Cemal Akay

ORCID: 0000-0002-2306-5451
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About
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Research Areas
  • Pancreatitis Pathology and Treatment
  • Analytical Methods in Pharmaceuticals
  • Trace Elements in Health
  • Heavy Metal Exposure and Toxicity
  • Analytical Chemistry and Chromatography
  • Liver Disease Diagnosis and Treatment
  • Antibiotics Pharmacokinetics and Efficacy
  • Neonatal Health and Biochemistry
  • Carcinogens and Genotoxicity Assessment
  • Drug-Induced Hepatotoxicity and Protection
  • Aldose Reductase and Taurine
  • Essential Oils and Antimicrobial Activity
  • Air Quality and Health Impacts
  • Iron Metabolism and Disorders
  • Aluminum toxicity and tolerance in plants and animals
  • Effects of Radiation Exposure
  • Selenium in Biological Systems
  • Advancements in Transdermal Drug Delivery
  • Apelin-related biomedical research
  • Bone health and osteoporosis research
  • Radiation Dose and Imaging
  • Electromagnetic Fields and Biological Effects
  • Pharmacological Effects and Assays
  • Glutathione Transferases and Polymorphisms
  • Autism Spectrum Disorder Research

Turkish Armed Forces
2008-2020

Erciyes University
2016

Gülhane Askerî Tıp Akademisi
2002-2015

Military Medical Academy
2004-2013

New York Academy of Medicine
2013

Süleyman Demirel University
2006

Gazi University
1999-2006

Hacettepe University
2003

There has been a resurgence of interest in studies concerning the role elements development and maintenance skeleton. The aim study was to assess plasma red blood concentrations some postmenopausal women with osteoporosis.Seventy-seven osteoporosis aged 61 years (median interquartile range, 7.5; 46 74) age- BMI-matched healthy 60 8.0; 44 76) were included study. Element cells including magnesium (Mg), zinc, copper, manganese, selenium measured by atomic absorption spectrophotometry both...

10.47102/annals-acadmedsg.v37n7p564 article EN Annals of the Academy of Medicine Singapore 2008-07-15

Our aim was to test whether the presence of three hydraulic calcium silicate dental cements – MTA Angelus, Fillapex, and Theracal LC in extraction socket an vivo model, would affect levels aluminium (Al) plasma liver. Following anesthesia, right upper incisor each male Wistar albino rat extracted polyethylene tubes filled with or were inserted into depth gingival tissue sutured. The rats killed 7, 30, 60 d after operation. Blood liver samples obtained from before they killed, Al measured by...

10.1111/eos.12238 article EN European Journal Of Oral Sciences 2015-12-26

Various protocols may be used for acute pancreatitis treatment. Recently, the benefit of hyperbaric oxygen (HBO) has been demonstrated. To clarify mechanism HBO on process pancreatitis, we determined levels antioxidant enzymes in an model. Forty-five Sprague-Dawley rats were randomly divided into three groups: Group I: sham group (n=15), II: III: undergoing therapy (n=15). was applied postoperatively 5 days, two sessions per day at 2.5 fold absolute atmospheric pressure (ATA) 90 min....

10.33549/physiolres.930284 article EN cc-by-nc Physiological Research 2003-01-01

Occupational exposure to low levels of ionizing radiation (IR) in radiology department staff may affect their antioxidant status. The aim this study was evaluate the oxidative stress parameters that are occupationally exposed IR a hospital setting.The population included 40 and 30 control subjects. doses ranged between 0.10 3.8 milligray (mGy) per month. subjects' status determined by measuring activities copper zinc-superoxide dismutase (CuZn-SOD), selenium dependent glutathione peroxidase...

10.3109/09553002.2012.702295 article EN International Journal of Radiation Biology 2012-06-14

Free oxygen radicals and insufficiency of antioxidant enzymes have been implicated in the pathogenesis hypertension disease (HD). Trace elements function as a co-factor enzymes. The system trace investigated many different studies including HD, but these subjects not whole patients.The aim present study was to investigate antioxidative hypertensive patients given antihypertensive therapy.We examined malondialdehyde superoxide dismutase activities together with copper zinc levels plasma 102...

10.1097/00004872-200306000-00022 article EN Journal of Hypertension 2003-05-24

Ionizing radiation is known to induce mutations and cell transformations, predominantly by causing single-strand double-strand DNA breakage, thereby leading chromosome instability carcinogenesis. The aim of this study was evaluate genotoxic effects in hospital staff exposed low-dose ionizing comparison with a selected control group, using the cytokinesis-blocked micronucleus (CBMN) sister chromatid exchange (SCE) tests peripheral blood lymphocytes. included 40 radiology 30 subjects....

