A5091341412- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Genetic factors in colorectal cancer
- Inflammatory Bowel Disease
- Hip and Femur Fractures
- Helicobacter pylori-related gastroenterology studies
- Pelvic and Acetabular Injuries
- Metastasis and carcinoma case studies
- Renal Diseases and Glomerulopathies
- Spinal Fractures and Fixation Techniques
- Gastrointestinal Bleeding Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Eosinophilic Esophagitis
- Immunodeficiency and Autoimmune Disorders
- Hip disorders and treatments
- Bone fractures and treatments
- Microscopic Colitis
- Orthopaedic implants and arthroplasty
- Biliary and Gastrointestinal Fistulas
- Orthopedic Surgery and Rehabilitation
- Diverticular Disease and Complications
- Spine and Intervertebral Disc Pathology
- Mast cells and histamine
Kyushu University
2020-2025
Kagawa Prefectural Central Hospital
2020-2025
Iwate Medical University
2015-2024
Yamaguchi University
2022-2024
Fukuoka University
2022
The Japanese Society of Gastroenterological Surgery
2020
Showa University
2020
Jikei University School of Medicine
2020
Showa University Koto Toyosu Hospital
2020
Osaka University Hospital
2018-2019
The involvement of adhesion molecules in the glomerular accumulation inflammatory cells and subsequent injury was examined WKY rats with nephrotoxic serum nephritis. This model is characterized by early infiltration CD8-positive NK cells, followed influx monocytes/macrophages into glomeruli. At day 1 later, up-regulated expression intercellular molecule-1 (ICAM-1) observed exclusively endothelial association monocytes/macrophages. These expressed lymphocyte function-associated Ag-1 (LFA-1)....
The effect of vasopressin on subcellular localization AQP-CD and AQP3 water channels was examined in thirsted Brattleboro rats by immunohistochemistry immunoelectron microscopy. mainly present the cytoplasm collecting duct cells association with cytoplasmic vesicles but sparse apical membrane control vehicle-injected rats. In given 15 min before death, number immunogold particles for increased significantly (P < 0.002) from 1.8 +/- 0.2 to 10.0 0.4/microns a significant decrease 0.05)...
This study considers the use of deep learning to diagnose osteoporosis from hip radiographs, and whether adding clinical data improves diagnostic performance over image mode alone. For objective labeling, we collected a dataset containing 1131 images patients who underwent both skeletal bone mineral density measurement radiography at single general hospital between 2014 2019. Osteoporosis was assessed radiographs using five convolutional neural network (CNN) models. We also investigated...
Background and study aim Magnifying narrow-band imaging (M-NBI) is useful for the accurate diagnosis of early gastric cancer (EGC). However, acquiring skill at M-NBI takes substantial effort. An Internet-based e-learning system to teach endoscopic EGC using has been developed. This evaluated its effectiveness. Participants methods was designed as a multicenter randomized controlled trial. We recruited endoscopists participants from all over Japan. After completing Test 1, which consisted...
The mRNA expression and localization of the aquaporin (AQP) family in rat kidney were examined by ribonuclease protection assay immunohistochemistry. AQP1, AQP2, AQP3, AQP4 hardly detectable 16-day gestation fetuses. AQP1 was explosively expressed at 1 wk, keeping level throughout life. AQP2 apparently noticed 18-day fetuses enhanced gradually with age to reach a plateau 4 wk. AQP3 significantly found birth but not changed remarkably thereafter. protein appeared first apical side collecting...
Patients with rheumatoid arthritis (RA) are at high risk of developing cardiovascular disease, infections and malignancies during their lifetime, lymphoma being the most common malignancy. These patients may clinically present a wide spectrum lymphoid proliferations or lymphomas, which called lymphoproliferative disorders (LPD). The prediction sites LPD can be divided into nodal extranodal lesions, majority lesions. lesions especially in RA receiving methotrexate (MTX) pharynx, liver,...
