- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Ergonomics and Musculoskeletal Disorders
- Musculoskeletal pain and rehabilitation
- Hematopoietic Stem Cell Transplantation
- Workplace Health and Well-being
- Suicide and Self-Harm Studies
- Carcinogens and Genotoxicity Assessment
- CNS Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Viral-associated cancers and disorders
- Multiple Myeloma Research and Treatments
- Diabetes Management and Research
- Diabetes Treatment and Management
- Occupational and environmental lung diseases
- Bone health and osteoporosis research
- Hematological disorders and diagnostics
- Smoking Behavior and Cessation
- Urinary Bladder and Prostate Research
- Occupational exposure and asthma
- Vitamin K Research Studies
- T-cell and Retrovirus Studies
- Neutropenia and Cancer Infections
- Pressure Ulcer Prevention and Management
Kumamoto University
2023
Edogawa Hospital
2023
Kobe City Medical Center General Hospital
2011-2020
Kobe Medical Center
2020
Kyoto University
2019
Ono Clinic
2009-2015
Fujita Health University
2003-2015
Tokyo Metropolitan Government
2012
Tokyo Medical Examiner's Office
2012
Mie University
2011-2012
The efficacy and safety of insulin degludec (IDeg) was compared with detemir (IDet), both administered once daily (OD) as basal treatment in participants type 1 diabetes mellitus (T1DM). primary outcome non-inferiority IDeg to IDet glycated haemoglobin (HbA1c) reduction after 26 weeks.
The long‐term safety and tolerability of insulin degludec ( IDeg ) was compared with that detemir IDet ), as basal treatment in participants type 1 diabetes mellitus T1DM ). In the present multinational, 26‐week core + extension, controlled, open‐label, parallel‐group trial, adults were randomized to or combined meal‐time bolus aspart. administered once daily, whilst twice daily depending on patients' glycaemic control. After year, provided a 33% lower rate nocturnal hypoglycaemia :...
We examined the influence of work-related effort–reward imbalance and overcommitment to work (OC), as derived from Siegrist's Effort–Reward Imbalance (ERI) model, on hypothalamic–pituitary–adrenocortical (HPA) axis. hypothesized that, among healthy workers, both cortisol dehydroepiandrosterone (DHEA) secretion would be increased by OC and, a result, cortisol-to-DHEA ratio (C/D ratio) not differ or OC. The subjects were 115 female nursery school teachers. Salivary cortisol, DHEA C/D used...
A cross-sectional questionnaire study was carried out on nursery school (NS) teachers in public schools N city Japan to determine the magnitude of associations probable risk factors with neck, shoulder, and arm pain, adjusting for potential confounders logistic regression models. Of 1438 subjects, responded questionnaire, 959 NS charge a separate or mixed group children were subjected analyses. Prevalence neck and/or shoulder pain 33.6%-35.4% aged 0, 0-1, 4, 5 contrast 25.0-29.8% those 1,2,...
A prospective cohort study was conducted to examine the effects of psychosocial job characteristics on smoking cessation. Previous studies have failed indicate consistently that predicted Using Demand-Control-Support (DCS) and Effort-Reward Imbalance (ERI) models simultaneously, we assessed more comprehensively than did previous researchers. This performed using a population derived from corporate manufacturing group in Japan. At baseline, 579 (41%) 1,423 middle-aged (≥39 years) male...
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with poor prognosis. We encountered unique case of BPDCN that was leukemic at presentation without skin lesion and expressed CD33 antigen. A 74-year-old man admitted because dyspnea. Physically, hepatosplenomegaly, but not lesions superficial lymph node swelling, noted. The white blood count 33.6 × 10(9)/L 19% giant abnormal cells. These cells were positive for CD4, CD86, CD123 (bright), BDCA-2, HLA-DR,...
Crystallization that proceeds above the glass transition temperature upon heating glassy or amorphous state is referred to as "cold crystallization", which has often been observed in supercooled phases of molecular materials followed by thermodynamically stable crystalline phase. Although this behavior common for macromolecules with high structural flexibility among segments preserving wide range corresponding phases, cold crystallization small molecules relatively rare and there still less...
A cross-sectional questionnaire study was conducted on cooks working for nursery schools in N city order to verify epidemiological evidence of the work-relatedness low back pain among them. After female workers aged 30 or more were selected from a base 2,799 social welfare facilities, prevalence (n = 240) compared with school teachers 955). Age-standardized ratios (PRs) 1.9 (95% CI: 1.5-2.5) teachers. Among cooks, relative risks increased increase number lunches be prepared and decreased...
Abstract The association between asbestos fibers in human lung tissues and those other extrapulmonary organs was studied by analysing three autopsied cases, one of whom had a high pulmonary burden, an intermediate low burden. amount, types sizes the lung, liver, spleen, pancreas, kidney, gastrointestinal tract were identified measured transmission electron microscopy equipped with energy dispersive X‐ray analyser. following results obtained: 1) concentrations tended to increase that tissues....
The relation between economically stressful factors and musculoskeletal disorders was investigated by comparing two school lunch service centres (A B). Action Limit advocated NIOSH used to evaluate the manual lifting tasks. workers in centre A had a significantly higher prevalence of complaints, more clinical findings greater medical treatment experience than those B. ratio actual load also larger ergonomic advantages B, which resulted markedly decreased repetitive use arms hands,...
Reliability and validity of the Japanese-translated version Swedish Demand-Control-Support Questionnaire (J-DCSQ) was examined. The subjects comprised 212 women working in nursery schools. 17-item J-DCSQ consists three subscales: psychological demands (PD), decision latitude (DL), social support (SS). With regard to reliability, one-week test-retest reliability internal consistency were proved at a sufficient level. Weighted kappa coefficients near or greater than 0.60 for all items....
The present study aimed to validate screening tools that could be used identify depression among workers.Diagnostic test study.Workers from three Japanese companies agreed participate.Recruitment for the group 1 occurred between January 2001 and February 2004, 89 participants (81 men 8 women with a mean age of 38.4±6.6 years) (98.8%) took part in study. Recruitment 2 July 2000 1500 (1408 92 40.9±7.2 (94.2%) Demographic data are shown supplementary table 1.the Beck Depression Inventory (BDI)...
The dose dependent effects of chronic exposure to toluene on the neuronal marker proteins (gamma-enolase, calbindin-D28k) and glial cell (alpha-enolase, creatine kinase-B, beta-S100 protein) were investigated in central nervous system (CNS) rats. Three groups animals exposed 100 ppm, 300 or 1000 ppm vapour eight hours a day, six days week for 16 weeks. contents substances determined with enzyme immunoassays. A significant increase three was noted cerebellum after toluene; more pronounced...
A "tooth impression" was devised to measure head vibration. The vertical vibration of four subjects measured with the tooth impression during exposure hand sinusoidal at acceleration levels 3.15, 10.0, and 31.5 m/s2 root mean square in range 8-200 Hz. While a standing position, pulled vibrating handle upward force 5 kg elbow joint stretched tests. measurement repeated twice. difference between two measurements within 3 dB, level which suggests that this method has good reproducibility....