A5103261883- Traditional Chinese Medicine Analysis
- Neurological Disease Mechanisms and Treatments
- Bioactive natural compounds
- Asthma and respiratory diseases
- Inflammasome and immune disorders
- Respiratory and Cough-Related Research
- Gout, Hyperuricemia, Uric Acid
- Alcohol Consumption and Health Effects
- Acupuncture Treatment Research Studies
Chengdu University
2024
Chengdu University of Traditional Chinese Medicine
2021
Kunming Medical University
2015-2017
Mangiferin, a natural glucosyl xanthone from the leaves of Mangifera indica L., was previously shown to exert potent hypouricemic effects associated with inhibition activity xanthine dehydrogenase/oxidase. The present study aimed evaluate its uricosuric effect and possible molecular mechanisms underlying renal urate transporters responsible for reabsorption in vivo. Mangiferin (1.5–24.0 mg/kg) administered intragastrically hyperuricemic mice rats induced by intraperitoneal injection uric...
The objective of this study was to investigate the protective effect notoginsenoside R1 (NGR1) on cerebral ischemia-reperfusion injury (CIRI) in rats, and its molecular mechanism, provide new insights into diagnosis treatment CIRI. Sixty Sprague-Dawley rats were randomly divided four groups including sham-operation group (Sham), model (CIR), NGR1 (NGR1), nimodipine positive control (NDC) with 15 each. Bilateral common carotid arteries occlusion used establish rat CIRI model. area infarction...