ABSTRACT A 21-year-old man with a developmental disability presented for management of upper abdominal pain and vomiting. He was diagnosed by endoscopy computed tomography-duodenography as having duodenal obstruction due to duplication. underwent endoscopic resection the blind end duplication discharged on ninth postoperative day. In follow-up 6 weeks after treatment, scope passed smoothly it found that an iatrogenic ulcer postendoscopic had healed. Duodenal is rare, few cases have been...
Background and Objectives: A few deep learning studies have reported that combining image features with patient variables enhanced identification accuracy compared image-only models. However, previous not statistically the additional effect of on This study aimed to evaluate osteoporosis ability by hip radiographs variables. Materials andMethods: We collected a dataset containing 1699 images from patients who underwent skeletal-bone-mineral density measurements radiography at general...
Abstract Objectives Artificial intelligence (AI) may be practical for image classification of small bowel capsule endoscopy (CE). However, creating a functional AI model is challenging. We attempted to create dataset and an object detection CE explore modeling problems assist in reading CE. Methods extracted 18,481 images from 523 procedures performed at Kyushu University Hospital September 2014 June 2021. annotated 12,320 with 23,033 disease lesions, combined them 6161 normal as the...
Periodontal disease is the leading cause of tooth loss, and an association between periodontal non-oral systemic diseases has been shown. Formation biofilm by pathogens such as Fusobacterium nucleatum, Porphyromonas gingivalis, Streptococcus mutans their resistance to antimicrobial agents are at root persistent chronic bacterial infections. The bactericidal effect far-ultraviolet (F-UV) light irradiation 222 nm on bacteria was assessed qualitatively quantitatively. disruption F-UV examined...
CD8-positive lymphocytes (CD8+ lym) and ICAM-1/LFA-1 interaction have been implicated in the glomerular accumulation of monocytes/macrophages (Mo/Mphi) crescent formation antiglomerular basement membrane (anti-GBM) glomerulonephritis WKY rats. In present study, role CD8+ lym expression ICAM-1 inflammatory cytokines as well Mo/Mphi glomeruli was examined by RNase protection assay immunofluorescence microscopy. apparent at 1 h markedly enhanced day 3 after an anti-GBM Ab injection parallel...
Background: Diffuse idiopathic skeletal hyperostosis (DISH) is a pathology characterized by enthesis ossification, but there have been few reports on epidemiological surveys. This report presents cross-sectional survey of DISH from thoracic to sacral spine in patients at the tertiary emergency medical center. Methods: The were divided into (+) group and (−) for retrospective comparative study. primary outcome measures frequency patient demographic data, secondary previous history (diabetes...
Rat mesangial cells selected by long-term culture of glomeruli exhibited a hill and valley appearance in the confluent state were stained with antibodies against vimentin desmin, suggesting that they are smooth muscle-like cells. The glycoconjugates produced metabolically labeled [35S]sulfate [3H]glucosamine extracted 4 M guanidine HCl containing 0.5% Triton X-100. radiolabeled separated on DEAE-Sephacel compared those synthesized same conditions. Of three major sulfated glycoconjugates,...
To determine appropriate fecal calprotectin cut-off values for the prediction of endoscopic and histologic remission in Japanese patients with ulcerative colitis (UC).We performed a cross-sectional observational study 131 UC measured levels by fluorescence enzyme immunoassay. The clinical activity was assessed partial Mayo score (PMS). Relapse defined as increase PMS 2 points or more stool frequency rectal bleeding subscore. activities were evaluated 50 within 2-mo period from sampling....
We aimed to investigate an association between clinicopathological features, including immunohistochemical mucin phenotypes, and magnifying chromoendoscopic findings with crystal violet staining (ME-CV) in non-ampullary duodenal epithelial tumors (NADETs).A total of 55 patients NADET were divided into 3 groups by phenotype: intestinal, gastrointestinal, or gastric. ME-CV classified 4 patterns: convoluted, leaf-like, reticular/sulciolar, pinecone. The features compared among the...