A5109237147- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Vascular Malformations and Hemangiomas
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer-related gene regulation
- Anesthesia and Sedative Agents
- Lymphoma Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders
- Drug Transport and Resistance Mechanisms
- Intensive Care Unit Cognitive Disorders
- Nausea and vomiting management
- Hepatitis B Virus Studies
- Inflammatory Bowel Disease
- Diagnosis and treatment of tuberculosis
- Colorectal Cancer Screening and Detection
Nippon Medical School Hospital
2022
Nippon Medical School
2022
The Japanese Society of Gastroenterological Surgery
2015-2016
Toranomon Hospital
2010-2015
Jikei University School of Medicine
2004-2009
Tokyo Shinagawa Hospital
1998
University of Michigan–Ann Arbor
1996
Tachikawa Hospital
1992
Background and Study Aims: The narrow band imaging (NBI) system consists of a sequential electronic endoscope source light equipped with new filters, yielding very clear images microvessels on mucosal surfaces. aim this prospective study was to measure the correlation between magnified obtained NBI histological findings, especially regard vascular pattern. In addition, three-dimensional were reconstructed using laser scanning microscope. Patients Methods: Between July 2001 August 2003, 165...
Magnifying endoscopy combined with narrow-band imaging (ME-NBI) has been used for differential diagnosis of various focal lesions. The aim our study was to evaluate ME-NBI criteria cancer in superficial depressed gastric lesions comparison conventional white light (WLE).ME-NBI and WLE images 100 depressions (55 cancers, 45 benign depressions) were independently evaluated by 11 endoscopists blinded the each case. presence or absence predefined findings relating microvasculature fine mucosal...
Recently, the need for sedation in gastrointestinal endoscopy has been increasing. However, National Health Insurance Drug Price list Japan does not include any drug specifically used sedation. Although benzodiazepines are main medication, their use cases of approved. This led Gastrointestinal Endoscopy Society to develop first set guidelines on basis evidence-based medicine collaboration with Japanese Anesthesiologists. The present comprise 14 statements, five which were judged be valid...
Preliminary studies have suggested autofluorescence endoscopy (AFE) to be accurate in the diagnosis of gastric tumors. Our prospective blinded study systematically compared AFE with white light (WLE) for detection superficial neoplasia.An enriched population included 33 patients neoplasia referred endoscopic submucosal dissection (ESD), and 18 control undergoing follow-up after curative ESD. At direction a coordinator, two endoscopists who were patient's history each other's findings,...
Backgrounds. Magnifying endoscopy with narrow-band imaging (ME-NBI) has become essential for determining tumor margin in early gastric cancer (EGC). Here, we investigated the usefulness of ME-NBI assessment invasion depth EGC. Methods. For 119 patients who had undergone and en bloc resection by endoscopic submucosal dissection, three physicians prospectively examined high-magnification images clinical features such as presence or absence dilated vessels (D vessels). Cases D verified at least...
Although focal cancer occasionally coexists with gastric hyperplastic polyps, previous studies have reported that white light endoscopy (WLE) and biopsy sampling cannot effectively predict the coexistence of cancer. The aim this study was to elucidate efficacious predictors for coexistence.This retrospective single academic center analyzed consecutive patients polyps diagnosed as before endoscopic resection. Using an image catalog WLE magnifying combined narrow band imaging (ME-NBI)...
Abstract Background Endocytoscopy (ECS) aids early gastric cancer (EGC) diagnosis by visualization of cells. However, it is difficult for non-experts to accurately diagnose EGC using ECS. In this study, we developed and evaluated a convolutional neural network (CNN)-based system ECS-aided diagnosis. Methods We constructed CNN based on residual with training dataset comprising 906 images from 61 cases 717 65 noncancerous mucosa (NGM) cases. To evaluate diagnostic ability, used an independent...
H(+)-K(+)-adenosinetriphosphatase (H(+)-K(+)-ATPase) is the principal enzyme responsible for process of gastric acid secretion. This expressed in a cell-type-specific manner parietal cells. To explore mechanisms regulating its expression, we transfected differentiated canine cells primary culture with H(+)-K(+)-ATPase-luciferase reporter genes and assessed transcriptional activities. Deletional analysis 5'-flanking region this gene demonstrated remarkable increment activity associated...
The WEO Upper GI Cancer Committee, chaired by Professor Hisao Tajiri, has been instrumental in the development of a new algorithm for detection early gastric cancer. In particular, members Gastric Subcommittee, headed Mitsuru Kaise, actively participated research efforts that led to final version algorithm. cooperation between Japanese Gastroenterological Association (JGA), Gastrointestinal Endoscopy Society (JGES) and (JGCA), task force was put together initiated its activities 2013. main...
症例は69歳女性，便潜血陽性の精査目的で，下部消化管内視鏡検査が施行された。下部直腸に約3cm大の表面平滑な平皿状隆起性病変を認めた。生検病理組織所見にて，mucosa-associated lymphoid tissue（MALT）lymphomaが疑われ，経肛門的直腸腫瘍切除術を施行された。確定診断を得た1症例を経験したので文献的考察を加えて報告する。