A5090593197- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Phytochemicals and Antioxidant Activities
- Postharvest Quality and Shelf Life Management
- Biofuel production and bioconversion
- Enzyme Production and Characterization
- Plant Physiology and Cultivation Studies
- Hepatitis Viruses Studies and Epidemiology
- GABA and Rice Research
- Radiation Effects and Dosimetry
- Cytokine Signaling Pathways and Interactions
- Food Science and Nutritional Studies
- Research in Cotton Cultivation
- Nanocomposite Films for Food Packaging
- Animal Nutrition and Physiology
- Graphene and Nanomaterials Applications
- Ethnobotanical and Medicinal Plants Studies
- Advanced Cellulose Research Studies
- Studies on Chitinases and Chitosanases
- Skin Protection and Aging
- Moringa oleifera research and applications
- Pregnancy and preeclampsia studies
- Dyeing and Modifying Textile Fibers
- Microbial Metabolic Engineering and Bioproduction
Lahore College for Women University
2016-2024
Bihar Agricultural University
2017-2022
Centre of Excellence in Molecular Biology
2009-2014
University of the Punjab
2009-2012
Tokyo Medical and Dental University
2009
Chinese University of Hong Kong
2009
Government of Pakistan
2009
Since the first reported outbreak of dengue hemorrhagic fever in Pakistan, several mini outbreaks have erupted region. Dengue virus serotype 3 (DEN-3) was documented 2005 Karachi. Reports show that is prevalent Lahore since 2008. Serotype 2 (DEN-2) major circulating Pakistan as it 1994. We conducted a detailed study three infection occurred years 2007, 2008 and 2009 by using molecular techniques such PCR nucleotide sequencing C-prM gene junction virus.Through analysis 114 serum samples...
AIM:To assess the association between chronic hepatitis C virus (HCV) infection and hepatocellular carcinoma (HCC) in Pakistan, genotype distribution among these HCC patients. METHODS:One hundred sixty-one subjects with were included this study.Liver biopsy was performed on 145 of patients; sixteen excluded because they failed to fulfill inclusion criteria.Qualitative polymerase chain reaction (PCR) for B HCV.Samples positive HCV RNA genotyped using genotypespecific PCR confirmed by 5'...
Cellulases involved in the hydrolysis of cellulose and plays a vital role different industries like textile, detergent paper Feed industry. have been prospective target for research by both academic industrial sectors because intricacy enzyme system enormous potential. In present work Thermomyces dupontii, which had previously isolated recorded as promising cellulase producer were used. Both endoglucanases betaglucosidases purified to its homogeneity ammonium sulfate followed anion exchange...
The new concept of functional foods has led to the varieties in production that provide not only basic nutrition, but can also warrant good health and longevity. This study deals with evaluation fortified yogurts' Cinnamomum verum, Elettaria cardamomum, Beta vulgaris Brassica oleracea. qualitative quantitative phytochemical analysis above mentioned plant extracts before using them into preparation yoghurt was carried out. sensory enriched yogurts out 9 point hedonic scale. Comparative...
In the current study assessment of antimicrobial and phytochemical properties
Postharvest litchi fruit is highly perishable and vulnerable to pericarp browning (PB), which affects marketability. In this study, the effect of vacuum infiltrated methyl jasmonate (0, 1, or 2 mM) on quality fresh cold stored (7 ± 1 °C RH 85–90%) litchi. The MeJA effectively reduced PB increased storage life up 16 d by retaining higher weight, soluble solids, acidity, anthocyanin contents. (2 treated fruits maintained levels phenols, ascorbic acid antioxidant activity. Moreover,...
ABSTRACT Hydrogen sulphide (H 2 S) has emerged as a gasotransmitter molecule that modulates several physiological functions in plants, specially, different biotic and abiotic stresses. Pointed gourd (PG) fruits start losing their soft texture appealing colour within 2–3 days of harvest, resulting poor marketability shelf life. Here, the effect exogenous H S (1 m ) application on lignification other biochemical markers linked to ripening, shelf‐life edible quality PG was assessed during cold...
