A5101741447- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Diverticular Disease and Complications
- Metastasis and carcinoma case studies
- Helicobacter pylori-related gastroenterology studies
- Organometallic Complex Synthesis and Catalysis
- Renal Diseases and Glomerulopathies
- Synthetic Organic Chemistry Methods
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Screening and Detection
- Oral microbiology and periodontitis research
- Metal complexes synthesis and properties
- Vasculitis and related conditions
- Hospital Admissions and Outcomes
- Ovarian function and disorders
- FinTech, Crowdfunding, Digital Finance
- Biliary and Gastrointestinal Fistulas
- Pancreatitis Pathology and Treatment
- Electric and Hybrid Vehicle Technologies
- Epigenetics and DNA Methylation
- Colorectal and Anal Carcinomas
- Celiac Disease Research and Management
St. Marianna University School of Medicine
2015-2024
Nissan (United Kingdom)
2011-2023
Showa University Fujigaoka Hospital
2012-2022
American Society for Gastrointestinal Endoscopy
2022
Showa University
2011-2022
Weatherford College
2021
National Hospital Organization Kyushu Cancer Center
2021
Teijin (Japan)
2020
Creative Research Enterprises (United States)
2017
National Cancer Center Hospital East
2014-2017
<b>Background and study aims:</b> Compared with any other location in the gastrointestinal tract, duodenum presents most challenging site for endoscopic resection. The aim of this was to analyze clinical outcomes duodenal resection assess feasibility technique as a therapeutic procedure. <b>Patients methods:</b> A total 113 consecutive patients 121 nonampullary tumors underwent by submucosal dissection (ESD), mucosal (EMR), or polypectomy between January 2000 September 2013. Long-term were...
Background and study aim Endoscopic submucosal dissection (ESD) is known as a curative treatment for colorectal superficial neoplasms. There however need more long-term clinical data to establish the full advantages of ESD regarding very low recurrence rates. The this retrospective was determine outcomes ESD. Methods A total 423 lesions treated by adenoma/dysplasia or adenocarcinoma between 1998 2008 at single high volume referral center were included. We conducted survey on patients with...
INTRODUCTION: The bleeding source of hematochezia is unknown without performing colonoscopy. We sought to identify whether colonoscopy a risk-stratifying tool etiology and predict outcomes presenting symptoms can differentiate the etiologies in patients with hematochezia. METHODS: This multicenter retrospective cohort study conducted at 49 hospitals across Japan analyzed 10,342 admitted for outpatient-onset acute RESULTS: Patients were mostly elderly population, 29.5% had hemodynamic...
Abstract Background Direct and indirect clipping treatments are used worldwide to treat colonic diverticular bleeding (CDB), but their effectiveness has not been examined in multicenter studies with more than 100 cases. Objective We sought determine the short‐ long‐term of direct versus for CDB a nationwide cohort. Methods studied 1041 patients who underwent ( n = 360) or 681) at 49 hospitals across Japan (CODE BLUE‐J Study). Results Multivariate analysis adjusted age, sex, important...
Background The rebleeding risks and outcomes of endoscopic treatment for acute lower gastrointestinal bleeding (ALGIB) may differ depending on the location, type, etiology stigmata recent hemorrhage (SRH) but have yet to be fully investigated. We aimed identify high risk SRH propose an optimal strategy. Methods retrospectively analyzed 2699 ALGIB patients with at 49 hospitals (CODE BLUE-J Study), whom 88.6 % received treatment. Results 30-day rates untreated significantly differed among...
Although minimal invasive treatment is widely accepted in the early stages of gastric cancer (GCa), we still do not have any appropriate risk markers to detect residual neoplasia and potential for recurrence. We previously reported that aberrant DNA methylation an frequent process carcinogenesis could be useful detection neoplasia. Our goal find identify some candidate genes, using genome-wide analysis, as a marker (EGC). performed methylated CpG island amplification microarray analysis 12...
Objective We evaluated the diagnostic performance of computed tomography (CT) as an initial radiologic test for assessing optimal timing colonoscopy in patients with acute lower gastrointestinal bleeding (LGIB) and investigated effectiveness contrast-enhanced (CE) CT detecting colonic diverticular bleeding. Methods This was a retrospective study 1,604 consecutive who visited or were referred to St. Marianna University Hospital due LGIB underwent within three months after presentation between...
