Atsushi Imagawa

ORCID: 0000-0002-2641-4995
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Metastasis and carcinoma case studies
  • Gastrointestinal Tumor Research and Treatment
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal disorders and treatments
  • Esophageal Cancer Research and Treatment
  • Esophageal and GI Pathology
  • Gastroesophageal reflux and treatments
  • Intestinal and Peritoneal Adhesions
  • Pancreatic and Hepatic Oncology Research
  • Lymphoma Diagnosis and Treatment
  • Eosinophilic Esophagitis
  • Viral-associated cancers and disorders
  • Biliary and Gastrointestinal Fistulas
  • Genetic factors in colorectal cancer
  • Anesthesia and Sedative Agents
  • Intensive Care Unit Cognitive Disorders
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Breast Lesions and Carcinomas
  • Cancer and Skin Lesions
  • Abdominal vascular conditions and treatments
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Pancreatic function and diabetes
  • Vascular Malformations and Hemangiomas
  • Neuroendocrine Tumor Research Advances

Mito Saiseikai General Hospital
2011-2024

Jikei University Kashiwa hospital
1990-2017

Okayama University
2005-2015

Kurashiki Central Hospital
2003-2015

Kagawa Prefectural Central Hospital
2015

Fukuyama Cardiovascular Hospital
2015

Okayama University Hospital
2015

Okayama University of Science
2014

Okayama Central Hospital
2006-2008

Tsuyama Chuo Hospital
2007-2008

Endoscopic submucosal dissection (ESD) is a new method for the curative treatment of early gastrointestinal neoplasms, which was developed in order to increase en bloc and R0 resection rate, especially lesions larger than 20 mm diameter. Drawbacks ESD include fact that it technically substantially more difficult procedure associated with higher perforation rate. A retrospective study therefore carried out analyze cases relation time success, these factors were correlated characteristics...

10.1055/s-2006-944716 article EN Endoscopy 2006-10-20

Sodium hyaluronate (SH) is a promising submucosal injection solution during endoscopic mucosal resection, but its high cost an obstacle to more widespread use. The aim of this study was identify appropriate low-cost SH by varying the molecular weight and mixing various solutions with it.The viscoelasticity first measured. concentrations two 1 % preparations different weights (800 kDa 1900 kDa) were adjusted 0.5 %, 0.25 0.125 using 0.9 %/3.75 normal saline (NS), 5 %/20 dextrose water (DW),...

10.1055/s-2004-814524 article EN Endoscopy 2004-07-01

Summary Background Although Helicobacter pylori infection is closely associated with gastric cancer development, follow‐up studies after H. eradication are still scarce. Aim To clarify the preventive effect of eradication, special attention to differences in according histology. Methods Patients who underwent therapy and were followed‐up endoscopically for at least 1 year analysed. The incidence factors development investigated. Results A total 1807 patients enrolled. Six 1519 eradicated...

10.1111/j.1365-2036.2007.03268.x article EN Alimentary Pharmacology & Therapeutics 2007-02-05

Small bowel adenocarcinoma (SBA) is a rare malignancy that accounts for 1–2% of gastrointestinal tumours. We investigated the clinical characteristics, outcomes, and prognostic factors primary SBA. retrospectively analysed characteristics courses 205 SBA patients from 11 institutions in Japan between June 2002 August 2013. The tumour was duodenum jejunum/ileum 149 (72.7%) 56 (27.3%) patients, respectively. Sixty-four (43.0%) with duodenal were asymptomatic most cases detected by...

10.1038/bjc.2017.338 article EN cc-by-nc-sa British Journal of Cancer 2017-10-05

Background and study aim Magnifying narrow-band imaging (M-NBI) is useful for the accurate diagnosis of early gastric cancer (EGC). However, acquiring skill at M-NBI takes substantial effort. An Internet-based e-learning system to teach endoscopic EGC using has been developed. This evaluated its effectiveness. Participants methods was designed as a multicenter randomized controlled trial. We recruited endoscopists participants from all over Japan. After completing Test 1, which consisted...

10.1055/s-0043-111888 article EN Endoscopy 2017-06-21

To analyze the clinical characteristics of patients with gastrointestinal bezoars and their response to therapy. Patients We retrospectively reviewed cases 19 diagnosed at Okayama University Graduate School Medicine, Dentistry Pharmaceutical Sciences or one 15 collaborating institutions between December 2004 August 2013. investigated epidemiology etiology by determining gender, age diagnosis, medical history, symptoms, complications, modalities used for treatments, outcomes bezoar location,...

10.2169/internalmedicine.53.2114 article EN other-oa Internal Medicine 2014-01-01

Betacellulin (BTC), a member of the epidermal growth factor family, is expressed predominantly in human pancreas and induces differentiation pancreatic acinar cell line (AR42J) into insulin-secreting cells, suggesting that BTC has physiologically important role endocrine pancreas. In this study, we examined vivo effect recombinant (rhBTC) on glucose intolerance morphology using new mouse model with induced by selective alloxan perfusion. RhBTC (1 microg/g body wt) or saline was injected...

