A5011924949- Intracranial Aneurysms: Treatment and Complications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Cerebrovascular and Carotid Artery Diseases
- Gallbladder and Bile Duct Disorders
- Moyamoya disease diagnosis and treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Pediatric Hepatobiliary Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Liver Disease and Transplantation
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Neuroendocrine Tumor Research Advances
- Nuclear Physics and Applications
- Neurological Complications and Syndromes
- Multiple and Secondary Primary Cancers
- Liver Disease Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Viral-associated cancers and disorders
- Renal cell carcinoma treatment
- Pancreatitis Pathology and Treatment
- Cancer Diagnosis and Treatment
Teikyo University Chiba Medical Center
2018-2024
Tohoku University
2010-2023
Okayama University
2023
Miwa Hospital
2023
Nagoya University
2018-2022
Yotsuya Medical Cube
2022
Tokyo Medical and Dental University
2022
High Energy Accelerator Research Organization
2007-2022
Chiba University
2011-2021
Moscow Institute of Physics and Technology
2021
Diffusion-weighted MR images were compared with T2-weighted and correlated 1H spin-echo 31P spectroscopy for 6-8 h following a unilateral middle cerebral bilateral carotid artery occlusion in eight cats. using strong gradient strengths (b values of 1413 s/mm2) displayed significant relative hyperintensity ischemic regions as early 45 min after onset ischemia whereas failed to clearly demonstrate brain injury up 2-3 postocclusion. Signal intensity ratios (SIR) normal tissues greater the...
Abstract The sensitivity of diffusion‐weighted MRI was compared to that T2‐weighted following temporary middle cerebral artery occlusion (MCA‐0) for 33 min followed by 4 h reperfusion in rats. Diffusion‐weighted spin‐echo images using strong gradients ( b value 1413 s/mm 2 ) demonstrated a significant increase signal intensity ischemic regions as early 14 after onset ischemia comparison the normal, contralateral hemisphere p < 0.05). This hyperintensity returned baseline levels during...
The Japanese Society of Hepato-Biliary-Pancreatic Surgery launched the clinical practice guidelines for management biliary tract cancers (cholangiocarcinoma, gallbladder cancer, and ampullary cancer) in 2007, then published 2nd version 2014.In this 3rd version, questions (CQs) were proposed on six topics. recommendation, grade statement each CQ discussed finalized by an evidence-based approach. Recommendations graded as Grade 1 (strong) or 2 (weak) according to concepts Grading Assessment,...
The results of surgical treatment for intrahepatic cholangiocarcinoma (ICC) and specific factors influencing survival are still unclear.Between 1984 2001, 62 patients with ICC underwent laparotomy, a 77 per cent (48 patients) resectability rate. tumours in these 48 were reviewed retrospectively to examine the relationship between gross appearance (mass forming, periductal infiltrating, intraductal growth, mass forming plus infiltrating) patient survival, as well manner recurrence. In...
Diffusion-weighted magnetic resonance (MR) images from rats during acute cerebral ischemia induced by middle artery occlusion were analyzed for correspondence with changes in brain water, cation concentrations, and Na + ,K -ATPase activity measured vitro after 30 or 60 min of ischemia. In the ischemic hemisphere, signal intensity was increased at (p < 0.05 vs contralateral hemisphere) further min. 34% lower cortex 40% basal ganglia 0.05), but water content K concentrations not...
PURPOSE: Hepatic resection affords the best hope of survival for patients with colorectal carcinoma metastatic to liver. However, recurrences are observed in about 60 percent after curative hepatic resection. The purpose this study was examine prognostic factors undergoing metastases. METHODS: Between April 1984 and September 1997, 168 underwent clinicopathologic studied value were gender, age, primary site, nodal status tumor, time metastases, preoperative serum level carcinoembryonic...
BACKGROUND: Superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis prevents ischemic attack by improving blood flow in patients with occlusive cerebrovascular disease and hemodynamic compromise. Recent evidence suggests that focal hyperperfusion is a potential complication of this procedure for moyamoya disease. OBJECTIVE: To clarify the exact differences incidence clinical manifestations phenomenon between without METHODS: N-isopropyl-p-[123I]iodoamphetamine single-photon...
Although fibroblast growth factor 19 (FGF19) can promote liver carcinogenesis in mice, its involvement human hepatocellular carcinoma (HCC) has not been well investigated. FGF19, a member of the FGF family, unique specificity for receptor FGFR4. This study aimed to clarify FGF19 development HCC.We investigated and FGFR4 expression 40 specimens using quantitative real-time reverse transcription polymerase chain reaction (RT-PCR) analysis immunohistochemistry. Moreover, we examined...
Pancreatic cancer has one of the highest mortalities among all malignancies and there is an urgent need for new therapy. This might be achieved by resolving detailed biological mechanism, in this study we examined how pancreatic cells develop aggressive properties focusing on signalling through fibroblast growth factor (FGF)10 FGF receptor (FGFR)2, which play important roles organogenesis. Immunostaining tissues showed that FGFR2 was expressed cells, whereas FGF10 stromal surrounding cells....
<i>Background:</i> Cerebral hyperperfusion is a potential complication of superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis for moyamoya disease, but the optimal postoperative management has not been determined. Aggressive blood pressure lowering controversial because risk ischemic complications. <i>Objective:</i> To establish protocol to prevent symptomatic in disease. <i>Methods:</i>...
Cerebral hyperperfusion (CHP) is a potential complication of superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis for moyamoya disease (MMD), and optimal postoperative management has not yet been established. Minocycline, neuroprotective antibiotic agent, plays role in blocking matrix metalloproteinase 9 (MMP-9), which contributes to edema formation hemorrhagic conversion after ischemia-reperfusion. Patients with MMD have shown increased serum MMP-9 levels.To examine the...
<b><i>Background:</i></b> Cerebral aneurysms carry a high risk of rupture and so present major threat to the patient’s life. Accurate criteria for predicting aneurysm are important therapeutic decision-making, some clinical morphological factors may help predict unruptured aneurysms, such as sex, size location. Hemodynamic forces considered be key in natural history cerebral but effect on is uncertain, whether low or wall shear stress (WSS) most critical promoting...
The violation of Baryon Number, $\mathcal{B}$, is an essential ingredient for the preferential creation matter over antimatter needed to account observed baryon asymmetry in universe. However, such a process has yet be experimentally observed. HIBEAM/NNBAR %experiment program proposed two-stage experiment at European Spallation Source (ESS) search number violation. will include high-sensitivity searches processes that violate by one or two units: free neutron-antineutron oscillation...