Junnosuke Hayasaka
A5081506802- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Diverticular Disease and Complications
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Infection Control and Ventilation
- Eosinophilic Esophagitis
- Colorectal Cancer Screening and Detection
- COVID-19 and healthcare impacts
- Neuroendocrine Tumor Research Advances
- Eosinophilic Disorders and Syndromes
- Inflammatory Bowel Disease
- Medical Device Sterilization and Disinfection
- Pancreatitis Pathology and Treatment
- Head and Neck Cancer Studies
- Colorectal Cancer Surgical Treatments
- Hematopoietic Stem Cell Transplantation
- Emergency and Acute Care Studies
- Enhanced Recovery After Surgery
- Hospital Admissions and Outcomes
Toranomon Hospital
2019-2025
University Gastroenterology
2022
Tokyo Medical and Dental University
2021-2022
American Society for Gastrointestinal Endoscopy
2022
INTRODUCTION: The bleeding source of hematochezia is unknown without performing colonoscopy. We sought to identify whether colonoscopy a risk-stratifying tool etiology and predict outcomes presenting symptoms can differentiate the etiologies in patients with hematochezia. METHODS: This multicenter retrospective cohort study conducted at 49 hospitals across Japan analyzed 10,342 admitted for outpatient-onset acute RESULTS: Patients were mostly elderly population, 29.5% had hemodynamic...
Abstract Background Direct and indirect clipping treatments are used worldwide to treat colonic diverticular bleeding (CDB), but their effectiveness has not been examined in multicenter studies with more than 100 cases. Objective We sought determine the short‐ long‐term of direct versus for CDB a nationwide cohort. Methods studied 1041 patients who underwent ( n = 360) or 681) at 49 hospitals across Japan (CODE BLUE‐J Study). Results Multivariate analysis adjusted age, sex, important...
<title>Abstract</title> Purpose Serum leucine-rich alpha-2 glycoprotein (LRG) levels are measured to monitor ulcerative colitis (UC); however, the impact of concomitant medications on LRG remains unclear. This exploratory study aimed determine effects various agents serum levels. Methods We conducted a single-center, retrospective using medical records at our hospital from October 1, 2020, June 30, 2023. Patients who underwent lower gastrointestinal endoscopy within 1 year before or after...
Introduction: Gastroesophageal reflux disease (GERD) is diagnosed based on bothersome symptoms, such as heartburn, and the presence of mucosal breaks endoscopically. Treatments that suppress gastric acid, proton pump inhibitor (PPI) vonoprazan, are frequently administered. Several studies reported regarding safety side effects long-term PPI administration, including an association with polyps. We report a case maintained symptom resolution significantly shrank polyps by performing step-down...
Currently, large, nationwide, long-term follow-up data on acute lower gastrointestinal bleeding (ALGIB) are scarce. We investigated risks of recurrence after hospital discharge for ALGIB using a large multicenter dataset.
The study aimed to identify prognostic factors for patients with acute lower gastrointestinal bleeding and develop a high-accuracy prediction tool. analysis included 8254 cases of hematochezia who were admitted urgently based on the judgment emergency physicians or gastroenterology consultants (from CODE BLUE J-study). Patients randomly assigned derivation cohort validation in 2:1 ratio using random number table. Assuming that present at time admission are involved mortality within 30 days...
Background and AimsWe aimed to determine the optimal timing of colonoscopy factors that benefit patients who undergo early for acute lower GI bleeding.MethodsWe identified 10,342 with hematochezia (CODE BLUE-J study) admitted 49 hospitals in Japan. Of these, 6270 underwent a within 120 hours were included this study. The inverse probability treatment weighting method was used adjust baseline characteristics among (≤24 hours, n = 4133), elective (24-48 1137), late (48-120 1000) colonoscopy....
Ligation therapy, including endoscopic detachable snare ligation (EDSL) and band (EBL), has emerged as an treatment for colonic diverticular bleeding (CDB); its comparative effectiveness risk of recurrent remain unclear, however. Our goal was to compare the outcomes EDSL EBL in treating CDB identify factors after therapy.We reviewed data 518 patients with who underwent (n = 77) or 441) a multicenter cohort study named Colonic Diverticular Bleeding Leaders Update Evidence From Multicenter...
Abstract Background The value of endoscopy for acute lower GI bleeding (ALGIB) remains unclear, given few large cohort studies. We aim to provide detailed clinical data ALGIB management and identify patients at risk adverse outcomes based on endoscopic diagnosis. Methods conducted a multicenter, retrospective study, named CODE BLUE J-Study, in 49 hospitals throughout Japan studied 10,342 cases admitted outpatient-onset hematochezia. Results Cases were mostly elderly, with 29.5% hemodynamic...
