A5051229147- Gastric Cancer Management and Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Metastasis and carcinoma case studies
- Diverticular Disease and Complications
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Tracheal and airway disorders
- Eosinophilic Esophagitis
- Anorectal Disease Treatments and Outcomes
- Dysphagia Assessment and Management
- Surgical Sutures and Adhesives
- Microscopic Colitis
- Genetic factors in colorectal cancer
- Pancreatitis Pathology and Treatment
- Hospital Admissions and Outcomes
- Surgical Simulation and Training
- Inflammatory Bowel Disease
- IgG4-Related and Inflammatory Diseases
- Power Transformer Diagnostics and Insulation
Nippon Medical School
2015-2025
Nippon Medical School Hospital
2021-2023
University Gastroenterology
2023
American Society for Gastrointestinal Endoscopy
2022
Chiba Hokusou Hospital
2020
Kameda Medical Center
2010
INTRODUCTION: The bleeding source of hematochezia is unknown without performing colonoscopy. We sought to identify whether colonoscopy a risk-stratifying tool etiology and predict outcomes presenting symptoms can differentiate the etiologies in patients with hematochezia. METHODS: This multicenter retrospective cohort study conducted at 49 hospitals across Japan analyzed 10,342 admitted for outpatient-onset acute RESULTS: Patients were mostly elderly population, 29.5% had hemodynamic...
Abstract Background Direct and indirect clipping treatments are used worldwide to treat colonic diverticular bleeding (CDB), but their effectiveness has not been examined in multicenter studies with more than 100 cases. Objective We sought determine the short‐ long‐term of direct versus for CDB a nationwide cohort. Methods studied 1041 patients who underwent ( n = 360) or 681) at 49 hospitals across Japan (CODE BLUE‐J Study). Results Multivariate analysis adjusted age, sex, important...
Background The rebleeding risks and outcomes of endoscopic treatment for acute lower gastrointestinal bleeding (ALGIB) may differ depending on the location, type, etiology stigmata recent hemorrhage (SRH) but have yet to be fully investigated. We aimed identify high risk SRH propose an optimal strategy. Methods retrospectively analyzed 2699 ALGIB patients with at 49 hospitals (CODE BLUE-J Study), whom 88.6 % received treatment. Results 30-day rates untreated significantly differed among...
Background and study aim: The technical difficulty of endoscopic submucosal dissection (ESD) for colorectal neoplasms has not been resolved. Water pressure method (WPM) are helpful techniques to overcome ESD procedure. We evaluated the efficacy safety with WPM (WPM-ESD) compared conventional (C-ESD). Patients methods: This was a single-center retrospective observational study. 311 lesions were allocated into WPM-ESD C-ESD groups, which before after propensity score matching. main outcomes...
Abstract Background It is unclear whether prophylactic endoscopic closure after colorectal submucosal dissection (ESD) reduces the risk of postoperative adverse events due to variability in lesion characteristics. Therefore, we conducted a retrospective study using propensity score matching evaluate efficacy clip preventing ESD. Methods This single-center cohort included 219 neoplasms which were removed by The patients allocated into and non-closure groups, compared before propensity-score...
Currently, large, nationwide, long-term follow-up data on acute lower gastrointestinal bleeding (ALGIB) are scarce. We investigated risks of recurrence after hospital discharge for ALGIB using a large multicenter dataset.
The study aimed to identify prognostic factors for patients with acute lower gastrointestinal bleeding and develop a high-accuracy prediction tool. analysis included 8254 cases of hematochezia who were admitted urgently based on the judgment emergency physicians or gastroenterology consultants (from CODE BLUE J-study). Patients randomly assigned derivation cohort validation in 2:1 ratio using random number table. Assuming that present at time admission are involved mortality within 30 days...
Goals: The aim is to elucidate the efficacy and safety of double-balloon endoscopy (DBE) for small bowel capsule (SBCE) retrieval from stricture follow outcome where SBCE was entrapped. Background: retention a serious adverse event most retained capsules are retrieved by surgery. There still no report analyzing follow-up patients with after entrapped SBCEs DBE. Methods: This study designed retrospective cohort study. Subjects were 12 consecutive attempted using Success rate DBE, surgical...
Background and AimsWe aimed to determine the optimal timing of colonoscopy factors that benefit patients who undergo early for acute lower GI bleeding.MethodsWe identified 10,342 with hematochezia (CODE BLUE-J study) admitted 49 hospitals in Japan. Of these, 6270 underwent a within 120 hours were included this study. The inverse probability treatment weighting method was used adjust baseline characteristics among (≤24 hours, n = 4133), elective (24-48 1137), late (48-120 1000) colonoscopy....
