A5091375076- Enzyme function and inhibition
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Bone fractures and treatments
- Digestive system and related health
- Alkaline Phosphatase Research Studies
- Glycosylation and Glycoproteins Research
- Ion channel regulation and function
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Electrospun Nanofibers in Biomedical Applications
- Carbohydrate Chemistry and Synthesis
- Autoimmune and Inflammatory Disorders Research
- Proteoglycans and glycosaminoglycans research
- Diet, Metabolism, and Disease
- Protease and Inhibitor Mechanisms
- Amino Acid Enzymes and Metabolism
- Cholinesterase and Neurodegenerative Diseases
- Polyamine Metabolism and Applications
- Advanced Materials and Mechanics
- Pediatric health and respiratory diseases
- Bone Tissue Engineering Materials
- Rheumatoid Arthritis Research and Therapies
- Shoulder Injury and Treatment
- Infant Nutrition and Health
- Musculoskeletal synovial abnormalities and treatments
Oulu University Hospital
1981-2021
University of Oulu
1978-2020
Reumasäätiön sairaala
1981
University of Turku
1962-1971
Helsinki University Hospital
1968-1971
University of Helsinki
1968-1971
University of Sheffield
1969
The main isoenzyme of human prostatic acid phosphatases was purified by affinity chromatography on L(+)-tartrate linked to agarose and isoelectric focusing. enzyme a single protein when examined polyacrylamide gel electrophoreses, either as native or in the presence sodium dodecyl sulfate. analytical recovery activity 19%. specific 40 18 mumol/(min X mg) for hydrolysis 5.5 mmol/liter p-nitrophenyl phosphate at pH 4.8 37 degrees C. purification factor great 1900. molecular weight measured...
Abstract Background Hemolytic uremic syndrome (HUS) is a multisystemic disease. In nationwide study, we characterized the incidence, clinical course, and prognosis of HUS caused by Shiga toxin (Stx)–producing Escherichia coli (STEC) strains with emphasis on risk factors, disease severity, long-term outcome. Methods The data pediatric patients from 2000 to 2016 were collected medical records. STEC isolates fecal cultures non-HUS same time period whole genome sequencing analysis. Results...
The regional and cellular distribution of the high activity carbonic anhydrase isoenzyme (CA C or CA II) in mouse nervous system was investigated by an indirect immunoperoxidase (peroxidase-antiperoxidase) method using cross-reactive antibodies prepared against human C. In mature brain overall strong specific reactivity revealed heavily myelinated nerve tracts, main immunostaining originating from small, intensively reacting cells interpreted as oligodendrocytes myelin sheaths. An obvious...
The specificities of carbonic anhydrase isoenzyme C (CA C) and glial fibrillary acidic (GFA) protein as immunocytochemical markers for different cell populations in human brain retina were studied using indirect immunofluorescence peroxidase-antiperoxidase complex methods. With antibodies against CA C, only those cerebral cells that morphologically oligodendrocytes Müller the showed positive immunostaining reaction, whereas GFA selectively labeled astrocytes a part fibers inner layers...
Proximal humerus fractures comprise approximately 2% of all pediatric fractures. In general, upper extremity have increased in children. However, recent trends proximal are not analyzed yet. The aim was to study the incidence and treatment children.All 300 children, aged < 16 years, who suffered from a fracture catchment area Oulu University Hospital, Finland, between 2005 2015, were included. Radiographs reviewed, patients, injuries, treatments, outcomes comprehensively studied. Annual...
Abstract Sulphoglycoprotein antigens of the foetal alimentary canal have been studied by immunofluorescence technique, and presence sulphomucins demonstrated histochemically from adjacent sections. The material consisted 39 foetuses between 6 16 weeks gestation. A supplementary autopsy series newborns was same techniques. three sulphoglycoprotein found earlier in normal pathological adult gastric mucosa appeared 7 8 gestation all were present epithelium. typical location these showed...
The elbow is the joint that most usually dislocates in children. In contrast to widely known recent increase incidence of upper-extremity fractures and their operative treatment children, potential trends dislocation are not clear. this study we aimed clarify epidemiology childhood dislocation, particular change treatment. A population-based was performed evaluate annual characteristics injury, patients All children < 16 years age with an 1996–2014 Oulu University Hospital District, Finland,...
OIKARINEN, JORMA M.D.; KORHONEN, L. KALEVI M.D., PH.D.Editor(s): URIST, MARSHALL R. M.D. Author Information
The carbohydrate-rich compounds in the epithelial cells of colonic mucosa man are characterized by periodate-reactivity and presence both acid acetyl radicals. These radicals partially prevent periodate oxidation, but on removal sulfate or groups intensity PAS-reaction is greatly increased. with labile to a mild hydrolysis after deacetylation, also sialidase digestion, which suggests an N-acetyl-O-diacetyl-like form sialic mucosubstances. benign neoplasms (adenomatous polyps villous...
The localization of carbonic anhydrase (CA) was studied in rat skeletal muscles with the use immunohistochemical (peroxidase-antiperoxidase) method. CA observed all those fibers that also showed pH 4.3 stable actomyosin adenosine triphosphatase activity (type I fibers), but reverse did not necessarily hold. More specifically, apparently localized I-bands, and a weak reaction sarcolemma. function muscle is possibly connected greater demands on CO2 transport buffer system adapted to...
Severe trampoline injuries in children and adolescents are rare; however, minor common their incidence is increasing. most commonly head neck injuries. They may result long-term morbidity. This study aimed to illustrate these severe find out risk factors. a population-based, prospective the Oulu region of Finland completed over 2 years (May 1, 2015 April 31, 2017). All (<16 age) with were included. Cervical spine fractures, chest wall skull lesions internal organs, hip knee dislocations,...
Experimental fibular defects in 16 rats were filled with an acid decalcified homogenous bone matrix (bone inductive material). Autogenous grafts corresponding the other legs of same served as controls. After 3 months, 11 material healed bony union, but only 4 treated autogenous had healed. The results suggest that can repair are too large to be by grafts.
The preferred surgical fixation of forearm shaft fractures in children is Elastic Stable Intramedullary Nailing (ESIN). Due to known disadvantageous effects metal implants, a new method using biodegradable polylactide-co-glycolide (PLGA) intramedullary nails has been developed but its long-term outcomes are unclear. aim this study was compare the Biodegradable (BIN) ESIN and assess biodegradation implants via magnetic resonance imaging (MRI). population prospective, randomized trial...