A5001987756- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Hemodynamic Monitoring and Therapy
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Dialysis and Renal Disease Management
- Magnesium in Health and Disease
- Biomarkers in Disease Mechanisms
- Neuropeptides and Animal Physiology
- Pain Management and Opioid Use
- Lung Cancer Diagnosis and Treatment
- Pediatric Pain Management Techniques
- Neonatal Respiratory Health Research
- HIV Research and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Endometrial and Cervical Cancer Treatments
- Heart Rate Variability and Autonomic Control
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cancer Treatment and Pharmacology
- Neurological Disorders and Treatments
Morinomiya University of Medical Sciences
2018-2024
Kitano Hospital
2020-2024
European Foundation for the Study of Chronic Liver Failure
2021
Himeji Dokkyo University
2012-2019
Nagasaki University
2004-2007
Sendai Kousei Hospital
2006
Nagasaki Municipal Hospital
2003-2005
Citizens Specialty Hospitals
2003
Citizen (Japan)
2003
Takeda (Japan)
1991
The reported incidence of adverse events (AEs) in endoscopic retrograde cholangiopancreatography (ERCP) varies between 2.5% and 14%. aim this study was to evaluate the severity AEs biliary ERCP specify risk factors preventive measures for post-ERCP pancreatitis (PEP).Patients with disease intact papilla were prospectively enrolled at 36 hospitals April 2017 March 2018. primary outcomes AEs.A total 16,032 procedures performed during period 3739 patients enrolled. overall 10.1% ERCP-related...
Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most serious adverse event of ERCP. Therefore, it important to identify high-risk patients who require prophylactic measures. The aim this study was develop a practical prediction model for PEP that identifies patients.Patients underwent ERCP at three tertiary hospitals between April 2010 and September 2012 were enrolled. dataset divided into training set (two centers) validation (one center). Using set,...
Despite increased risk for coronary artery disease and acute myocardial infarction (AMI), prior studies have found that smokers with AMI lower mortality rates than nonsmokers, a phenomenon often termed 'smoker's paradox'. The present study was designed to examine the etiology of paradox', especially respect association inflammation. subjects included 528 consecutive patients who were admitted within 24 hours onset underwent successful intervention. Of subjects, 232 (44%) smokers. cardiac...
Although cardiogenic shock (CS) is the leading cause of death for acute myocardial infarction (AMI) patients, reliable predictive factors in stage, such as cardiovascular peptides, have not yet been identified.In 42 consecutive AMI patients with CS on admission, successfully treated by primary percutaneous coronary intervention (PCI) within 12 h onset, related including brain natriuretic peptide (BNP), atrial (ANP), renin, aldosterone, catecholamines, and adrenomedullin, were investigated 24...
Objective The object of our study was to identify the most useful predictor patient prognosis in acute myocardial infarction (AMI), from 7 acute-phase cardiovascular peptides which take part neurohumoral activation [brain natriuretic peptide (BNP), atrial (ANP), renin, aldosterone, adrenomedullin, epinephrine and norepinephrine]. Methods In 141 consecutive AMI patients, 24 hours onset, we evaluated plasma concentration levels types relationships between values these short-term clinical...
Background The relationship between plasma levels of serum amyloid A protein (SAA) concentrations and clinical course (including mortality) was investigated in patients with acute myocardial infarction (AMI). Methods Results study enrolled 280 consecutive AMI who were admitted within 10 h onset successfully reperfused by primary percutaneous coronary intervention. Plasma SAA evaluated at 24 after onset. threshold the upper quintile (325 μg/dl) used to divide into 2 groups: either a high (H...
The aim of the present study was to investigate relationship between plasma concentrations endothelin (ET)-1 and clinical outcome (including mortality) left ventricular (LV) systolic function in acute myocardial infarction (AMI).The group comprised 110 consecutive first-AMI patients who were successfully reperfused by primary coronary intervention. Plasma ET-1 evaluated 24 h from onset divided into 2 groups according median value, either a high (H group: > or = 2.90 pg/ml ET-1; n 55) low (L...
Whether young cervical cancer patients have poorer prognosis compared to older ones has remained controversial over the past half century. The last three decades seen a rise in morbidity and mortality among Japanese women with cancer. This reflects fact that importance of prevention not been fully recognized due limited clinical studies. We examined relationship between age cancer.We retrospectively medical records consecutive International Federation Gynecology Obstetrics stage IB IIB at...