Currently, large, nationwide, long-term follow-up data on acute lower gastrointestinal bleeding (ALGIB) are scarce. We investigated risks of recurrence after hospital discharge for ALGIB using a large multicenter dataset.
The study aimed to identify prognostic factors for patients with acute lower gastrointestinal bleeding and develop a high-accuracy prediction tool. analysis included 8254 cases of hematochezia who were admitted urgently based on the judgment emergency physicians or gastroenterology consultants (from CODE BLUE J-study). Patients randomly assigned derivation cohort validation in 2:1 ratio using random number table. Assuming that present at time admission are involved mortality within 30 days...
Novel molybdenum- and tungsten-based catalysts induced stereospecific ring-opening metathesis polymerization (ROMP) of cycloolefins to produce a new class crystalline polymers. Various monomeric molybdenum(VI) tungsten(VI) complexes the general formula M(=O)(O−Ar)4 (M = Mo or W; (O−Ar)4 is two biphenolate four phenolate ligands) were prepared. These exhibited moderate ROMP activity in presence cocatalyst such as n-BuLi Et3Al. The molybdenum tungsten bearing substituted ligands...
Background and AimsWe aimed to determine the optimal timing of colonoscopy factors that benefit patients who undergo early for acute lower GI bleeding.MethodsWe identified 10,342 with hematochezia (CODE BLUE-J study) admitted 49 hospitals in Japan. Of these, 6270 underwent a within 120 hours were included this study. The inverse probability treatment weighting method was used adjust baseline characteristics among (≤24 hours, n = 4133), elective (24-48 1137), late (48-120 1000) colonoscopy....
A 77-year-old woman underwent an upper gastrointestinal (UGI) endoscopy screening examination, and a 10-mm reddish, submucosal tumor-like lesion was found on the posterior wall of fornix. Biopsy performed, but there no evidence malignancy, so annual follow-up by UGI decided upon. After 12 years, examination another biopsy specimen revealed adenocarcinoma fundic gland type. There had been significant change in size or shape over long period. Endoscopic dissection (ESD) en bloc resection...
Acute kidney injury (AKI) is a common complication of minimal change nephrotic syndrome (MCNS), particularly in adults. We evaluated the prevalence AKI at onset adult MCNS and analyzed influence on duration achieving complete remission (CR).A retrospective, single-centre, dynamic cohort study was conducted with biopsy-proven, first-onset, patients treated corticosteroids. Fifty-three consecutive diagnosed from January 2000 to April 2014 were enrolled. Age, gender, daily urinary protein...
Abstract Background The value of endoscopy for acute lower GI bleeding (ALGIB) remains unclear, given few large cohort studies. We aim to provide detailed clinical data ALGIB management and identify patients at risk adverse outcomes based on endoscopic diagnosis. Methods conducted a multicenter, retrospective study, named CODE BLUE J-Study, in 49 hospitals throughout Japan studied 10,342 cases admitted outpatient-onset hematochezia. Results Cases were mostly elderly, with 29.5% hemodynamic...
Abstract Imidovanadium complexes with cyclopentadienyl (Cp) ligands—(Cp)V(NC 6 H 4 Me‐4)Cl 2 (1), (Cp)V(N t Bu)Cl (2), and ( BuCp)V(N (3; BuCp = tert ‐butylcyclopentadienyl)—were synthesized through the reaction of imidovanadium trichloride (trimethylsilyl)cyclopentadiene derivatives. The molecular structure 3 was determined by X‐ray crystallography. monocyclopentadienyl complex 1 exhibited moderate activity in combination methylaluminoxane [MAO; 10.3 kg polyethylene (mol V) −1 h atm ],...
Abstract Background and Aim While short long attachment caps are available for colonoscopy, it is unclear which type more appropriate stigmata of recent hemorrhage (SRH) identification in acute hematochezia. This study aimed to compare the performance versus hematochezia diagnoses outcomes. Methods We selected 6460 patients who underwent colonoscopy with from 10 342 cases CODE BLUE‐J study. performed propensity score matching (PSM) balance baseline characteristics between cap users. Then,...