A5083108499- Biofuel production and bioconversion
- Enzyme Production and Characterization
- Microbial Metabolic Engineering and Bioproduction
- Enzyme Catalysis and Immobilization
- Nanoparticles: synthesis and applications
- Postharvest Quality and Shelf Life Management
- GABA and Rice Research
- Microbial Metabolites in Food Biotechnology
- Microbial Metabolism and Applications
- Graphene and Nanomaterials Applications
- Food composition and properties
- Mesenchymal stem cell research
- Telomeres, Telomerase, and Senescence
- Polysaccharides and Plant Cell Walls
- Potato Plant Research
- Tissue Engineering and Regenerative Medicine
- Genomics and Rare Diseases
- Ginkgo biloba and Cashew Applications
- Phytase and its Applications
- Garlic and Onion Studies
- Phytochemicals and Antioxidant Activities
- Banana Cultivation and Research
- Medicinal Plants and Neuroprotection
- Nanoparticle-Based Drug Delivery
- Computational Drug Discovery Methods
Lahore College for Women University
2016-2025
Guilin Medical University
2024
Quaid-i-Azam University
2023
The biogenesis of silver nanoparticles by fungi is an ecologically clean and nontoxic method compared to other physical chemical methods. Thus, we aimed discuss the mycosynthesis extracellular size-controlled AgNPs. After comprehensive screening, Aspergillus fumigatus BTCB10 (KY486782) was selected for synthesis AgNPs controlled size. Characterization performed UV-Vis spectrophotometer, Zetasizer, X-Ray Diffraction (XRD), FTIR (Fourier-transform infrared), Atomic Force Microscopy (AFM),...
Biosynthesis of metal nanoparticles is an area interest among researchers because its eco-friendly approach. Current study focuses at biosynthesis silver (AgNPs) and optimization physico-chemical conditions to obtain mono-dispersed stable AgNPs having antimicrobial activity. Initially Bacillus mojavensis BTCB15 produced 105 nm. Silver were characterized by particle size analyzer, UV-Vis Spectroscopy, Fourier transforms infrared spectroscopy (FTIR), Atomic force microscopy (AFM), X-ray...
Cellulases involved in the hydrolysis of cellulose and plays a vital role different industries like textile, detergent paper Feed industry. have been prospective target for research by both academic industrial sectors because intricacy enzyme system enormous potential. In present work Thermomyces dupontii, which had previously isolated recorded as promising cellulase producer were used. Both endoglucanases betaglucosidases purified to its homogeneity ammonium sulfate followed anion exchange...
The new concept of functional foods has led to the varieties in production that provide not only basic nutrition, but can also warrant good health and longevity. This study deals with evaluation fortified yogurts' Cinnamomum verum, Elettaria cardamomum, Beta vulgaris Brassica oleracea. qualitative quantitative phytochemical analysis above mentioned plant extracts before using them into preparation yoghurt was carried out. sensory enriched yogurts out 9 point hedonic scale. Comparative...
In this study, thermophilic pectinase-producing strains were isolated. Among all the isolates, strain No. 4 was identified as Aspergillus fumigatus BT-4 based on its morphology and 18 S rDNA analysis. This employed to screen various fermentation media enhance pectinase production. Pectinases are crucial enzymes with significant industrial applications, particularly in food textile industries. Identifying efficient producers optimizing their production processes essential for improving...
In the current study assessment of antimicrobial and phytochemical properties
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is one of the key targets for atherosclerosis drug development as its binding with low-density lipoprotein receptor leads to atherosclerosis. The protein-ligand interaction helps understand actual mechanism pharmacological action. This research aims discover best inhibitory candidates targeting PCSK9. To start with, reported ACE inhibitors were incorporated into pharmacophore designing using PharmaGist produce models. Selected models...
Different fungal strains were isolated from the local soil, fruits and vegetables on basis of pectin hydrolysis. All identified through microscopic studies screened for pectinase production using solid state fermentation. The strain as Aspergillus niger IBT-7 showed highest production. selected was further subjected to optimization different physical nutritional parameters enhance pectinase. Amongst seven media tested M1 containing rice bran, moistened with Czapek’s nutrient medium During...
The present study deals with the isolation screening and optimization of fungal strain for pectinase production.The strains were isolated from different sources, including soil, fruits etc. Qualitative was performed on basis pectin hydrolysis zone.While, quantitative carried out employing submerged fermentation.Among all showing highest pectinolytic potential selected identified assigned code Aspergillus niger ABT-5.The influence fermentation media production evaluated.The M5 medium...
Zinc oxide nanoparticles ZnO NPs due to their unique properties have diverse applications in different fields of life. Bacterial synthesis is an eco-friendly, simple and inexpensive way. In this study, among eighteen bacterial isolates, eight confirmed synthesis. On the basis sharp absorption peak at 354 nm, growth conditions for gram positive Bacillus cereus H-SC1 were further optimized. Under optimum parameters such as incubation temperature 37ºC, pH 9, inorganic salt (NH2)2SO4, SDS...
Telomerase deficiency has been associated with inadequate differentiation of mesenchymal stem cells. However, the effect telomerase on differential regulation osteoblast specific genes, based functional gene grouping, during in vitro not reported before. To examine these effects, Terc -/- BMSCs (bone marrow stromal cells) were employed which exhibited reduced proliferation osteogenesis along increased population doubling time and level compared to wild type (WT) normal culture. Osteogenic...
At present, cellulases are the most important enzymes worldwide, and their demand has been increasing in industrial sector owing to notable hydrolysis capability. In present study, contrary conventional techniques, three physical parameters were statistically optimized for production of cellulase by thermophilic fungi using response surface methodology (RSM). Among all tested strains, best producing fungus was identified as Talaromyces thermophilus – both morphologically molecularly through...
With the surprising development across cosmetic and personal care companies re-utilization of tools is a common practice. Isolation detection human skin pathogens from 100 samples beauty salon i.e., blusher brush, face sponge wax has been done. All were examined microbiologically for contamination Staphylococcus aureus, Pseudomonas aeruginosa, yeast fungus. It was observed that percentage aureus higher (100% in sponge, 100% 88% wax) than aeruginosa (69.6% 81.8% brush 73.5% wax), where counts...
Background: The prevalence of the chronic metabolic disorder Type 2 diabetes mellitus (T2DM) is increasing steadily, and has even turned into an epidemic in some countries. T2DM results from defective responses to insulin obesity a major factor behind resistance T2DM. Insulin receptor substrate (IRS) proteins are adaptor signalling pathway. controlled through tyrosine phosphorylation IRS-1 IRS-2, dysregulation IRS may lead glucose intolerance eventually resistance. Objective: In this work,...