- Shape Memory Alloy Transformations
- Tissue Engineering and Regenerative Medicine
- Titanium Alloys Microstructure and Properties
- Elasticity and Material Modeling
- Fatigue and fracture mechanics
- Cardiac Structural Anomalies and Repair
- Electrospun Nanofibers in Biomedical Applications
- Metal and Thin Film Mechanics
- Advanced Welding Techniques Analysis
- Venous Thromboembolism Diagnosis and Management
- Photoacoustic and Ultrasonic Imaging
- Acute Ischemic Stroke Management
- High Entropy Alloys Studies
- Composite Material Mechanics
- Calcium Carbonate Crystallization and Inhibition
- Cerebrovascular and Carotid Artery Diseases
- Anodic Oxide Films and Nanostructures
- Aortic aneurysm repair treatments
- Orthopaedic implants and arthroplasty
- Surface Treatment and Residual Stress
- Material Properties and Applications
- Microstructure and Mechanical Properties of Steels
- Hydrogen embrittlement and corrosion behaviors in metals
Ollscoil na Gaillimhe – University of Galway
2013-2019
Background Although it is common practice to wait for an ‘embedding time’ during mechanical thrombectomy (MT) allow strut integration of a stentriever device into occluding thromboembolic clot, there scarcity evidence demonstrating the value or optimal timing wide range thrombus compositions. This work characterizes behavior clot analogs varying fibrin and cellular compositions subject indentation forces embedding times representative those imparted by MT. The purpose this study quantify...
One material that has found particular favor for use in biomedical endovascular stents is the near equi-atomic NiTi alloy, Nitinol. remarkable trait exhibited by this superelastic improvement of its fatigue performance with increasing mean strain (Ref 1, 2). Clarification into phenomenon still remains incomplete literature. This study proposes a microstructural explanation unique macroscopic behavior; it hypothesized stress-induced martensite (SIM) will stabilize which, turn, leads to...
Delivery of therapeutic-laden biomaterials to the epicardial surface heart presents a promising method treating variety diseased conditions by offering targeted, localized release with limited systemic recirculation and enhanced myocardial tissue uptake. A vast range therapeutic agents using this approach been investigated. However, fundamental factors that govern transport drug molecules from are not well understood. Here, analog biomaterial reservoir is characterized experimental...
One material that has found particular favor for use in biomedical endovascular stents is the near equi-atomic NiTi alloy, Nitinol.One remarkable trait exhibited by this superelastic improvement of its fatigue performance with increasing mean strain [1,2].Clarification into phenomenon still remains incomplete literature.This study proposes a microstructural explanation unique macroscopic behavior; it hypothesized stress-induced martensite (SIM) will stabilize which, turn, leads to observed...
For many years, computational modelling and simulation studies have been used by developers to advance device design reported in regulatory medical submissions. However, cardiovascular stent materials such models are typically assumed behave as a continuum. This approach assumes that bulk material properties apply the micro-sized structure, i.e. behavior is scale independent. size reduced, mechanical effects arise grain specimen width ratio drops below critical value. These cause deviate...
In article number 1900228 by Ellen T. Roche and co-workers, an in silico model of therapy delivery from implantable epicardial reservoir is developed with input experimental characterization to help elucidate the factors that govern drug delivery. The can be used inform future device design.