A5034175904- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Anesthesia and Sedative Agents
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Neuropeptides and Animal Physiology
- Dysphagia Assessment and Management
- Diverticular Disease and Complications
- Helicobacter pylori-related gastroenterology studies
- Clinical Nutrition and Gastroenterology
- Child Nutrition and Feeding Issues
- Diabetes Treatment and Management
- Diet and metabolism studies
- Pancreatic function and diabetes
- Gastrointestinal Tumor Research and Treatment
- IgG4-Related and Inflammatory Diseases
- Metastasis and carcinoma case studies
- Gallbladder and Bile Duct Disorders
- Organometallic Complex Synthesis and Catalysis
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal motility and disorders
Showa Inan General Hospital
2016-2025
Iowa Digestive Disease Center
2018-2020
Teikyo University
2013-2016
Creative Research Enterprises (United States)
2016
The Japanese Society of Gastroenterological Surgery
2015
Nihon University
2004-2014
Teikyo University Hospital
2014
Shinshu University
1993-2010
Ōtani University
1996-2010
Michael E. DeBakey VA Medical Center
2010
Sclerosing pancreatitis is a unique form of that characterized by irregular narrowing the main pancreatic duct, lymphoplasmacytic inflammation pancreas, and hypergammaglobulinemia responds to glucocorticoid treatment. Preliminary studies suggested serum IgG4 concentrations are elevated in this disease but not other diseases pancreas or biliary tract.
Recent studies have demonstrated that n-3 polyunsaturated fatty acids ameliorate nonalcoholic liver disease. Although eicosapentaenoic acid (EPA), one of the major components acids, is widely used as an antilipidemic agent, its single efficacy for steatohepatitis (NASH) remains unclear. As such, we aimed to evaluate and safety EPA on 23 biopsy-proven NASH patients in a pilot trial. Highly purified (2700 mg/d) was administered 12 months assessed by biochemical parameters histology. All...
Background and Aim: The ideal method to remove small colorectal polyps is unknown. We compared removal by colon snare transection without electrocautery (cold polypectomy) with conventional polypectomy (hot in terms of procedure duration, difficulty retrieving polyps, bleeding, post-polypectomy symptoms. Methods: Patients up 8 mm diameter were randomized cold technique group) or (conventional group). principal outcome measures abdominal symptoms within 2 weeks after polypectomy. Secondary...
The mechanism of the selective conversion 1-alkynes to aldehydes by hydration was investigated isolating organic and organometallic byproducts, deuterium-labeling experiments, DFT calculations. D-labeled acetylenic hydrogen 1-alkyne found exclusively in formyl group resulting aldehydes. After reaction, presence metal-coordinated CO confirmed. All experimental results strongly suggest involvement a metal-acyl intermediate with original also bound metal center as hydride, next step being...
Recently, the need for sedation in gastrointestinal endoscopy has been increasing. However, National Health Insurance Drug Price list Japan does not include any drug specifically used sedation. Although benzodiazepines are main medication, their use cases of approved. This led Gastrointestinal Endoscopy Society to develop first set guidelines on basis evidence-based medicine collaboration with Japanese Anesthesiologists. The present comprise 14 statements, five which were judged be valid...
Background . A new agent, potassium-competitive acid blocker vonoprazan (VPZ) has potent acid-inhibitory effects and may offer advantages over conventional H. pylori eradication therapies. We aimed to compare the rate between VPZ-based treatment PPI-based one. Methods This randomized controlled trial was designed assign 141 patients with pylori- positive gastritis VPZ group (VPZ 20 mg, amoxicillin 750 clarithromycin 200 or 400 mg twice daily for 7 days) PPI (rabeprazole lansoprazole 30...
Abstract Novel complexes [(C 5 Me ) 2 Ln][B(C 6 F 4 ] (Ln = Pr, Nd, or Gd) were prepared, which in combination with i Bu 3 Al efficiently induce highly 1,4‐cis‐specific polymerization of butadiene. The activity the Gd complex/ system is high enough to exhibit good catalytic even at low temperature. Polymerization −78 °C gave polybutadiene nearly perfect 1,4‐cis microstructure (>99.9%) sharp molecular weight distribution ( M w / n 1.45) and reasonable yield. ORTEP drawing 2b . Selected...
A series of bimetallic complexes composed lanthanide metallocene and trimethylaluminum, Cp*2Ln[(μ-Me)AlMe2(μ-Me)]2LnCp*2 (Cp* = η5-C5Me5, Ln Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Tm, Yb, Lu), were prepared, the ability to catalyze polymerization butadiene in presence cocatalysts, AlR3 (R Me, iBu) [Ph3C][B(C6F5)4], was studied as a function 11 different metal species kind alkylaluminum cocatalyst. Both catalytic activity microstructure polybutadiene depended strongly on trialkylaluminum. The Gd...
OBJECTIVE: The use of propofol sedation during endoscopic procedures has increased in recent years. aim this study was to evaluate the safety and effectiveness nurse-administered low-dose for diagnostic esophagogastroduodenoscopy (EGD). METHODS: We prospectively assessed outcome complications bolus EGD. Propofol administered by injection, with a standard protocol 40 mg patients <70 years old, 30 70-89 20 90 or older. When required adequate sedation, additional doses were given, maximum 120...
Background and Goals Reliable noninvasive biomarkers to assess the histologic activity of nonalcoholic fatty liver disease (NAFLD) have not been established. As frequency Mallory bodies is known be closely associated with severity, we hypothesized that serum levels body-related proteins were correlated NAFLD evaluated this possibility. Study Serum total fragmented cytokeratin (CK) 18, heat shock protein (Hsp) 70, Hsp90α, ubiquitin+1, p38α at time biopsy measured in 118 patients their...
To examine the long term survival of geriatric patients treated with percutaneous endoscopic gastrostomy (PEG) in Japan.We retrospectively included 46 Japanese community and tertiary hospitals to investigate 931 consecutive (≥ 65 years old) swallowing difficulty newly performed PEG between Jan 1st 2005 Dec 31st 2008. We set death as an outcome explored associations among patient's characteristics at using log-rank tests Cox proportional hazard models.Nine hundred thirty one were followed up...