A5101911704- Acute Ischemic Stroke Management
- Neurological Disorders and Treatments
- Nutrition and Health in Aging
- Stroke Rehabilitation and Recovery
- Antibiotic Resistance in Bacteria
- Stress Responses and Cortisol
- Dementia and Cognitive Impairment Research
- Vitamin D Research Studies
- Dysphagia Assessment and Management
- Animal Nutrition and Physiology
- Berberine and alkaloids research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Vitamin C and Antioxidants Research
- Clostridium difficile and Clostridium perfringens research
- Magnesium in Health and Disease
- Insect Pest Control Strategies
- Neurological Disease Mechanisms and Treatments
- LGBTQ Health, Identity, and Policy
- Intracerebral and Subarachnoid Hemorrhage Research
- Anesthesia and Neurotoxicity Research
- Cancer Mechanisms and Therapy
- Agriculture, Soil, Plant Science
- Lymphoma Diagnosis and Treatment
- Antibiotics Pharmacokinetics and Efficacy
Wenzhou Medical University
2016-2024
First Affiliated Hospital of Wenzhou Medical University
2016-2024
Wuhan University
2022
Soochow University
2018
Second Affiliated Hospital of Soochow University
2018
Ruian People's Hospital
2016
Iowa State University
1982-1983
Low levels of serum vitamin D are common in patients with mood disorders and stroke. It has been shown that low indicate a risk depression post-stroke subjects. Our aim was to determine the relationship between anxiety (PSA). A consecutive series 226 first acute ischemic stroke were recruited followed up for 1 month. Serum measured within 24 hours admission. Patients significant clinical symptoms Hamilton scale score >7 diagnosed as having PSA. In addition, 100 healthy subjects controls...
Whether leukoaraiosis burden retards short-term recovery after minor stroke is unclear. We investigated the association between and early of neurological function a first ischemic in 217 acute patients (National Institutes Health Stroke Scale (NIHSS) score ≤5). Leukoaraiosis severity was graded according to Fazekas scale categorized into none mild (0–2; n = 143) or severe (3–6; 74) groups. NIHSS Minimum Mental State Examination (MMSE) were assessed at baseline 30 days. Univariate analysis...
Purpose: To explore the predictive value of nutritional risk for all-cause death and functional outcomes among elderly acute stroke patients.Patients Methods: A total 479 patients were enrolled in this study.The was screened by GNRI NRS-2002.The primary outcome death, secondary poor prognosis defined as a modified Rankin Scale (mRS) score ≥3.Results: Based on NRS-2002, with had higher at 3 months (adjusted OR: 3.642, 95% CI 1.046~12.689)and years 2.266, 1.259~4.076)and adverse 2.748,...
Abstract Background Stroke is a leading cause of death and functional impairment in older people. To assess the prospective association between fasting blood glucose-to-glycated hemoglobin ratio all-cause mortality poor prognosis stroke patients. Methods A total 971 Chinese inpatients with acute (mean age 65.7) were consecutively enrolled clinical study followed up for 12 months after discharge. Stress hyperglycemia was measured using glucose (FBG, mmol/L)/glycated (HbA1c, %). The primary...
Background and Purpose . The aim of this study was to explore the role DL-3-n-butylphthalide (NBP) in cerebral ischemia-reperfusion injury (CIRI) mice model. involvement extracellular signal-regulated kinase (ERK) signaling pathway also investigated. Methods All were divided into five groups: sham-operated group, CIRI NBP pretreatment treatment + group. model established by use Pulsinelli four-vessel occlusion method. Pretreatment received (90 mg/kg/d) three times a day within four days...
Post-stroke depression (PSD) is a common psychiatric complication of stroke that associated with poor outcome in patients. Our aim was to assess the association between serum magnesium levels and presence PSD Chinese Two hundred nine patients were included study. Depressive symptoms measured by 17-Hamilton Rating Scale for Depression at 3 months after stroke. Based on depressive symptoms, diagnoses made line DSM-IV criteria PSD. Serum evaluated using dimethyl aniline blue colorimetric method...