The predictors of cardiac rupture (CR) in patients with acute myocardial infarction (AMI) treated successful primary coronary angioplasty have not been identified.Of 433 consecutive AMI subjects who underwent reperfusion by within 24 h onset, CR occurred 11 (2.5%), free wall 9, and ventricular septal perforation 2. Rates females, diabetes mellitus anterior were higher the group than others (p < 0.05). There no significant differences between 2 groups terms left (LV) function soon after...
Pancreatic metastases (PMs) account for 1% to 2% of pancreatic tumors, and their prognostic significance is poorly defined. We evaluated the incidence clinical characteristics primary tumors defined factors.This retrospective study 39 Japanese tertiary referral hospitals (January 2005 August 2015) analyzed patient tumor survival time. Kaplan-Meier analysis Cox proportional hazards models were applied evaluate overall factors, respectively.We enrolled 159 patients with a pathologic diagnosis...
Some colorectal cancer patients harboring FGFR (fibroblast growth factor receptor) genetic alterations, such as copy number gain, mutation, and/or mRNA overexpression, were selected for enrollment in several recent clinical trials of inhibitor, because these alterations preclinically reported to be associated with inhibitor sensitivity well poor prognosis, invasiveness, metastatic potential. However, few enrolled responsive inhibitors. Thus, practical strategies are eagerly awaited that can...
Trigeminal neuralgia (TN) occasionally affects older adults, frequently worsens, and becomes refractory to medication. Older adult patients with TN may consider microvascular decompression (MVD) for their treatment. No study examines MVD effects on patients' health-related quality of life (HRQoL). The present evaluates the HRQoL aged 70 years before after MVD.Adult who underwent evaluated using 36-Item Short-form (SF-36) Health Survey 6 months MVD. were divided into four groups according...
Abstract Objectives The condition of air bubbles in the large intestine is an influential factor for good quality colonoscopy. However, correlative factors severity during colonoscopy are not established. Therefore, this study aimed to elucidate influencing intestine. Materials and Methods A total 314 examinees who underwent between August September 2022 were enrolled (median age [range], 65 [18–88] years). Air scored using Colon Endoscopic Bubble Scale (CEBuS) clinical associated with CEBuS...
Background Experimental evidence indicates that magnesium sulfate may have potential cardioprotective properties as an adjunct to coronary reperfusion. The present study was designed examine the hypothesis might beneficial effects on left ventricular (LV) function and microvascular in patients with acute myocardial infarction (AMI). Methods Results population of 180 consecutive a first AMI (anterior or inferior) underwent successful primary intervention. Patients were randomized treatment...
It has recently been suggested that virtual-assisted lung mapping may enable safer and more reliable intraoperative navigation compared to conventional preoperative marking strategies. This study aimed examine the relationship between emphysematous lungs visibility of markings.We retrospectively analyzed data 21 patients who underwent followed by resection October 2013 May 2015. The markings was graded. degree pulmonary emphysema assessed percentage low attenuation area on computed...
The aim of the present study was to identify relationship between sub-acute stent thrombosis (SAT) and acute-phase inflammatory reactants, such as high-sensitivity C-reactive protein (hs-CRP) serum amyloid-A (SAA), in patients with acute myocardial infarction (AMI) successfully treated primary coronary stenting.The 381 consecutive AMI subjects were reperfused by stenting within 24 h onset. SAT confirmed angiographically 10 (2.6%). There no significant differences or without terms patient...
Our study was planned to investigate the relationship between plasma levels of serum amyloid A protein (SAA) concentrations and subsequent left ventricular systolic function in patients with acute myocardial infarction (AMI) treated primary coronary angioplasty.Reperfusion by percutaneous intervention successful 486 consecutive AMI who were admitted within 12 hours onset. Plasma SAA evaluated 24 after Left (LV) serially determined ventriculography performed (soon recanalization) chronic...
The objective of the present study was to compare left ventricular (LV) function and clinical outcomes in diabetics versus nondiabetics with acute myocardial infarction (AMI) treated by primary coronary angioplasty. A total 327 consecutive AMI subjects were reperfused angioplasty within 12 hours from onset. Diabetes mellitus (DM) 104 patients. LV serially determined ventriculograms taken chronic phases (6 months after onset). (I) early ST-segment resolution rate lower DM patients compared...
Contrary to other developed countries, in Japan, recent years have seen increases cervical cancer incidence and mortality among young people. However, the human papillomavirus (HPV) vaccine program, a key measure for avoiding cancer, has been virtually suspended. Temporal changes profiles this unique situation not fully investigated epidemiologically. Our study aimed determine current status future trends of precancerous lesions Japan. Mortality rates during 1975 2016 intraepithelial...