Introduction Indigo naturalis (IN) is a blue pigment extracted from Assam indigo and other plants has been confirmed to be highly effective for ulcerative colitis (UC) treatment in several clinical studies. Objective We conducted multicenter double-blind study confirm the efficacy safety of short-term IN administration. Methods A multicenter, randomized controlled trial was between December 2015 October 2018 our facilities. Forty-six patients with mild moderate active UC (Lichtiger index:...
Abstract Endoscopic hand suturing (EHS) was first developed to firmly close a mucosal defect following endoscopic submucosal dissection and has the potential for expanded applications. This study aimed investigate feasibility safety of EHS in various clinical settings. In this single-center pilot study, 15 patients who had diseases with indications were prospectively recruited. Technical success, success after procedure, severe EHS-related adverse events (AEs) evaluated. applied closure...
Ligation therapy, including endoscopic detachable snare ligation (EDSL) and band (EBL), has emerged as an treatment for colonic diverticular bleeding (CDB); its comparative effectiveness risk of recurrent remain unclear, however. Our goal was to compare the outcomes EDSL EBL in treating CDB identify factors after therapy.We reviewed data 518 patients with who underwent (n = 77) or 441) a multicenter cohort study named Colonic Diverticular Bleeding Leaders Update Evidence From Multicenter...
Linked color imaging (LCI) improves detection of colorectal neoplastic lesions during colonoscopy. However, polyps <5 mm in diameter often do not require resection, and the benefits LCI are unclear for ≥5 that indicated endoscopic resection clinical practice. This randomized controlled trial compared rates adenoma polyps, stratified by size, white light (WLI).We ADR (5 mm-) PDR mm-), which were defined as proportion patients with at least one or polyp a 5 larger WLI groups. Moreover, we...
Abstract Background The value of endoscopy for acute lower GI bleeding (ALGIB) remains unclear, given few large cohort studies. We aim to provide detailed clinical data ALGIB management and identify patients at risk adverse outcomes based on endoscopic diagnosis. Methods conducted a multicenter, retrospective study, named CODE BLUE J-Study, in 49 hospitals throughout Japan studied 10,342 cases admitted outpatient-onset hematochezia. Results Cases were mostly elderly, with 29.5% hemodynamic...
Abstract Background Endocytoscopy (ECS) aids early gastric cancer (EGC) diagnosis by visualization of cells. However, it is difficult for non-experts to accurately diagnose EGC using ECS. In this study, we developed and evaluated a convolutional neural network (CNN)-based system ECS-aided diagnosis. Methods We constructed CNN based on residual with training dataset comprising 906 images from 61 cases 717 65 noncancerous mucosa (NGM) cases. To evaluate diagnostic ability, used an independent...
Small bowel adenocarcinomas (SBAs) are rare and there is little comprehensive data on SBA genomic alterations for Asian patients. This study aimed to profile of in Japanese patients using targeted next-generation sequencing (NGS).We examined 22 surgical resections from with primary SBA. were analyzed by NGS. Mismatch repair (MMR) status was determined immunohistochemical analysis. Mucin phenotypes classified as gastric (G), intestinal (I), gastrointestinal (GI), null (N) types MUC2, MUC5AC,...
Gastric endoscopic full-thickness resection (EFTR) requires secure defect closure [1]. Here, we report a successful case of EFTR with hand suturing that provided double-layer [2] [3] [4].
Tumor size impacts the technical difficulty and histological curability of colorectal endoscopic submucosal dissection (ESD); however, preoperative evaluation tumor is often different from assessment. Analyzing influential factors on failure to obtain an accurate could help prepare optimal conditions for safer more reliable ESD.
Abstract Aims During intraoperative bleeding in endoscopic submucosal dissection (ESD), switching to spray coagulation may be beneficial compared with the continuous use of swift and can reduce need for hemostatic forceps. We retrospectively assessed effectiveness modes on during gastric ESD. Methods Results A total 316 events (156 Swift group 160 Spray group) were consecutively recorded. In group, hemostasis was performed using mode a retracted tip needle‐type knife, followed by treated...
Abstract Background and Aim While short long attachment caps are available for colonoscopy, it is unclear which type more appropriate stigmata of recent hemorrhage (SRH) identification in acute hematochezia. This study aimed to compare the performance versus hematochezia diagnoses outcomes. Methods We selected 6460 patients who underwent colonoscopy with from 10 342 cases CODE BLUE‐J study. performed propensity score matching (PSM) balance baseline characteristics between cap users. Then,...