- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Neuroendocrine Tumor Research Advances
- Pancreatitis Pathology and Treatment
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Biliary and Gastrointestinal Fistulas
- Lung Cancer Research Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Genomics and Diagnostics
- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Renal cell carcinoma treatment
- Cancer Diagnosis and Treatment
- Hepatitis C virus research
- Medical Imaging and Pathology Studies
- Hepatitis B Virus Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- IgG4-Related and Inflammatory Diseases
- Colorectal and Anal Carcinomas
- Metastasis and carcinoma case studies
Teine Keijinkai Hospital
2014-2024
Kameda Medical Center
2020
Sapporo Science Center
2019
Shizuoka Cancer Center
2017
The Japanese Society of Gastroenterological Surgery
2016
The University of Tokyo
2014
Tokai University
2014
JR Tokyo General Hospital
2011-2012
Japan Pancreatic Disease Research Foundation
2009-2012
Kagawa University Hospital
2011-2012
Since 1981, the Japan Pancreas Society has been hosting a nationwide pancreatic cancer registry. To commemorate its 30th anniversary, we review history and latest achievement.During 3 decades, more than 350 leading institutions in contributed voluntarily to register periodic follow-up. The registry was modified protect privacy by encrypting hash algorithm.From 1981 2007, 32,619 cumulative records were analyzed. overall survival of invasive improved significantly. More patients with earlier...
// Kei Mitsuhashi 1 , Katsuhiko Nosho Yasutaka Sukawa 2 Matsunaga Miki Ito Hiroyoshi Kurihara Shinichi Kanno Hisayoshi Igarashi Takafumi Naito Yasushi Adachi Mami Tachibana Tokuma Tanuma 1, 3 Hiroyuki Maguchi Toshiya Shinohara 4 Tadashi Hasegawa 5 Masafumi Imamura 6 Yasutoshi Kimura Koichi Hirata Reo Maruyama 7 Hiromu Suzuki Kohzoh Imai 8 Yamamoto 9, * Yasuhisa Shinomura Department of Gastroenterology, Rheumatology and Clinical Immunology, Sapporo Medical University School Medicine, Sapporo,...
BACKGROUND: Five cases of transfusion transmission hepatitis E virus (HEV) have been reported so far. The infection routes the causative donors remain unclear, however. Also, progress markers in entire course HEV has not well documented. STUDY DESIGN AND METHODS: Nucleic acid testing was performed by real‐time reverse transcription–polymerase chain reaction targeting open reading frame 2 region HEV. Full‐length nucleotide sequences RNA were detected direct sequencing. RESULTS: Lookback study...
Pancreatic ductal adenocarcinoma (PDAC) may derive from an intraductal papillary mucinous neoplasm (IPMN) of the pancreas or develop in pancreatic duct apart IPMN. The purpose this study was to define clinicopathological features these 2 entities and compare them with those ordinary PDAC.Of 765 patients who had surgical resection for IPMN, 122 were diagnosed as having PDAC derived IPMN 31 concomitant In addition, 7605 registered Japan Pancreas Society cancer registry compared above...
Purpose: Patients with pancreatic neuroendocrine neoplasm grade-3 (PanNEN-G3) show variable responses to platinum-based chemotherapy. Recent studies indicated that PanNEN-G3 includes well-differentiated tumor G3 (NET-G3). Here, we examined the clinicopathologic and molecular features of assessed responsiveness chemotherapy survival.Experimental Design: A total 100 patients were collected from 31 institutions, after central review characteristics each histologic subtype [NET-G3 vs. carcinoma...
The Japanese Society of Hepato-Biliary-Pancreatic Surgery launched the clinical practice guidelines for management biliary tract cancers (cholangiocarcinoma, gallbladder cancer, and ampullary cancer) in 2007, then published 2nd version 2014.In this 3rd version, questions (CQs) were proposed on six topics. recommendation, grade statement each CQ discussed finalized by an evidence-based approach. Recommendations graded as Grade 1 (strong) or 2 (weak) according to concepts Grading Assessment,...
The aim of this study was to evaluate the long-term follow-up results patients with branch duct intraductal papillary mucinous neoplasms (BD-IPMNs) without mural nodules (MNs) at 10 representative institutions in Japan.We analyzed 349 BD-IPMN who had no MNs on endoscopic ultrasonography initial diagnosis.Observation periods ranged from 1 16.3 years (median, 3.7 years). Sixty-two (17.8%) exhibited disease progression during follow-up. Twenty-two underwent surgery, leading a pathological...
Only a few studies have evaluated the long-term effects of nonalcoholic fatty liver disease (NAFLD) on type 2 diabetes mellitus (T2DM), and none examined whether NAFLD improvement reduces T2DM incidence. We investigated association between incidence.Between 2000 2012, 4,604 participants who underwent health check twice with >10 years were enrolled. Exclusion criteria positive hepatitis B surface antigen, C antibody, ethanol intake >20 g/day, diabetes. The 3,074 eligible divided into an group...
Objectives There have been only a few reports on follow-up results of serous cystic neoplasm (SCN) the pancreas. The frequency malignancy and surgical indication SCN are not determined yet. Methods In this multi-institutional study Japan Pancreas Society, total 172 patients with were enrolled. mean period was 4.5 years. Surgical resection performed in 90 patients, whereas remaining 82 simply observed. Results Of all 20% symptomatic. tumor located pancreatic head (39%), body (35%), tail...
The present study was a retrospective investigation of predictors malignancy in intraductal papillary mucinous neoplasm (IPMN) the pancreas.The subjects were 310 patients who underwent pancreatic resection at 3 high-volume centers. Preoperative laboratory and imaging findings analyzed logistic regression analyses. Endoscopic ultrasonography measurements essential for size mural nodules, central review conducted pathological diagnosis.Pathological diagnosis benign IPMN 150 cases malignant 160...
Background: No study has compared covered metallic stents with Tannenbaum stents. We evaluated the efficacy of DoubleLayer stent (DLS) and Covered Wallstent (CWS) in patients pancreatic head cancer (PHC). Patients & Methods: This was a multicenter, prospective randomized study. Between October 2005 December 2007, we enrolled 113 (58 DLS, 55 CWS) unresectable PHC distal biliary obstructions observed them for at least 6 months. Results: significant difference patient survival found between...
Background and study aims Short-type single-balloon enteroscope (short SBE)-assisted endoscopic retrograde cholangiopancreatography (ERCP) is a promising alternative treatment in postsurgical altered anatomy. However, it technically demanding, factors affecting its technical difficulty have not yet been clarified. This aimed to examine the procedural success rate of short SBE-assisted ERCP potential failure. Patients methods A total 117 consecutive patients (203 procedures) with surgically...
Despite the development of peroral video cholangioscopy (PVCS), no prospective multicenter studies have been undertaken to investigate diagnostic accuracy PVCS in biliary tract diseases. Therefore, aim this study was clarify evaluating lesions.This a at five tertiary referral centers Japan and included 87 eligible patients with diseases who underwent PVCS. The evaluated ability diagnose indeterminate diseases, detect mucosal cancerous extension preoperatively extrahepatic bile duct cancers,...