A5049883733- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Inflammatory mediators and NSAID effects
- Helicobacter pylori-related gastroenterology studies
- Esophageal and GI Pathology
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Treatments and Studies
- Drug-Induced Adverse Reactions
- Metastasis and carcinoma case studies
- HER2/EGFR in Cancer Research
- Pancreatic and Hepatic Oncology Research
- Biliary and Gastrointestinal Fistulas
- Cancer, Lipids, and Metabolism
- Potassium and Related Disorders
- Liver Disease and Transplantation
- Pancreatitis Pathology and Treatment
- Probiotics and Fermented Foods
- Genetic factors in colorectal cancer
- Abdominal vascular conditions and treatments
- Platelet Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Cardiac Arrhythmias and Treatments
Nippon Medical School
2008-2024
Okayama University Hospital
2024
Kurashiki Medical Center
2024
Kurashiki Central Hospital
2024
University Gastroenterology
2023
The Japanese Society of Gastroenterological Surgery
2022
Kindai University
2019
Nippon Medical School Hospital
2005-2016
Hy-Line (United States)
2009
Natural (Czechia)
2006
Clinical trials of probiotic treatment for Crohn's disease (CD) have yielded conflicting results. This study assessed the clinical usefulness combined and prebiotic therapy in active CD.Ten CD outpatients without history operation were enrolled. Their mean (+/-SD) age was 27 +/- 7 years main symptoms presented diarrhea abdominal pain. Patients' initial therapeutic regimen aminosalicylates prednisolone failed to achieve remission. Patients thus initiated on a synbiotic therapy, consisting...
Nonsteroidal anti-inflammatory drugs (NSAIDs) induce small intestinal mucosal injuries. The concentrations of NSAIDs, bile acids and flora may differ in the proximal distal parts intestine. This study aimed to analyse types distributions NSAID-induced injuries.In total 55 healthy male volunteers were examined using baseline capsule endoscopy (CE). Subjects then undertook a 14-day regimen NSAID medication (diclofenac sodium, 75 mg day(-1)) with proton-pump inhibitors (omeprazole 20 as...
Several studies have shown the value of capsule endoscopy and double balloon (DBE) in small-intestinal bleeding. The purpose this study was to evaluate impact results on subsequent DBE examination, 1-year clinical outcome combined approach patients with obscure gastrointestinal bleeding (OGIB).A total 45 consecutive OGIB underwent endoscopy. Patients positive for biopsy or therapy, those negative further assessment possible diagnostic misses Tumors, ulcerations, vascular lesions were...
Goals: The aim is to elucidate the efficacy and safety of double-balloon endoscopy (DBE) for small bowel capsule (SBCE) retrieval from stricture follow outcome where SBCE was entrapped. Background: retention a serious adverse event most retained capsules are retrieved by surgery. There still no report analyzing follow-up patients with after entrapped SBCEs DBE. Methods: This study designed retrospective cohort study. Subjects were 12 consecutive attempted using Success rate DBE, surgical...
Heregulin (HRG/NRG) ligation to erbB3/4 promotes their respective heterodimerization with erbB2, and consequent erbB2 tyrosine phosphorylation. Although HRG has been shown be expressed in a variety of cancer tissues, its expression role colon have yet clarified. We therefore examined the link between these erbB receptors, relationship vascular endothelial growth factor (VEGF) cancer.We analyzed effects on VEGF secretion 6 colorectal cell lines by enzyme-linked immunosorbent assay,...
The ErbB family consists of four proteins including (EGFR)/ErbB1, ErbB2, ErbB3, and ErbB4, plays a crucial role in the promotion multiple tumorigenic processes. In addition to traditional pathways EGFR signaling, translocates nucleus acts as transcription factor proliferation cancer cells. Heregulin is known both an ErbB3 ErbB4 ligand. This study aimed investigate expression heregulin its relevant members well their phosphorylated forms human colorectal (CRC) tissues determine relationship...
While a cAMP-dependent protein kinase (protein A) has been suggested to phosphorylate epidermal growth factor (EGF) receptor in vitro, both intrinsic and EGF- or potent phorbol tumor promoter-induced phosphorylation of EGF were found be depressed human epidermoid carcinoma A431 cells by prior incubation the with various A activators (e.g. cholera toxin, forskolin, cAMP analogues, combination prostaglandin E1 3-isobutyl-1-methylxanthine). Protein did not change significantly either number...
Pyogenic granuloma is a lobular capillary hemangioma that occurs mostly on the skin, and occasionally mucosal surface of oral cavity, but very rarely in gastrointestinal tract. We report case 63‐year‐old woman who suffered from palpitations, iron deficiency anemia for 5 years. Esophagogastroduodenoscopy colonoscopy could not reveal significant bleeding focus. She had received medical treatment except iron. Capsule endoscopy revealed focus small intestine. Afterwards, we carried out double...
PURPOSE Limited information is available regarding the characteristics and outcomes of stage IV small bowel adenocarcinoma (SBA) in Japan. This study examined clinical pathological according to treatment strategies patients with SBA. METHODS retrospective observational used data jejunal or ileal collected by Small Bowel Malignant Tumor Project Japanese Society for Cancer Colon Rectum. Descriptive statistics were expressed as mean (standard deviation) median (range). Survival analysis was...
The clinicopathological features and prognosis of primary small bowel adenocarcinoma (PSBA), excluding duodenal cancer, remain undetermined due to its rarity in Japan.
Background This study aimed to compare the markers of potential pancreatic injury during antegrade double-balloon endoscopy (DBE) using newly developed ultrathin EN-580XP system and conventional EN-580T system. Methods Patients who were scheduled for DBE daily clinical practice enrolled. Clinical background, adverse events, laboratory data patients compared between those underwent in whom was used. The primary end points hyperamylasemia hyperlipasemia after DBE. Results A total 295 cases...
Background and Aim: Helicobacter pylori infection is a primary cause of gastroduodenal ulcers. To investigate whether there an association between H. small intestinal mucosal injury. Methods: Patients were selected from general pool subjects who underwent capsule endoscopy for current or past obscure gastrointestinal bleeding. Characteristics including age, gender, history, treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) and/or acid suppressant, diagnosis, investigated. infected...