10.1177/0748233710365693 article EN Toxicology and Industrial Health 2010-04-06

Background: In obese populations, oxidative stress plays a major role in the pathogenesis of serious diseases such as diabetes, coronary heart disease, and atherosclerosis. this study, we investigated status children to nitrite/nitrate glutathione peroxidase levels, their relation with insulin resistance (IR).

10.1515/jpem-2011-0397 article EN Journal of Pediatric Endocrinology and Metabolism 2012-01-01

Introduction Ciprofloxacin and meropenem have effects on intestinal bacteria that are responsible for pancreatic infection, the basis of recent data it has been argued probiotics, especially those used in food industry, could improve efforts to prevent treat secondary infections by inhibiting bacterial translocation. Aims To evaluate probiotic treatment alone or combination with early administration two different antibiotics serum amylase, histopathology, translocation, oxidative markers....

10.1097/00006676-200305000-00009 article EN Pancreas 2003-05-01

It has been demonstrated that hyperbaric oxygen (HBO) is useful as an adjunctive therapy for Crohn's disease. However, its effects on ulcerative colitis have not investigated. In the present study, HBO was tested acetic acid-induced colitis, and antioxidant systems were evaluated to clarify possible mode of action. Thirty-six Sprague-Dawley rats randomly divided into three groups: sham control (Group I), induced by acid without any II), treated with III). given 5 days, 2 sessions per day at...

10.33549/physiolres.930416 article EN cc-by-nc Physiological Research 2004-01-01

Abstract The transition metal zinc is an essential element for normal development and function of biological systems including the central nervous system (CNS). Zinc may be important trace etiology symptoms subgroups autistic children because it catalytic or structural many proteins neural activity control neuronal death. aim this study was to evaluate status in with disorder. Plasma, erythrocyte, hair levels were measured by atomic absorption spectrophotometry 45 39 children, respectively....

10.1002/jtra.20002 article EN The Journal of Trace Elements in Experimental Medicine 2004-01-01

Objective: Infection is a major complication and risk factor of cerebrospinal fluid (CSF) shunting procedures. Recently, antibiotic-impregnated shunt systems have been developed in an attempt to prevent or reduce the CSF infection. The aim this study was determine efficacy silver-impregnated polyurethane ventricular catheter for patients with infected hydrocephalus. Methods: Seven who had hydrocephalus high protein level positive culture underwent implantation ventriculoperitoneal catheter....

10.1179/174313209x380973 article EN Neurological Research 2008-11-27

Prostate cancer is the second most common in men worldwide. Although aetiology of this disease remains largely unclear, several lines evidence suggest that oxidative stress plays a role prostate carcinogenesis. The antioxidant enzyme glutathione peroxidase 1 (GPX1) part enzymatic defence, preventing damage to DNA, proteins and lipids by detoxifying hydrogen lipid peroxides may contribute development. Some studies indicate an association between GPX1 Pro198Leu polymorphism increased risk...

10.1177/0960327111411499 article EN Human & Experimental Toxicology 2011-06-02

10.1016/s0731-7085(02)00460-0 article EN Journal of Pharmaceutical and Biomedical Analysis 2002-10-28

Activation of pancreatic stellate cells (PSCs) is a key event in fibrosis. Xanthine oxidase-derived free radicals are involved the mechanism chronic pancreatitis (CP). We here searched vivo effects allopurinol on PSC activation and its relation to tissue oxidative stress histological findings rat CP.Rat CP was induced with intraductal trinitrobenzene sulfonic acid groups 1 (n = 16) 2 10). Group 3 10) received saline. Four weeks after induction, group (200 mg/kg, s.c.), After 4 weeks,...

10.1097/mpa.0b013e31806dbaaa article EN Pancreas 2007-11-01

General anaesthetics are often used in patients who under oxidative stress due to a critical illness or surgical trauma. Some may worsen and some act as antioxidants. The aim of this study was evaluate liver, brain, kidney, lung tissue rats exposed desflurane sevoflurane unexposed rats. animals were divided three groups: control (received only air); (8 %), (4 %). After four hours exposure, we evaluated the levels malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase...

10.2478/10004-1254-62-2011-2096 article EN Archives of Industrial Hygiene and Toxicology 2011-06-01
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