A5073097018- Phytase and its Applications
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Folate and B Vitamins Research
- Soil and Unsaturated Flow
- Oral and gingival health research
- Hippo pathway signaling and YAP/TAZ
- Mobile Agent-Based Network Management
- Metabolism and Genetic Disorders
- Customer Service Quality and Loyalty
- Autophagy in Disease and Therapy
- Advancements in PLL and VCO Technologies
- Lipid metabolism and biosynthesis
- Ubiquitin and proteasome pathways
- Digital Marketing and Social Media
- Geotechnical Engineering and Soil Mechanics
- Peer-to-Peer Network Technologies
- RNA Interference and Gene Delivery
- Access Control and Trust
- Electrostatic Discharge in Electronics
- Wnt/β-catenin signaling in development and cancer
- Clay minerals and soil interactions
- Consumer Behavior in Brand Consumption and Identification
- Trace Elements in Health
- VLSI and Analog Circuit Testing
- Parathyroid Disorders and Treatments
University of California, Irvine
2023-2024
Konkuk University
2019-2023
Samsung (South Korea)
2022
Abstract The Hippo pathway is commonly altered in cancer initiation and progression; however, exactly how this becomes dysregulated to promote human development remains unclear. Here we analyze the somatic mutations genome functionally annotate their roles targeting pathway. We identify a total of 85 loss-of-function (LOF) missense for genes elucidate underlying mechanisms. Interestingly, reveal zinc-finger domain as an integral structure MOB1 function, whose LOF head neck tumor growth....
This study was conducted to determine catalytic properties of wheat phytase with exopolyphosphatase activity toward medium-chain and long-chain inorganic polyphosphate (polyP) substrates for comparative purpose.Exopolyphosphatase assay polyP75 (medium-chain polyP average 75 phosphate residues) polyP1150 (long-chain 1150 performed at pH 5.2 7.5. Its these investigated in the presence Mg2+, Ni+2, Co2+, Mn2+, or EDTA. Michaelis constant (Km) maximum reaction velocity (Vmax) were determined from...
Objective: This experiment was conducted to find out the immunological effects of wheat phytase when long-chain inorganic polyphosphate (polyP) treated with added a macrophage cell line, Raw 264.7, compared intact polyP.Methods: Nitric oxide (NO) production 264.7 cells exposed P700, polyP an average 1,150 phosphate residues, or without phytase, measured by Griess method. Phagocytosis assay P700 in investigated using neutral red uptake. The secretion tumor necrosis factor α (TNF-α)...
The objective of this study was to characterize the enzymatic hydrolysis lipopolysaccharide (LPS) by wheat phytase and investigate effects phytase-treated LPS on in vitro toxicity, cell viability release a pro-inflammatory cytokine, interleukin (IL)-8 target cells compared with intact LPS. phosphatase activity towards investigated presence or absence inhibitors such as L-phenylalanine L-homoarginine. In toxicity hydrolyzed comparison assessed. Cell human aortic endothelial (HAE) exposed...
Objective: This study was performed to investigate the potential effect of wheat phytase on long-chain inorganic polyphosphate (polyP)-mediated interleukin 8 (IL-8) signaling in an intestinal epithelial cell line, HT-29 cells.Methods: Cell viability and release pro-inflammatory cytokine IL-8 cells exposed polyP1150 (average 1,150 phosphate residues) treated with or without were measured by EZ-CYTOX kit ELISA kit, respectively. Also, activation cellular inflammatory factors NF-κB MAPK (p38...
The aim of this study was to investigate the protective effect wheat phytase as a structural decomposer inflammatory nucleotides, extracellular adenosine triphosphate (ATP), and uridine diphosphate (UDP) on HT-29 cells.Phosphatase activities against ATP UDP investigated in presence or absence inhibitors such L-phenylalanine L-homoarginine using Pi Color Lock gold phosphate detection kit. Viability cells exposed intact- dephosphorylated-nucleotides analyzed with an EZ-CYTOX Secretion levels...
As autonomous driving becomes commercialized, the requirements for safe and advanced integrated circuits automotive applications have become stricter than at any other time. IS026262 (Road Vehicle Functional Safety Standard) determines risk level associated with systematic random failures defines of reduction required to achieve safety levels target by integrity (ASIL). has a metric system's ability detect failures, diagnostic coverage (DC) requirement ASIL is 90 <sup...
In this study, we performed one dimensional cylindrical sedimentation tests to investigate the impact of clay mineralogy, ionic concentration, valence on sedimentation, and self-consolidation behavior clay. The result at 1,000% 2,000% water content indicates that = showed higher coefficient initial settling velocity, faster initiation termination self-consolidation. Additionally, velocity decreased as concentration (0.01 - 2 M) increased, kaolinite than illite. observed experimental results...