SUMMARY Intraluminal perfusion with Escherichia coli heat-stable enterotoxin ( st ) reversed water and electrolyte movements from net absorption to secretion in porcine jejunal segments. Addition of berberine hydrochloride (3.2 × 10 −5 M the perfusate reduced secretory response water, sodium, potassium, chloride enhanced control At lower concentrations (1.1 ), -exposed segments, but only decrease sodium flux was significant. In presence berberine, mucosal enzyme activities adenosine...
Intraluminal perfusion of pig jejunum with Escherichia coli heat-stable enterotoxin reversed net absorption water and electrolytes to secretion. Addition atropine (2 x 10(-5)M) the perfusate reduced secretory response enhanced sodium chloride in control segments. Indomethacin (1.4 10(-3)M), acetazolamide (2.2 or ethacrynate (3.1 10(-4)M) had no effect. Mucosal disaccharidase activity Na-K-ATPase were not altered by enterotoxin. The results suggest that blockade cholinergically mediated...
Poor sleep quality and vitamin D deficiency are common in stroke patients. Our aim was to evaluate the possible association between acute ischemic (AIS) A total of 301 AIS patients were screened completed 1-month follow-up. Serum 25-hydroxyvitamin [25(OH)D] used assess status by a competitive protein-binding assay at baseline. All divided into equal quartile according distribution 25(OH)D. One month after stroke, evaluated using Pittsburgh Sleep Quality Index (PSQI) Epworth Sleepiness Scale...
Endothelial dysfunction (ED) is associated with the progression of sepsis. Ruscogenin (RUS) has shown considerable efficacy in treating ED and In current study, effects RUS on sepsis-induced were assessed, mechanism was explored by focusing interactions miRs.Sepsis induced mice human umbilical vein endothelial cells (HUVECs) using LPS method. Expression profile miRs responding to sepsis determined. Symptoms examined after treatment RUS. Changes mouse survival, arterial structure, systemic...
Post-stroke anxiety (PSA) is serious psychosomatic comorbidity among patients with stroke, but whether obesity could be positively associated PSA currently unknown. The purpose of this study was to investigate the potential association between and subsequent risk in stroke. A total 441 acute ischemic stroke (AIS) onset were consecutively recruited within 7 days, post-stroke depression (PSD) evaluated by using a 14-item Hamilton scale (HAMA) 17-item (HAMD) at end 1-month follow-up. odds ratio...
Objective: To investigate the associations between adverse childhood experiences (ACE) and substance use behaviors among lesbians to provide a scientific basis for high-risk population identification formulation of targeted intervention measures. Methods: Lesbians who participated in routine AIDS voluntary counseling, testing services, activities, peer recommendations were recruited from July December 2018, with help LesPark Beijing. Convenient sampling method was used. Demographic...
Controlling Nutritional Status (CONUT) Score is useful for the nutritional screening. We aimed to explore whether CONUT score may predict a 3-month functional outcome in hemorrhagic stroke (AHS). Totally, 349 patients with incident AHS were consecutively recruited, and their malnutrition risks determined using high of ≥ 2. Poor outcomes defined as modified Rankin Scale (mRS) 3 at months. A total 328 (mean age, 60.4 ± 12.83 years; 66.8% male) included, 172 (52.40%) risk 104...
Abstract Background Stroke is a leading cause of death and functional impairment in order people. To assess the prospective association between fasting blood glucose-to-glycated hemoglobin ratio all-cause mortality poor prognosis stroke patients. Methods A total 941 Chinese inpatients with acute (mean age 65.7) were consecutively enrolled clinical study followed up for 12 months after discharge. Stress hyperglycemia was measured using glucose (FBG, mmol/L)/glycated (HbA1c, %). The primary...