A5011868936- melanin and skin pigmentation
- Cutaneous Melanoma Detection and Management
- Nail Diseases and Treatments
- Hair Growth and Disorders
- Nonmelanoma Skin Cancer Studies
- Autoimmune Bullous Skin Diseases
- Dermatology and Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Dermatologic Treatments and Research
- Cancer and Skin Lesions
- Genetic and rare skin diseases.
- Urticaria and Related Conditions
- Psoriasis: Treatment and Pathogenesis
- Acne and Rosacea Treatments and Effects
- Skin Protection and Aging
- Skin and Cellular Biology Research
- Mast cells and histamine
- Skin Diseases and Diabetes
- Allergic Rhinitis and Sensitization
- Genital Health and Disease
- Ocular Diseases and Behçet’s Syndrome
- Plant Pathogens and Fungal Diseases
- Dermatological and Skeletal Disorders
- Oral Health Pathology and Treatment
- Facial Rejuvenation and Surgery Techniques
Güven Hospital
2020-2022
Izmir Tepecik Eğitim ve Araştırma Hastanesi
2021
Gülhane Askerî Tıp Akademisi
2002-2017
Military Medical Academy
2006-2016
New York Academy of Medicine
2013
Ege University
2013
Denizli Devlet Hastanesi
2013
Muğla University
2013
Ankara Mevki Asker Hastanesi
2013
Turkish Armed Forces
2002-2008
Abstract Internalized stigma is the adoption of negative attitudes and stereotypes society regarding a person's illness. It causes decreased self‐esteem life‐satisfaction, increased depression suicidality, difficulty in coping with The primary aim this study was to investigate internalized state psoriatic patients identify factors influencing stigma. secondary correlation quality life perceived health status. This multicentre, cross‐sectional comprised 1485 patients. There significant...
Androgenetic alopecia (AGA) is undoubtedly the most common form of hair loss in males. It a condition which may cause cosmetic and psychosocial problems androgen-dependent cases. In this open, randomized comparative study we evaluated efficacy oral finasteride 5% topical minoxidil treatment for 12 months 65 male patients with mild to severe AGA.We randomly assigned 40 (61.53%) receive 1 mg/day months, 25 (38.47%) applied solution twice daily months.There were no significant differences...
ABSTRACT Vitiligo is a common, idiopathic, acquired, depigmenting disease characterized by loss of normal melanin pigments in the skin. The most interesting treatment methods for extensive vitiligo involve psoralen plus ultraviolet A (PUVA) therapy and (UV)‐B phototherapy, particularly narrow‐band UV‐B. In this randomized comparative study, we investigated safety efficacy narrow band B as monotherapy combination with topical calcipotriol generalized vitiligo. Of 40 patients enrolled 15 were...
ABSTRACT Melasma is a common acquired disorder of facial hyperpigmentation. In this study we investigated the efficacy and safety combined treatment regimen including serial glycolic acid peels, topical azelaic cream adapalene gel in recalcitrant melasma. Twenty‐eight patients with melasma were enrolled prospective, randomized, controlled trial lasting 20 weeks. The group receiving chemical peels underwent combination 20% (b.i.d.) 0.1% (q.i.d., applied at night). control received only...
BACKGROUND Various treatment regimens have been used in scars. The literature offers little consensus about appropriate therapy. OBJECTIVE To compare intralesional triamcinolone acetonide (TAC) alone or combined with onion extract keloidal and hypertrophic MATERIALS AND METHODS Fourteen patients were treated TAC gel, 13 alone. Findings recorded graded at each visit (weeks 0, 4, 12, 20). scores before week 20 compared. RESULTS Twenty-seven [17 men (63%) 10 women (37%) aged 15 to 73 (average...
Skin problems are common in amputee patients. These may restrict the normal use of a prosthetic limb. We aimed to determine range, incidence, causes and patterns dermatological seen population amputees.One hundred forty two amputees, were enrolled study. Age, sex, age at time amputation, level reason for types prosthesis noted. Dermatological recorded. Stumps swabbed bacteriological mycological examination, patch tests performed suspected patients.Of these 142 patients, 139 (97.9%) males 3...
Seborrheic dermatitis (SD) is a chronic inflammatory disorder that mainly affects the seborrheic region. While ketoconazole often used, pimecrolimus has been used successfully in SD.To compare efficacy and tolerability of comparison with treatment SD.A total 48 patients SD were included study. Patients randomized into two groups: 23 25 groups, respectively. Clinical measures assessed by erythema, scaling infiltration, which evaluated using four-point scale (0 to 3) at 2, 6, 12 weeks.Of these...
Background: With regard to the lack of effective treatment modalities for childhood localized vitiligo, search newer therapeutic agents continues.Objective: To conduct an open, comparative trial evaluate clinical efficacy and safety topical mometasone cream pimecrolimus in vitiligo.Methods: Fifty patients with vitiligo were included study. Patients treated 3 months either (0.1%) once daily or (1%) twice daily.Results: Forty patients, 20 from each group, completed The two drugs found be...
