Mechanisms and Treatments
- Attention Deficit Hyperactivity Disorder
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Regulation of Appetite and Obesity
- Nicotinic Acetylcholine Receptors Study
- Pain Management and Treatment
- Prenatal Substance Exposure Effects
- Advanced Neuroimaging Techniques and Applications
- Computational Geometry and Mesh Generation
- Early Childhood Education and Development
- Psychosomatic Disorders and Their Treatments
- Mental Health Research Topics
- 3D Shape Modeling and Analysis
- Child and Animal Learning Development
- Ion channel regulation and function
Community College of Baltimore County
2024-2025
East Tennessee State University
2020-2021
University of California, Los Angeles
2011-2017
VA Greater Los Angeles Healthcare System
2013-2016
Neurobehavioral Systems
2015-2016
Los Angeles Medical Center
2016
University of California, Irvine
2013-2015
Institute of Molecular Medicine
2015
University of Toronto
2015
Centre for Addiction and Mental Health
2015
Impulsive behavior is thought to reflect a traitlike characteristic that can have broad consequences for an individual's success and well-being, but its neurobiological basis remains elusive. Although striatal dopamine D 2 -like receptors been linked with impulsive behavioral inhibition in rodents, role receptor function frontostriatal circuits mediating inhibitory control humans has not shown. We investigated this study of healthy research participants who underwent positron emission...
Motor response inhibition is mediated by neural circuits involving dopaminergic transmission; however, the relative contributions of signaling via D 1 - and 2 -type receptors are unclear. Although evidence supports dissociable to in rats associations humans, relationship between has not been evaluated humans. Here, we tested whether individual differences striatal related human subjects, possibly opposing ways. Thirty-one volunteers participated. Response was indexed stop-signal reaction...
In previous research, nicotine-dependent men exhibited lower putamen D2/D3 dopamine-receptor availability than non-smokers (Fehr et al.2008), but parallel assessments were not performed in women. Women and (19 light smokers, 18 non-smokers) tested for differences due to sex smoking striatal availability, using positron emission tomography with [18F]fallypride. Receptor was determined a reference region method, volumes whole-brain, voxel-wise analysis. Significant sex×smoking interactions...
https://youtu.be/RzKWRGm-J34 BACKGROUND The aim of this study was to determine if Adverse Childhood Experiences (ACE’s) are related physiological measures health. ACE’s associated with an increase in the inflammatory response. Chronic inflammation is linked diseases such as heart disease, lung and cancer well immunologic conditions. Lifestyle choices exercise dietary habits may potentially counteract those changes higher due anti-inflammatory properties choices. METHODS Participants visited...
Ranolazine [Ranexa; (+/-)-N-(2,6-dimethyl-phenyl)-(4[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazine] is novel anti-ischemic agent that has been shown to inhibit late I(Na) and I(Kr) have antiarrhythmic effects in various preclinical vitro models. This study was undertaken investigate the of ranolazine on drug-induced Torsade de Pointes (TdP) vivo. TdP induced by an blocker, clofilium, anesthetized, alpha(1)-agonist-sensitized rabbits. Clofilium prolonged QT interval corrected for heart...
Individuals with substance-use disorders exhibit emotional problems, including deficits in emotion recognition and processing, this class of also has been linked to dopaminergic markers the brain. Because associations between these phenomena have not explored, we compared a group recently abstinent methamphetamine-dependent individuals (n=23) healthy-control (n=17) on dopamine D2-type receptor availability, measured using positron emission tomography [18F]fallypride. The anterior cingulate...
We describe and analyze several ways to parallelize the rebuild of a grid acceleration structure used for interactive ray tracing dynamic scenes. While doing so, we also memory system performance on multi-core multi-processor system. In particular, present scalable sort-middle approach that uses minimum amount synchronization, scales many CPUs, becomes limited only by bandwidth. This algorithm is capable rebuilding grids within fraction second, enabling large multi-million triangle scenes
The development of high-affinity radiotracers for positron emission tomography (PET) has allowed quantification dopamine receptors in extrastriatal and striatal regions the brain. As these new have distinctly different kinetic properties than their predecessors, it is important to examine suitability models represent uptake, distribution, vivo washout. Using simplified reference tissue model, we investigated influence region choice on binding potential 18 F-fallypride, a D 2 /D 3 receptor...
Addiction is a growing problem in the United States. Rehabilitation facilities have exercise as component of their program, yet these are not always within reach every person with addictive tendencies. Understanding that addiction chronic disease treatable integrated treatment methods, it’s imperative to find root PURPOSE: Determine if there triangular relationship between addiction, physical activity, and adverse childhood experience (ACE) scores, looking specifically at psychological...