A5013854077- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Birth, Development, and Health
- Genomics, phytochemicals, and oxidative stress
- Cerebrovascular and genetic disorders
- Neonatal Respiratory Health Research
- Fibroblast Growth Factor Research
- Proteoglycans and glycosaminoglycans research
- Glutathione Transferases and Polymorphisms
- Connective tissue disorders research
- Preterm Birth and Chorioamnionitis
- Prenatal Screening and Diagnostics
- Complement system in diseases
- Estrogen and related hormone effects
- Gestational Diabetes Research and Management
- Bladder and Urothelial Cancer Treatments
- Connective Tissue Growth Factor Research
- Virus-based gene therapy research
- Epigenetics and DNA Methylation
- Axon Guidance and Neuronal Signaling
- Occupational and environmental lung diseases
- Moyamoya disease diagnosis and treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Adipokines, Inflammation, and Metabolic Diseases
- Hemoglobinopathies and Related Disorders
Marche Polytechnic University
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2024-2025
Istituto Nazionale di Riposo e Cura per Anziani
2024-2025
Polytechnic University of Puerto Rico
2016
Ospedali Riuniti di Ancona
1996-2015
University of Turin
2004-2005
Ovarian cancer is one of the most dangerous gynecologic cancers worldwide and has a high fatality rate due to diagnosis at an advanced stage disease as well recurrence occurrence chemotherapy resistance. In fact, chemoresistance weakens therapeutic effects, worsening outcome this pathology. Solute Carrier Family 7 Member 11 (SLC7A11, also known xCT) functional subunit Xc− system, anionic L-cystine/L-glutamate antiporter expressed on cell surface. SLC7A11 expression significantly upregulated...
Leptin is a circulating hormone which plays an important role in the regulation of energy balance, haemopoiesis and reproduction. its receptor (leptin-R) are localized human placental tissue but their function not known. In this study we have investigated expression leptin leptin-R placenta with particular attention to extravillous cytotrophoblastic cell islands columns play pivotal trophoblast invasion growth. We demonstrate that immunoreactivity shows strong distal cells invading basal...
Pregnancy is generally studied as a biological interaction between mother and fetus; however, the father, with his characteristics, lifestyle, genetics, living environment, by no means unrelated to outcome of pregnancy. The half fetal genetic heritage paternal derivation can be decisive in cases inherited chromosomal disorders, result de novo alterations. In addition strictly pathological aspects, genetics may transmit thrombophilic traits that affect implantation vascular construction...
Human trophoblast cell surface antigen 2 (Trop-2) is a 40-kDa transmembrane glycoprotein that was first identified as marker of human cells. Trop-2 acts on proliferation, adhesion, and migration by activating number intracellular signalling pathways. Elevated expression has been demonstrated in several types cancer correlated with aggressiveness poor prognosis. Since no data are available bladder (BC), the purpose study to determine its levels tissue specimens from normal individuals...
In this review, we comprehensively present the literature on circulating microRNAs (miRNAs) associated with preeclampsia, a pregnancy-specific disease considered primary reason for maternal and fetal mortality morbidity. miRNAs are single-stranded non-coding RNAs, 20–24 nt long, which control mRNA expression. Changes in miRNA expression can induce variation relative level influence cellular homeostasis, strong presence of all body fluids has made them useful biomarkers several diseases....
The placenta plays a key role in several adverse obstetrical outcomes, such as preeclampsia, intrauterine growth restriction and gestational diabetes mellitus. early identification of at-risk pregnancies could significantly improve the management, therapy prognosis these pregnancies, especially if are identified first trimester. aim this review was to summarize possible biomarkers that can be used diagnose placental dysfunction and, consequently, pregnancies. We divided into proteins...