Cancer is a leading concern and important cause of death worldwide. non-communicable illness defined as uncontrolled division cells. It can develop into metastatic cancer when tumor cells migrate to other organs. In recent years evidence has emerged that the bioavailability Asn play crucial role in metastasis. non-essential amino acid formed from an ATP dependent catalyzed reaction by enzyme asparagine synthetase (ASNS), where Asp Gln are converted Glu, respectively. The human ASNS consist...
At present, cellulases are the most important enzymes worldwide, and their demand has been increasing in industrial sector owing to notable hydrolysis capability. In present study, contrary conventional techniques, three physical parameters were statistically optimized for production of cellulase by thermophilic fungi using response surface methodology (RSM). Among all tested strains, best producing fungus was identified as Talaromyces thermophilus – both morphologically molecularly through...
The term 'herbal tea' refers to a beverage made from the medicinal plants, herbs and spices. Herbal teas are non-caffeinated consumed worldwide due their therapeutic healing properties. present study aimed at development of herbal tea formulation using Cymbopogon citratus leaves, Foeniculum vulgare seeds Murraya koenigii leaves its qualitative quantitative evaluation. Sensory evaluation was carried out 9point headonic Scale. Qualitative phytochemical analysis, antioxidant activity DPPH assay...
Hepatitis C is a major health problem affecting more than 200 million individuals in the world. Current treatment regimen consisting of interferon alpha and ribavirin does not always succeed eliminating virus completely from patient's body. One mechanisms by which evades antiviral effect involves protein kinase (PKR) eukaryotic initiation factor 2 (eIF2a) phosphorylation homology domain (PePHD). This genotype 1 strains reportedly homologous to PKR its target eIF2a. By binding PKR, PePHD...
HCV infection is strongly associated with development of insulin resistance and type-2 diabetes, however molecular mechanism these associations not known. The aim this review was to conduct a comprehensive literature search understand the nature association between hepatitis C virus (HCV) (IR). We also explored role core protein NS5a in modulating course insulin-signaling pathway.We searched Directory Open Access Journals (DOAJ) Google Scholar, Pubmed (NLM), LISTA (EBSCO), Web Science (TS...
Hepatitis delta virus (HDV) is a highly pathogenic and causes rapid disease progression from fulminant hepatitis to development of hepatocellular carcinoma in patients infected with B (HBV). HDV endemic Pakistan; however, there are no available data on prevalence among the high-risk group HBV-infected pregnant women. A total 1,394 women, visiting different public-sector hospitals Lahore, were enrolled this study. Their demographic blood samples collected May 2016 July 2017. Samples screened...
The variability within the hepatitis C virus (HCV) genome has formed basis for several genotyping methods and used widely HCV worldwide. aim of present study was to determine percent nucleotide identity in isolates prevalent different geographical regions Pakistan. Sequencing analysis 5'noncoding region (5'-NCR) 100 RNA-positive patients representing all four provinces Pakistan were carried out using ABI PRISM 3100 Genetic Analyzer. results showed that type 3 is predominant genotypes...
Sodium hydrosulfite is conventionally used for the color stripping of reactive dyes in textile industry. However, research has been focused on eco-friendly processes to reduce wastewater generation recent years. This study aimed at estimating efficacy ozone according dyes’ chromophore groups. The dyed cotton-knitted fabric with three that have phthalocyanine (Reactive blue 21), diazo black 5) and monoazo yellow 84) chromophores was treated ozone. effect experimental parameters (pH, dose...
CLCuV is one of the most serious causes cotton damage for which no adequate remedy available. The possible solution to this problem may be transfer resistant genes into background agronomical CLCuV-tolerant varieties. In response viral infection, several plants show qualitative and quantitative variations in gene expression. To study expression between diseased tolerant plants, DDRT-PCR was performed. Upregulated observed among cDNA transcripts screened through random primers. Seven have...