Wenru Li

ORCID: 0000-0002-2386-5563
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About
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Research Areas
  • Bacterial biofilms and quorum sensing
  • Insect-Plant Interactions and Control
  • Antibiotic Resistance in Bacteria
  • Insect Resistance and Genetics
  • Insect and Pesticide Research
  • Essential Oils and Antimicrobial Activity
  • Nanoparticles: synthesis and applications
  • Insect Pest Control Strategies
  • Graphene and Nanomaterials Applications
  • Advancements in Battery Materials
  • Advanced battery technologies research
  • Advanced Battery Materials and Technologies
  • Ferroelectric and Piezoelectric Materials
  • Multiferroics and related materials
  • Garlic and Onion Studies
  • Fungal Plant Pathogen Control
  • Problem and Project Based Learning
  • Advanced Nanomaterials in Catalysis
  • Plant Pathogenic Bacteria Studies
  • Edible Oils Quality and Analysis
  • Biosensors and Analytical Detection
  • Microwave Dielectric Ceramics Synthesis
  • Neurobiology and Insect Physiology Research
  • Innovative Teaching Methods
  • Pharmaceutical and Antibiotic Environmental Impacts

Second Xiangya Hospital of Central South University
2023-2025

Central South University
2023-2025

Qingdao Institute of Bioenergy and Bioprocess Technology
2024

Northwest Institute of Mechanical and Electrical Engineering
2024

Northwest A&F University
2024

Shandong University
2024

Institute of Microbiology
2009-2023

Guangdong Academy of Sciences
2014-2023

Ningbo University
2020-2022

Fujian Agriculture and Forestry University
2017-2021

Abstract The antifungal activity, kinetics and molecular mechanism of action garlic oil against Candida albicans were investigated in this study using multiple methods. Using the poisoned food technique, we determined that minimum inhibitory concentration was 0.35 μg/mL. Observation by transmission electron microscopy indicated could penetrate cellular membrane C. as well membranes organelles such mitochondria, resulting organelle destruction ultimately cell death. RNA sequencing analysis...

10.1038/srep22805 article EN cc-by Scientific Reports 2016-03-07

Litsea cubeba oil is extracted from the fresh fruits of by distillation. In this study, its chemical constituents, antibacterial activity, kinetics and effects against Escherichia coli were studied. Its minimum inhibitory concentration (MIC) bactericidal (MBC) both 0.125% (v/v) toxic food method. Moreover, kinetic curves indicated 0.0625% litsea was able to prolong growth lag phase E. cells approximate 12 hours while kill completely. Furthermore, transmission electron microscope (TEM)...

10.1371/journal.pone.0110983 article EN cc-by PLoS ONE 2014-11-05

Tolerance to chemical insecticides can be driven by the necessity of herbivorous insects defend against host plant-produced phytochemicals. However, how phytochemicals are sensed and further transduced into a defense response associated with insecticide tolerance is poorly understood. Herein, we show that pre-exposure flavone, flavonoid phytochemical, effectively enhanced larval multiple synthetic elevated detoxification enzyme activities in Spodoptera litura. RNA-Seq analysis revealed...

10.1021/acs.jafc.1c02695 article EN Journal of Agricultural and Food Chemistry 2021-06-25

Background: Given the limitations of traditional pharmacology pedagogical method, diverse novel teaching methods have been widely explored. In this study, we performed a network meta-analysis (NMA) to evaluate effects different strategies in education. Methods: Literature databases were searched from their inception November 2022, and studies screened according predefined inclusion exclusion criteria extract important information. Outcomes, including theoretical test scores, experimental...

10.3389/fphar.2023.1145456 article EN cc-by Frontiers in Pharmacology 2023-03-15

Adaptation to phytochemicals in herbivorous insects can influence tolerance insecticides. However, it is unclear how use as cues activate their metabolic detoxification systems. In this study, we found that dietary exposure xanthotoxin enhanced of Spodoptera litura larvae λ-cyhalothrin. Xanthotoxin ingestion significantly elevated the mRNA levels 35 genes well transcription factors Cap 'n' collar isoform-C (CncC) and its binding factor small muscle aponeurosis fibromatosis isoform-K (MafK)....

10.1021/acs.jafc.1c04519 article EN Journal of Agricultural and Food Chemistry 2021-11-08

Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen that can cause severe respiratory tract infections. Geraniol, chemical component of essential oils, has antimicrobial and anti-inflammatory activities, along with low toxicity. However, the effect mechanism geraniol against P. virulence factors are rarely studied. In this study, we investigated quorum sensing (QS) inhibitory effects mechanisms PAO1, using physiological biochemical techniques, quantitative reverse transcription...

10.3389/fmicb.2023.1190619 article EN cc-by Frontiers in Microbiology 2023-04-27

In this study, the roles of kiwifruit soluble/insoluble dietary fiber (SDF/IDF, respectively) in pasting characteristics and vitro digestibility wheat starch were explored. According to RVA rheological tests, IDF enhanced viscosity, decreased gelatinization degree granules, exacerbated retrogradation. The addition SDF high quantities could reduce level, lower system exacerbate Through determining leached amylose content conducing scanning electron microscopy, added was combined with wrapped...

10.3390/nu16050749 article EN Nutrients 2024-03-05

Previously, we determined that diallyl disulfide (DADS) from garlic oil can inhibit Pseudomonas aeruginosa PAO1 pathogenic factors by inactivating the transcription of key genes three quorum sensing (QS) systems (las, rhl, and pqs) based on effects DADS growth, virulence factor production (elastase, pyocyanin, biofilm, swarming motility), RNA (real-time q-PCR). To further investigate mechanisms underlying inhibition P. QS DADS, high-throughput proteome sequencing techniques were used to...

10.3389/fmicb.2018.03222 article EN cc-by Frontiers in Microbiology 2019-01-07

Provisioning of sufficient lipids and vitellogenin to the oocytes is an indispensable process for fecundity oviparous insects. Acute mobilization lipid reserves in insects controlled by Brummer (Bmm), orthologous human adipose triglyceride lipase (ATGL). To investigate functional roles brummer-mediated lipolysis brown planthopper, Nilaparvata lugens. RNA interference (RNAi) analyses were performed with double-stranded (dsRNA) against NlBmm adult females. Knockdown expression resulted obesity...

10.3389/fphys.2018.01535 article EN cc-by Frontiers in Physiology 2018-10-30
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