A5046689800- Cell death mechanisms and regulation
- Molecular Biology Techniques and Applications
- interferon and immune responses
- RNA and protein synthesis mechanisms
- Genomics and Phylogenetic Studies
- RNA modifications and cancer
- Glioma Diagnosis and Treatment
- Biotechnology and Related Fields
- Cancer-related Molecular Pathways
- Cancer Genomics and Diagnostics
- Water Resource Management and Quality
- Entomopathogenic Microorganisms in Pest Control
- Viral Infectious Diseases and Gene Expression in Insects
- Insect Resistance and Genetics
- Ferroptosis and cancer prognosis
Consejo Nacional de Investigaciones Científicas y Técnicas
2021-2024
Universidad Nacional de La Plata
2022-2024
Instituto de Biotecnología y Biología Molecular
2021-2024
ABSTRACT The genetic code uses three-nucleotide units to encode each amino acid in proteins. Insertions or deletions of nucleotides not divisible by three shift the reading frames, resulting significantly different protein sequences. These events are disruptive but can also create variability important for evolution. Previous studies suggest that and gene sequences evolve minimize frameshift effects, maintaining similar physicochemical properties their reference Here, we focused on tandem...
A lo largo de la historia, evaluación en universidad ha sido objeto análisis y lenta actualización, motorizada por las discusiones que se dan el seno sociedad está inserta. Se han modificado tanto los contenidos evaluados exámenes, así como instrumentos con evalúa. pesar esto, discusión sobre perfil profesional orientan diferentes formas quedado relegada. En este trabajo buscamos reflexionar impacto evaluar carrera Licenciatura Biotecnología Biología Molecular Facultad Ciencias Exactas UNLP...
Baculoviruses are insect-specific pathogens widely used in biotechnology. In particular, the Autographa californica nucleopolyhedrovirus (AcMNPV) has been exploited as a platform for bio-inputs production. This is why improvement of technologies production recombinant baculoviruses takes on particular relevance. To achieve this goal, we developed highly versatile baculoviral transfer vector generation system called PluriBAC. The PluriBAC consists three insert entry levels using Golden Gate...
ABSTRACT Purpose The aim of the present work was to investigate role Receptor-interacting protein kinase 1 (RIPK1) both in mutated and wild type isocitrate dehydrogenase (IDH) Diffuse Gliomas (DG). Patients Methods We analyzed RIPK1 mRNA expression DG databases from Cancer Genome Atlas (TCGA) containing clinical, genomic transcriptomic information 661 patients. Transcriptomic studies (mRNA levels, correlation heatmaps, survival plots Gene Ontology meta-analysis immune gene signatures) were...
PURPOSE The aim of the present work was to investigate role apoptosis inhibitor BIRC6 (baculoviral IAP repeat-containing protein 6) in breast cancer (BC), focusing particularly on its involvement metastatic cascade. METHODS We analyzed mRNA expression levels and copy number variations three BC databases from Cancer Genome Atlas comparing clinical molecular attributes. Genomic analysis performed using cBioPortal platform, whereas transcriptomic studies (mRNA levels, correlation heatmaps,...
Abstract Breast cancer is the most common as well first cause of death by in women worldwide. BIRC6 (baculoviral IAP repeat-containing protein 6) a member inhibitors apoptosis family thought to play an important role progression or chemoresistance many cancers. The aim present work was investigate inhibitor breast cancer, focusing particularly on its involvement metastatic cascade. We analyzed mRNA expression levels and Copy Number Variations (CNV) three databases from Cancer Genome Atlas...