A5070237711- Economic and Financial Impacts of Cancer
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Prostate Cancer Treatment and Research
- Cancer Genomics and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Multiple and Secondary Primary Cancers
- Renal cell carcinoma treatment
- Global Cancer Incidence and Screening
- Statistical Methods in Clinical Trials
- Advances in Oncology and Radiotherapy
- Urological Disorders and Treatments
- Colorectal Cancer Treatments and Studies
- BRCA gene mutations in cancer
- Radiopharmaceutical Chemistry and Applications
- Sperm and Testicular Function
- Prostate Cancer Diagnosis and Treatment
- Genital Health and Disease
- Palliative Care and End-of-Life Issues
- LGBTQ Health, Identity, and Policy
- Metastasis and carcinoma case studies
- Ethics in Clinical Research
- Fibroblast Growth Factor Research
Hoag Memorial Hospital Presbyterian
2022-2025
University of California, Irvine Medical Center
2021-2022
University of California, Irvine
2020-2022
UC Irvine Health
2021-2022
University of California, Davis
2018-2019
University of California Davis Medical Center
2018
Tel Aviv University
1979-2015
Tulane University
2014-2015
Cleveland Clinic
2011-2012
Bell (Canada)
1991
<h3>Importance</h3> Although several cancer drugs receive US Food and Drug Administration (FDA) approval each month, it is unclear how many of these transform the treatment landscape significantly by tumor group. Specifically, remains newly approved displace existing standard-of-care therapies for their indication vs being added to therapies. <h3>Objective</h3> To examine therapy or filling breaks in systemic treatments metastatic setting, adjuvant maintenance setting. <h3>Design, Setting,...
No AccessJournal of UrologyAdult Urology1 Jan 2013Reproductive Potential Men with Obstructive Azoospermia Undergoing Percutaneous Sperm Retrieval and Intracytoplasmic Injection According to the Cause Obstruction Sandro C. Esteves, Walter Lee, David J. Benjamin, Bill Seol, Sidney Verza, Ashok Agarwal EstevesSandro Esteves Androfert, Center for Male Reproduction, Campinas, Brazil , LeeWalter Lee Reproductive Medicine, Cleveland Clinic Foundation, Cleveland, Ohio BenjaminDavid Benjamin SeolBill...
Relapsed/refractory acute myeloid leukemia (AML) is a devastating disease with poor prognosis and represents major unmet medical need. We report on real-world academic center experience of treating 25 patients relapsed/refractory AML using venetoclax in combination decitabine or azacitidine, which not otherwise widely evaluated the current literature. Our come from large, socioeconomically geographically diverse area including majority Northern California. Most had ELN Adverse Risk (52%)...
There is a rising trend in the consumption of dietary supplements, especially among adults, with purpose improving health. While marketing campaigns tout potential health benefits using it critical to evaluate harmful effects associated these supplements as well. The majority scarce research on vitamins focuses acute or chronic toxicities use supplements. Quality still required further investigate risks long-term risk developing cancers. present review concentrates studies that have...
Urachal cancer, a rare malignancy, generally presents in the clinical setting with advanced stages of disease. Systemic treatment chemotherapy is utilized this setting. However, there remains paucity data on effectiveness immune checkpoint inhibitors or targeted therapies for urachal cancer. We analyzed genomic profile cancer order to identify potentially targetable mutations and evaluate tumor microenvironment. 42 samples were retrospectively analyzed. Our results showed that TP53, GNAS...
446 Background: There are approximately 13,400 oncologists engaged in patient care the US as of 2022. As field medical oncology becomes subspecialized not only academic but community settings, it remains unclear unknown how many practicing identify genitourinary oncologists. Methods: Using lists for top fifty hospitals per state ranked by News & World Report, we identified We then those with a primary (100%) or predominant (50% greater) areas clinical focus oncology. collected data on...
696 Background: The treatment landscape for genitourinary (GU) malignancies, including bladder, kidney, and prostate cancers, has evolved with several novel therapies approved in the past decade. importance of mental health patients cancer is being more recognized years. This study evaluates monitoring psychiatric symptoms trials leading to FDA approvals GU cancers. Methods: We comprehensively reviewed trial protocols publications FDA-approved from 2015-2024. For each therapy, we examined...
872 Background: There were 255 cancer drug approvals by the US Food and Drug Administration (FDA) between January 2020 October 2024. Although genitourinary (GU) cancers (prostate, urothelial, renal testicular) compromise some of most prevalent malignancies, it is unclear how many these intended for treatment cancers. Methods: Using list FDA approvals, we identified GU indications We collected data on tumor type, line treatment, control arm, primary endpoint(s) as studied in corresponding...
Abstract Background. Pemetrexed is a commonly used treatment for platinum-resistant advanced urothelial carcinoma (UC) based on objective response rates of 8% and 28% in two small phase II studies. To address the discrepancy reported to assess efficacy toxicity outside clinical trial setting, we performed large retrospective analysis pemetrexed use at Memorial Sloan Kettering Cancer Center. We also investigated candidate prognostic factors overall survival this setting explore whether...
Patients with coccidioidal meningitis require lifelong antifungal therapy. Cumulative toxicity and lack of efficacy salvage therapy in the treatment some patients. In a retrospective review nine patients treated isavuconazole, successful was seen three stable disease confirmed six Isavuconazole may be useful addition to therapeutic choices currently available for meningitis.