Background and study aims Delayed bleeding is one of the most serious adverse events gastric endoscopic submucosal dissection (ESD), especially in patients taking antithrombotic therapy. This aimed to evaluate utility safety a shielding method with autologous fibrin glue polyglycolic acid (PGA) sheets for undergoing ESD who are receiving Patients methods One hundred twenty-three were treated while therapy between December 2014 September 2017 enrolled this study. received classified into...
Objective According to consensus guidelines, eosinophilic esophagitis (EoE) is defined as a clinicopathological entity whose symptoms and histology must always be considered together. However, endoscopic findings typical of EoE are often seen in asymptomatic esophageal eosinophilia (aEE). We aimed clarify the features aEE. Methods retrospectively compared cases aEE those symptomatic EoE. Materials reviewed 146 patients who underwent upper gastrointestinal endoscopy were confirmed...
In the post-Helicobacter pylori era, autoimmune gastritis (AIG) is attracting increasing attention as an origin of gastric cancer. Here, we performed clinicopathological examination cancer complicating AIG treated in our hospital.
Superficial pharyngeal squamous cell carcinoma (PSCC) has received increasing attention as a therapeutic target in the GI field with recent innovations endoscopic submucosal dissection (ESD). However, there are currently no defined criteria for application of ESD to superficial PSCC. One problems encountered during follow-up after is cervical lymph node metastasis (LNM). Identifying clinicopathologic predictors LNM can help provide basis refinement strategies PSCC.The risk was evaluated 331...
Abstract Background and Aim While short long attachment caps are available for colonoscopy, it is unclear which type more appropriate stigmata of recent hemorrhage (SRH) identification in acute hematochezia. This study aimed to compare the performance versus hematochezia diagnoses outcomes. Methods We selected 6460 patients who underwent colonoscopy with from 10 342 cases CODE BLUE‐J study. performed propensity score matching (PSM) balance baseline characteristics between cap users. Then,...
Abstract Background and study aims Endoscopic submucosal dissection (ESD) is widely performed for superficial esophageal cancer, but stricture after extensive resection a major clinical problem. Using an ultrathin endoscope would enable endoscopists to approach lesions beyond the stricture. We evaluated feasibility of ESD. Methods To perform ESD with endoscope, we developed transparent hood knife. A total 24 ESDs were by two excised live porcine esophaguses. GIF-Q260 J Dual knife used in...
Abstract Background and study aims Infection control is essential when performing endoscopic procedures, especially during the COVID-19 pandemic. Therefore, we have developed a new shielding device called STEP for infection in upper gastrointestinal endoscopy. Patients methods consists of mask worn by patient drape that connected to covers endoscope. A suction tube attached prevents aerosols from spreading. The endoscopist operates endoscope through drape. Three endoscopists performed total...
Stigmata of recent hemorrhage (SRH) directly indicate a need for endoscopic therapy in acute lower gastrointestinal bleeding (LGIB). Colonoscopy would be prioritized patients with highly suspected SRH, but the predictors colonic SRH remain unclear. We aimed to construct predictive model efficient detection using nationwide cohort.We retrospectively analyzed 8360 admitted through hospital emergency departments LGIB CODE BLUE-J Study (49 hospitals throughout Japan). All underwent inpatient...
<b><i>Introduction:</i></b> Patients with ulcerative colitis (UC) have an increased risk of colorectal cancer. Some studies recently investigated endoscopic resection UC-associated neoplasia (UCAN), but the indications for UCAN remain controversial. This study sought to clarify problems encountered in submucosal dissection (ESD) UCAN. <b><i>Methods:</i></b> Seventeen lesions 12 patients (UCAN group) and 913 epithelial 824 control without UC...
Objective Clipping is a common technique for managing colonic diverticular bleeding (CDB), despite the lack of published evidence regarding its effectiveness. We aimed to evaluate effectiveness clipping CDB in preventing early recurrent bleeding. Methods This dual-center retrospective study included 93 patients who underwent emergency hospitalization bloody stool, diagnosed with definitive CDB, and treated or conservative treatment. The primary outcome was A logistic regression analysis...
Although almost all cases of gastric cancer are caused by Helicobacter pylori (HP) infection, there some rare exceptions. Furthermore, the clinicopathological characteristics may differ depending on HP infection status. This study aimed to determine undifferentiated-type (UD-GC) according status.The involved 83 patients with UD-GC who were selected from 1559 underwent endoscopic resection at our hospital and whose status was confirmed. Clinicopathological evaluated (eradicated, n = 28;...