A5057137048- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- Prostate Cancer Treatment and Research
- Concrete and Cement Materials Research
- Advanced Fiber Optic Sensors
- Advanced machining processes and optimization
- Cancer, Lipids, and Metabolism
- Advanced Surface Polishing Techniques
- Advanced Combustion Engine Technologies
- Innovative concrete reinforcement materials
- Fire effects on concrete materials
- Hippo pathway signaling and YAP/TAZ
- Thermal Analysis in Power Transmission
- Vehicle emissions and performance
- Air Quality and Health Impacts
- Carbon and Quantum Dots Applications
- Building Energy and Comfort Optimization
- Landslides and related hazards
- Refrigeration and Air Conditioning Technologies
- PI3K/AKT/mTOR signaling in cancer
- Synthesis and Properties of Aromatic Compounds
- Cancer-related molecular mechanisms research
- Leaf Properties and Growth Measurement
- Simulation and Modeling Applications
- Kruppel-like factors research
North China University of Water Resources and Electric Power
2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2018-2024
Wenzhou Medical University
2018-2024
Huazhong University of Science and Technology
2024
Shaanxi Normal University
2021-2024
Zhengzhou University
2021-2023
Chongqing Jiaotong University
2020-2022
University of Alabama at Birmingham
2021-2022
BioMimetic Systems (United States)
2022
Biosensores (Spain)
2022
This paper presents results from experimental work on mechanical properties of geopolymer concrete, mortar and paste prepared using fly ash blended slag. Compressive strength, splitting tensile strength flexural tests were conducted large sets ordinary after exposure to elevated temperatures. From Thermogravimetric analyzer (TGA), X-ray diffraction (XRD), Scanning electron microscope (SEM) test results, the exhibits excellent resistance temperature. strengths C30, C40 C50 show incremental...
Abstract Human tubulin beta class IVa (TUBB4A) is a member of the β-tubulin family. In most normal tissues, expression TUBB4A little to none, but it highly expressed in human prostate cancer. Here we show that high levels are associated with aggressive cancers and poor patient survival, especially for African-American men. Additionally, cancer cells, knockout (KO) reduces cell growth migration induces DNA damage through increased γH2AX 53BP1. Furthermore, during constricted migration,...
Water resource health is one of the necessary conditions for society to achieve sustainable development. Due predominant focus most studies on relatively short time spans, with limited attention long series and spatial trends, this study, using various regions Henan Province as a case constructs water security assessment framework based DPSIR model encompassing Drivers (D), Pressures (P), State (S), Impact (I), Response (R) dimensions, selection 19 evaluation indicators. Based index system,...
Chiral carbon dots are prepared by a simple and one-step hydrothermal reaction at 180 °C for 2 h using citric acid <sc>d</sc>-proline as precursors, which show high asymmetric catalytic activity enantioselective direct aldol condensation.
Abstract Deregulation of microRNAs contributes to the abnormal cell growth which is frequently observed in cancer. In current study, we detected expression and regulatory relationship between miR‐10a Lysine‐specific demethylase 4A (KDM4A) reveal their function prostate cancer (PCa) progression. We found that levels were significantly decreased PCa lines comparison with normal epithelial line RWPE‐1. Downregulation was also tumor tissues from patients compared adjacent tissues. Enhanced...
The molecular complexity of colorectal cancer poses a significant challenge to the clinical implementation accurate risk stratification. There is still an urgent need find better biomarkers enhance established stratification and guide risk-adapted treatment decisions.
Prostate cancer (PCa) is the most frequently diagnosed among men. However, major modifiable risk factors for PCa are poorly known and its specific mechanism of progression remains unclear. Here we reported that, in prostate cells, autophagy level was elevated under hypoxic condition, as well mRNA protein ATG5, which an important gene related to autophagy. Furthermore, found HIF1α could directly bind promoter ATG5 promote expression on transcriptional by luciferase assay ChIP assay....
A micro-reciprocating piston internal combustion engine with liquid hydrocarbon fuel has the potential to supply ultrahigh density energy micro electro mechanical system because of its high-density energy, simple structure, and mature conversion principle. However, diagnostic test characteristics reciprocating shows that are poor, rate was lower duration more than 50 °CA. The mean indicated pressure (Pmi) value only 0.137 MPa, stability very cycle variation Pmi up 60%. To improve...
To address the challenges of performing in-situ tests on riverbed overburden gravel, this study employs three scaling methods—equal mass substitution, similar gradation, and mixed method—to investigate original gradation gravel. Large-scale triaxial consolidated drained shear were conducted to evaluate effects maximum particle size reduction ratio (M) confining pressure stress–strain behavior, fractal dimension, breakage, parameters Duncan-Chang model (an elastic describing nonlinear...
BACKGROUND:Prostate cancer is a common type of malignant tumor invading the male reproductive-urinary system, which has increasing incidence worldwide. Androgen receptor variant 7 (AR-V7) participates in regulating prostate cell proliferation and gene expression. This study aimed to investigate expression AR-V7 circulated cells (CTCs) patients with assess its correlation drug sensitivity against enzalutamide or abiraterone. MATERIAL AND METHODS:Blood samples were collected for separating...
The spatio-temporal evolution of the temperature induced over carbon fiber reinforced polymer (CFRP) laminates during drilling is monitored in real-time using a distributed optical sensor based on frequency-domain reflectometry (OFDR). proposed measurement technique enables simultaneous monitoring thousands independent points CFRP plate machining, being special interest to measure internal workpiece. Experimental results validate use OFDR-based sensing for this novel application,...
Abstract Background The PI3K/AKT/mTOR signaling pathway is essential for initiation and progression of prostate cancer. However, there has been no a comprehensive comparison the role these nodes in tumor progression. Methods With genetically engineered animal models, we compared impact prostate‐specific deletions Pten , Tsc1 Tsc2 activation Akt1 on Also, assessed expression genetic alterations PTEN AKT1 TSC1 TSC2 human primary cancers. Results For mice, conditional knockout (cKO) led to...
<title>Abstract</title> In response to the difficulty of conducting in-situ tests on gravel materials riverbed cover layers, this study investigates their mechanical properties using a scaled-down grading method. Three methods, namely equivalent substitution method, similar and hybrid are employed based original from layers. Through large-scale triaxial consolidation drainage shear tests, effects reduction factor 𝑀 maximum particle size confining pressure stress-strain relationship, fractal...
More and more office buildings are built consequently, the building energy-consumption increases especially air conditioning energy consumption. The consumption of is monitored in an Qingdao, test results show that refrigerator installed capacity too large COP low, cooling circle pumps chilled water oversize transport factor lower than standard value, efficiency tower also very low. Based on experimental result, corresponding saving measures proposed.
This article has been retracted by the publisher.
Distributed fiber sensing based on optical frequency-domain reflectometry is proposed for monitoring the two-dimensional temperature profile resulting during drilling carbon reinforced polymers. Experimental results demonstrate unique features and advantages provided by this technology.