A5023301990- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Liver Diseases and Immunity
- Liver Disease and Transplantation
- Neuroendocrine Tumor Research Advances
- Gastroesophageal reflux and treatments
- IgG4-Related and Inflammatory Diseases
- Hepatitis C virus research
- Abdominal vascular conditions and treatments
- Diet, Metabolism, and Disease
- Cancer Genomics and Diagnostics
- Esophageal Cancer Research and Treatment
- Hepatitis B Virus Studies
- Metastasis and carcinoma case studies
- Gastrointestinal Bleeding Diagnosis and Treatment
Kawasaki Medical School
2016-2025
Kagoshima Medical Center
2025
University of Occupational and Environmental Health Japan
2023-2024
Liechtenstein Institute
2023
Weatherford College
2022
Okayama Prefecture
2015-2020
Kawasaki Hospital
2013-2017
Okayama University
2005-2015
Creative Research Enterprises (United States)
2015
Tokyo Metropolitan Komagome Hospital
2009
Background Endoscopic ultrasound-guided biliary drainage (EUS-BD) is considered to be an effective salvage procedure for failed endoscopic retrograde cholangiopancreatography in patients with unresectable malignant obstruction. The aim of this retrospective study was evaluate the efficacy and feasibility EUS-BD. Methods From November 2006 May 2012, a total 64 who underwent EUS-BD (44 EUS-guided choledochoduodenostomy [EUS-CDS] 20 hepaticogastrostomy [EUS-HGS]) at seven tertiary-care referral...
Abstract Background and Aim: Recently, the clinical biological differences between right‐ left‐sided colon cancers have been widely debated. However, close analyses of these differences, based on large‐scale studies, scarcely reported. Methods: A total 3552 consecutive Japanese colorectal cancer cases were examined investigated. Results: The proportion right‐sided was relatively high in patients aged less than 40 years (33%) more 80 (43%). 40–59 low (male 22% female 29%). In male increased...
Endoscopic submucosal dissection (ESD) is a new method for the curative treatment of early gastrointestinal neoplasms, which was developed in order to increase en bloc and R0 resection rate, especially lesions larger than 20 mm diameter. Drawbacks ESD include fact that it technically substantially more difficult procedure associated with higher perforation rate. A retrospective study therefore carried out analyze cases relation time success, these factors were correlated characteristics...
<b><i>Background: </i></b>Serum levels of hepatitis B virus (HBV) DNA are an important predictor the risk hepatocellular carcinoma (HCC) in patients with chronic HBV infection. However, little is known about whether high surface antigen (HBsAg) increase for HCC. <b><i>Methods: </i></b>We investigated 167 who were treated nucleos(t)ide analogues (NA) at least 2 years (median: 5.8 years, range: 2-13.1 years). Relationships between reduced HBsAg...
Objective: Amino acid imbalance is often found in patients with cirrhosis, and this associated insulin resistance. However, the mechanism underlying relationship between amino resistance remains unclear. We evaluated serum concentrations nonalcoholic fatty liver disease to determine if any of levels acids were biochemical markers fibrosis stage steatohepatitis (NASH). Methods: In 137 who underwent biopsy, plasma branched-chain (BCAA), tyrosine (Tyr), BCAA-to-Tyr ratio values determined using...
The reported incidence of adverse events (AEs) in endoscopic retrograde cholangiopancreatography (ERCP) varies between 2.5% and 14%. aim this study was to evaluate the severity AEs biliary ERCP specify risk factors preventive measures for post-ERCP pancreatitis (PEP).Patients with disease intact papilla were prospectively enrolled at 36 hospitals April 2017 March 2018. primary outcomes AEs.A total 16,032 procedures performed during period 3739 patients enrolled. overall 10.1% ERCP-related...
Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is an uncommon, low-grade, malignant tumor that predominantly affects older patients and often located around the eyelids. Diagnosing EMPSGC challenging because of its clinical imaging similarities to benign lesions such as epidermal cysts. This report presents two cases with ultrasound features resembling cystic were initially considered in differential diagnosis. For both cases, revealed hypoechoic masses posterior acoustic...
Patients with malignant pancreatobiliary neoplasm sometimes manifest duodenal obstruction and biliary stricture synchronously or metachronously. In this paper, we reviewed our experience technique for combined endoscopic stent placement ultrasonography (EUS)‐guided drainage. Between May 2007 September 2009, was performed on seven patients distal strictures obstructions. The clinical success rate of the procedure, complications, patency periods stents were retrospectively evaluated. Clinical...
Background. Diagnosis of non-alcoholic fatty liver disease (NAFLD) is limited by the need for biopsies. Serum cytokeratin 18 (CK-18) levels have been investigated as potential biomarkers presence NAFLD and steatohepatitis (NASH). Herein, we assessed correlation between CK-18 progression. Material methods. were estimated using M30 antibody enzyme-linked immunosorbent assay in 147 patients diagnosed with NAFLD. In 72 patients, progression was evaluated repeated biopsy, which conducted after...
Objective Stenting is an established endoscopic therapy for malignant gastric outlet obstruction (mGOO). The choice of stent (covered vs uncovered) has been examined in prior randomised studies without clear results. Design In a multicentre prospective study, we compared covered (CSEMS) with uncovered self-expandable metal stents (UCSEMS) patients mGOO; main outcomes were dysfunction and patient survival, subgroup analyses extrinsic intrinsic tumours. Results Overall survival was poor no...
Bile duct stones after hepaticojejunostomy are considered a troublesome adverse event. Although percutaneous transhepatic procedures using cholangioscopy is performed to treat these bile stones, peroral endoscopic procedure short, double-balloon enteroscope (sDBE) an alternative. This study aimed compare the immediate and long-term outcomes of both treatments for in patients who underwent prior hepaticojejunostomy.Between October 2001 May 2013, 40 consecutive were treated at tertiary care...
This study aimed to evaluate the age-specific characteristics, prognosis, and complications of patients with lean nonalcoholic fatty liver disease (NAFLD).Background factors (age, sex, diabetes, dyslipidemia, hypertension, PNPLA3 gene polymorphism), blood test results, histology findings, muscle mass, grip strength were investigated in 782 NAFLD who underwent biopsy. Prognosis compared among 549 nonlean or followed up for 6.5 years. Additionally, background factors, according age (≥60 years...
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic disease. The serum level soluble CD163 (sCD163), a macrophage activation marker, associated with tissue changes; however, its prognostic value unknown. Here, we determined utility sCD163 as marker for hepatocellular carcinoma (HCC) and NAFLD.This retrospective study obtained data regarding levels, histology, background factors NAFLD in 287 patients (men/women, 140/147; average age, 53 ± 14 years) who underwent...
Objectives: Overexpression of B Cell-activating factor (BAFF) is involved in autoimmunity, but little known about its role autoimmune pancreatitis (AIP). The aim this study was to investigate the BAFF diagnosis and pathogenesis AIP. Methods: Patients with AIP (n = 19) were compared 2 disease control groups (chronic [n 17] pancreatic cancer 15]) a healthy subject group 19). Serum levels assessed using an enzyme-linked immunosorbent assay. expressions receptor tissue patients estimated...
The prognostic factors associated with severe-to-fatal post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) remain unclear despite the extensive number of studies on PEP. In total, 3739 ERCP patients biliary disease an intact papilla and indicated for were prospectively enrolled at 36 centers from April 2017 to March 2018. Those acute diagnosed before ERCP, altered gastrointestinal anatomy, American Society Anesthesiologists (ASA) physical status > 4 excluded....