10.2337/diabetes.49.12.2021 article EN Diabetes 2000-12-01

<b>Background and study aims: </b>The optimal method of perioperative management antiplatelet agents during endoscopic procedures that carry a high risk bleeding is still controversial. The aim this was to evaluate the safety continuing aspirin treatment these in an Asian population. <b>Patients methods: </b>A multicenter, prospective, observational cohort conducted at six volume endoscopy centers Japan. included patients thromboembolism who were regularly taking (e. g. thienopyridine...

10.1055/s-0034-1391354 article EN Endoscopy 2015-01-15

ABSTRACT Scheduled piecemeal resection has been actively conducted for granular type laterally spreading tumor (LST‐G) in Japan, as long a definite preoperative diagnosis is made. However, en bloc desirable depressed lesions (e.g. IIc lesion) well non‐granular (LST‐NG) since they have considerable high risk submucoasl invasion and require precise histopathological evaluation. Endoscopic submucosal dissection (ESD) developed the of mucosal tumors gastrointestinal tract widely applied...

10.1111/j.1443-1661.2004.00396.x article EN Digestive Endoscopy 2004-07-01

Background and Study Aim: We have previously reported that gastric ulcers artificially created by endoscopic submucosal dissection (ESD) would heal within 8 weeks regardless of size location. The details the healing process remain unclear, we aimed to clarify mechanism histopathological investigation. Patients Methods: 21 post-ESD were examined histopathologically, using surgically resected specimens from patients who had subsequently undergone gastrectomy due invasion and/or lymphovascular...

10.1055/s-2006-925166 article EN Endoscopy 2006-04-01

AIM:To investigate the capacity for 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) to evaluate patients with gastrointestinal lesions of follicular lymphoma. METHODS:This retrospective case series consisted 41 lymphoma and involvement who underwent 18F-FDG-PET endoscopic evaluations at ten different institutions between November 1996 October 2011.Data endoscopic, radiological, biological examinations performed were retrospectively reviewed from clinical records.A...

10.3748/wjg.v18.i44.6427 article EN cc-by-nc World Journal of Gastroenterology 2012-01-01

Propofol administration via a target-controlled infusion system with bispectral index monitoring (BIS/TCI system) is expected to prevent complications from sedation during complex and long endoscopic procedures. We evaluated the feasibility of setting BIS/TCI for non-anesthesiologist propofol (NAAP) submucosal dissection (ESD).From May 2009 February 2013, 250 patients esophagogastric neoplasms were treated ESD using NAAP. In TCI system, initial target blood concentration was set at 1.2...

10.1055/s-0034-1377519 article EN cc-by-nc-nd Endoscopy International Open 2014-11-17

The efficacy of gemcitabine (GEM) on unresectable pancreatic cancer has been reported. However, in elderly patients, severe toxicities are frequently observed. In this study we aimed to assess the low-dose GEM patients.We reviewed 68 patients (≥65 years) with cancer. Thirty-six were treated (600-800 mg/m(2); group), and other 32 received best supportive care (BSC group).Median survival was 7.6 2.3 months BSC groups, respectively. group, median period longer 24 showing partial response or...

10.1159/000330384 article EN Digestion 2011-01-01

The importance of enteroscopy examinations to investigate the entire length small intestines has been emphasized in follicular lymphoma patients with intestinal involvement. aim present study was determine current state examinations, including performance rate, and prevalence lesions a patient population Japan. A retrospective multicenter survey 17 institutions collected case information 110 gastrointestinal results were reviewed, order identify potential factors affecting rate enteroscopy,...

10.3892/ol.2015.3251 article EN Oncology Letters 2015-05-20

Abstract Background and Aim Although sporadic non‐ampullary duodenal adenoma is speculated to be precancerous lesion, the relationship between carcinoma remains unclear due their rarity. Previous studies on epithelial neoplasm (SNADEN) have mainly targeted superficial tumors, like early carcinoma. The clinicopathological features, including those of advanced carcinoma, remain poorly investigated. We assessed features SNADEN, focusing tumor location. Methods retrospectively collected data 410...

10.1111/jgh.14640 article EN Journal of Gastroenterology and Hepatology 2019-02-28

Non-curative endoscopic resection of T1 colorectal cancer (CRC) carries a substantial risk recurrence. However, previous studies have reported significant proportion cases in which the deep margin was positive for due to technical difficulties submucosal dissection (ESD). With advancement technology and techniques resulting reduction margins, it is important reassess long-term prognosis major factors recurrence negative margins.

10.1159/000538557 article EN Digestion 2024-01-01

A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions peripheral whitish edematous mucosa. Initial biopsy specimens taken from revealed insufficient numbers cells for histological diagnosis. Subsequent mucosa containing enlarged villi infiltration forming lymphoid follicles, which led us to appropriate This case indicates that endoscopists should take samples rather than in rare...

10.1155/2012/582607 article EN cc-by Case Reports in Medicine 2012-01-01
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