A5016608752- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Synthesis of heterocyclic compounds
- Synthesis and Biological Evaluation
- Quinazolinone synthesis and applications
- Phenothiazines and Benzothiazines Synthesis and Activities
- Crystallization and Solubility Studies
- Synthesis and Reactivity of Heterocycles
- Synthesis and Reactions of Organic Compounds
- X-ray Diffraction in Crystallography
- Synthesis and Reactivity of Sulfur-Containing Compounds
- 14-3-3 protein interactions
- Estrogen and related hormone effects
- Sulfur-Based Synthesis Techniques
- Synthesis of Organic Compounds
- Fluorine in Organic Chemistry
- Crystallography and molecular interactions
- HER2/EGFR in Cancer Research
- Click Chemistry and Applications
- Chemical synthesis and pharmacological studies
- Multicomponent Synthesis of Heterocycles
- Bioactive Compounds and Antitumor Agents
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Chemical Reaction Mechanisms
- Fullerene Chemistry and Applications
N.D. Zelinsky Institute of Organic Chemistry
2015-2024
Russian Academy of Sciences
1991-2015
Pyridin‐2‐yl‐ and 4,6‐dimethylpyrimidin‐2‐yl‐cyanamides entered into an alkylation reaction in the form of sodium salts. Pyridin‐2‐yl cyanamide 2 was alkylated at endo‐nitrogen atom pyridine ring, while 4,6‐dimethylpyrimidin‐2‐yl 1 effectively exo‐nitrogen amino group. The cyanamides with phenacylbromide gave corresponding acetophenone derivatives. As a result their intramolecular cyclization reactions 3‐(4,6‐dimethylpyrimidin‐2‐yl)‐5‐phenyloxazol‐2(3 H )‐imine case...
The article presents a method for the construction of new tricyclic system imidazo[1,2-b]pyrido[4,3-e][1,2,4]triazin-6(7Н)-ones based on subsequent reactions obtained 1,2-diamino-4-phenylimidazole ethyl ether 3-methyl-6-phenylimidazo[1,2-b][1,2,4]triazin-2-carboxylic acid with dimethylformamide dimethyl acetal and primary amines. structures compounds were confirmed using data from 1 Н 13 С NMR, HRMS, XRD analyses. We analyzed dependence absorption photoluminescence spectra structure quantum...
A preparation method for steroid‐based difluoroboron complexes has been developed using lumiestrone as a steroid example. Previously inaccessible lumiestrone‐based annulated at positions 16 and 17 of the D ring have prepared. Such may large synthetic potential heterofunctionalization steroids ring. An application borylation mixture Ac2O‐BF3•OEt2 significantly simplify "dimers" bearing two estrone moieties connected 2 2' via linker. Crystal structures key representatives determined by X‑ray...
The 3- R -thieno[3,2- d ]pyrimidine-2,4(1 H ,3 )-diones ( 5a- с ) and -2-thioxo-2,3-dihydrothieno[3,2- ]pyrimidin-4(1 )-ones 5d-g were synthesized using methyl 3-aminothiophene-2-carboxylate alkyl-, arylisocyanates isothiocyanates respectively, which in turn converted into its N- и S- alkyl derivates 8a-e, 9a-g ). 2-aminothieno[3,2- ]pyrimidin-4(3 )-one 14a-c , 16 received as a result the interaction with benzoyl- pyrimidin-2-yl cyanamides.