As is the case with many other autoimmune diseases, there an association between vitiligo and HLA complex. subtypes vary racial/ethnic background. The purpose of this study was to determine which class I antigens II alleles are associated Turkish patients. Forty‐one patients 61 healthy control subjects were typed for alleles. Thirty‐three out 41 100 transplant donors antigens. DNA typing performed by polymerase chain reaction/sequence specific primer method II. serological method. frequency...
To evaluate and compare the safety efficacy of 10% potassium hydroxide (KOH) solution salicylic lactic acid (SAL + LAC) combination in treatment molluscum contagiosum (MC).26 patients with MC randomized into two groups. 12 treated KOH 14 SAL LAC for 6 weeks. Parents were instructed to apply medication once daily only lesions at study onset. Assessment response side effects was performed 2, 4 weeks treatment. Newly acquired not included study.At end therapy, 83.3% (n = 10) group demonstrated...
BACKGROUND Various treatment regimens have been used in scars. The literature offers little consensus about appropriate therapy. OBJECTIVE To compare intralesional triamcinolone acetonide (TAC) alone or combined with onion extract keloidal and hypertrophic MATERIALS AND METHODS Fourteen patients were treated TAC gel, 13 alone. Findings recorded graded at each visit (weeks 0, 4, 12, 20). scores before week 20 compared. RESULTS Twenty-seven [17 men (63%) 10 women (37%) aged 15 to 73 (average...
OBJECTIVE: In this open, randomized and comparative study, the safety efficacy of systemic fluconazole, itraconazole terbinafine was investigated in 50 patients with distal subungual toenail onychomycosis diagnosed clinically mycologically. The positive mycology also microscopy negative culture were investigated. METHODS: treatment duration 3 months, follow-up period 6 months. Patients randomly assigned: 16 received 150 mg fluconazole once weekly, 18 200 twice daily meals during first week...
BACKGROUND: Topical colchicine has been reported to be an effective treatment for actinic keratoses, but the optimal concentration not fully defined. OBJECTIVE: The aim of this study was further support beneficial effect topical therapy and compare efficacy safety two different concentrations cream, 0.5% 1%. METHODS: Sixteen patients with keratoses were enrolled in comparative randomized study. Eight applied 1% twice daily on their lesions while other eight treated a cream 10 days. Some...
Abstract: Toxic epidermal necrolysis and Stevens–Johnson syndrome are severe skin reactions, usually to drugs, associated with a widespread destruction of the epidermis. Widespread purpuric macules detachment less than 10% body surface is indicative syndrome, whereas between 30% called Stevens–Johnson‐toxic overlap. Epidermal involving more total designated as toxic necrolysis. These generalized reactions known occur in association various drugs. Treatment primarily supportive care, there no...
Abstract Background Topical drugs enhance the therapeutic effects of ultraviolet (UV)‐based therapy for psoriasis. However, their efficacy has yet to be established in a clinical trial. Objectives This study aimed compare targeted microphototherapy alone and combination with psoralen or calcipotriol treatment plaque‐type Methods Thirty individuals, affected by psoriasis, were treated narrowband UVB phototherapy (Group 1), gel 2), ointment 3) three times per week based on predetermined...
AbstractFollicular mucinosis is a rare disorder of unknown etiology characterized by accumulation mucin in the sebaceous glands and outer root sheaths hair follicles. It divided into primary benign type secondary mostly associated with lymphomas. No effective standard therapy for follicular available. We describe case 21-year-old Caucasian male who had papules, nodules, erythematous plaques on his left shoulder, arm, right scapular region. He was diagnosed as generalized mucinosis, treated...
Infantile acne is an uncommon condition in pediatric age. We determined the efficacy and safety of adapalene gel 0.1% treatment infantile acne. Twelve patients were enrolled for application once daily over a 16-week period. Efficacy evaluation included counting inflammatory noninflammatory lesions by physician global improvement. After 16 weeks all followed up 1-year The time clearance was 3 months four (33%) 4 eight (67%) (median 3.4 months). Adapalene produced reductions counts. Limited...
Lipoid proteinosis (LP) is a rare autosomal recessive genodermatosis characterized by deposition of amorphous hyaline material in different parts the body, especially skin and mucous membranes. Disfiguring lesions predominantly affect facial appearance. There no curative therapy treatment options are limited to symptomatic approaches. Facial disfigurement this disease may have an huge negative effect on patients' psychology quality life. With regard, patients benefit very much from...
Internalized stigma, adoption of negative attitudes and stereotypes the society regarding persons' illness, has not been studied previously in pediatric psoriasis patients.We aimed to investigate internalized stigma patients determine differences according factors affecting compared adult patients.This multicenter, cross-sectional, comparative study included 125 (55 female, 70 male; mean age±standard deviation [SD], 14.59±2.87 years) 1,235 (577 658 age±SD, 43.3±13.7 years). Psoriasis Stigma...
A 20‐year‐old man presented with skin lesions on his forearms and legs that had started to appear at 3 years of age. On exposure the sun, became red. He suffered from dysphagia dysdefecation. His parents’ marriage was not consanguineous, they were well. five brothers sister also stated one aunt's sons uncle's son same lesions, but we unable examine them. Physical examination revealed a reticulated pattern atrophy, pigmentation, erythema, telangiectasia neck ( Fig. 1 ), shoulders, popliteal...