- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Antimicrobial Resistance in Staphylococcus
- Nail Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Actinomycetales infections and treatment
- Peptidase Inhibition and Analysis
- Pleural and Pulmonary Diseases
- Infectious Diseases and Mycology
- Streptococcal Infections and Treatments
- Infectious Diseases and Tuberculosis
- Clostridium difficile and Clostridium perfringens research
- Autoimmune and Inflammatory Disorders
- Bacterial Identification and Susceptibility Testing
- Viral-associated cancers and disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Bacterial Infections and Vaccines
- Virology and Viral Diseases
- Electroconvulsive Therapy Studies
- Parasitic Infections and Diagnostics
- Vascular Anomalies and Treatments
- Eosinophilic Disorders and Syndromes
- Cytomegalovirus and herpesvirus research
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
Kern Medical Center
2016-2025
University of California, Los Angeles
2015-2024
Bakersfield Heart Hospital
2024
Dignity Health
2023-2024
Memorial Hospital
2024
University of California, San Francisco
2023
University of Utah Health Care
2023
Istituto Zooprofilattico Sperimentale delle Venezie
2012-2019
VA Greater Los Angeles Healthcare System
2008
Olive View-UCLA Medical Center
2008
ABSTRACT Uropathogens other than Escherichia coli occur with greater frequency in patients risk factors for urinary tract infection (UTI). However, little is known about associations between uropathogen species and host characteristics. Three hundred nineteen urine specimens containing a balanced distribution of were selected from inpatients outpatients at university hospital clinical microbiology laboratory. Information on characteristics was retrospectively collected by chart review....
Telavancin is a fairly novel antibiotic derived from vancomycin developed to combat the constant evolutionary war against bacteria. It has achieved high clinical success in its role treating Gram-positive organisms, although like case of any other antibiotics, failure can arise. The purpose this article describe which telavancin clinically failed persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia patient while describing cause that led failure.
In the middle of a pandemic, patients with cough and fever are thought to have SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). It should be remembered that in desert southwest United States, we an ongoing epidemic coccidioidomycosis (CM). There additionally many other illnesses could confused CoV-2 or overlooked. This is case report engrafted on chronic cavitary pulmonary CM. time where coronavirus pandemic becoming rampant, demonstrate coinfection this case, importance...
Since the 1990s, influenza A viruses of H9N2 subtype have been causing infections in poultry population around globe. This is widely circulating and human cases AI sporadically reported countries where this virus endemic domestic birds. The wide circulation throughout Europe Asia along with their ability to cause direct infection mammals humans, raises public health concerns. was for first time Iran 1998 at present it poultry. study carried out evaluate exposure among workers from Fars...
Patients with coccidioidal meningitis require lifelong antifungal therapy. Cumulative toxicity and lack of efficacy salvage therapy in the treatment some patients. In a retrospective review nine patients treated isavuconazole, successful was seen three stable disease confirmed six Isavuconazole may be useful addition to therapeutic choices currently available for meningitis.
Abstract Central nervous system infection with Coccidioides spp. is fatal if untreated and complications occur even when therapy directed by experienced clinicians. We convened a panel of clinicians in the management coccidioidal meningitis to summarize current controversies provide consensus for this difficult infection.
Abstract Coccidioidomycosis is a fungal infection with range of clinical manifestations. Currently used antifungal agents exhibit variable efficacy and toxicity profiles that necessitate evaluation additional therapeutic options. Improvement was observed in the majority patients treated isavuconazole, failures only those coccidioidal meningitis.
Abstract Background Severe coccidioidomycosis presenting with respiratory failure is an uncommon manifestation of disease. Current knowledge this condition limited to case reports and small series. Methods A retrospective multicenter review patients coccidioidomycosis-associated acute distress syndrome (CA-ARDS) was conducted. It assessed clinical laboratory variables at the time presentation, reviewed treatment course, compared cohort a national database noncoccidioidomycosis ARDS....
Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving corticosteroids had a significant reduction in secondary cerebrovascular events (P .0049). Those with CM-associated (8%) may benefit from short-term corticosteroids.
Neuropsychiatric symptoms are a common complication of COVID-19, with documented both during acute COVID-19 infection (parainfectious) and persisting or developing after the resolution respiratory (postinfectious). Patients have presented variety such as anosmia, thrombotic events, seizures, cognitive attention deficits, new-onset anxiety, depression, psychosis, rarely catatonia. Etiology appears to be related disruption regular neurotransmission hypoxic injury secondary systemic...
Patients with severe coccidioidomycosis infections are often treated either amphotericin B lipid complex (ABLC) or liposomal (L-AmB). Outcome data these agents in cases currently lacking. The purpose of this study is to evaluate the efficacy and toxicity ABLC L-AmB treating coccidioidomycosis. A retrospective pre-post design was employed. Chart reviews were completed from 1 January 2005 31 December 2014 for all patients who received lipid-based B. Inclusion criteria included having a...
Hypersensitivity to triazoles is a rare occurrence and cross-reactivity between agents unknown. We present successful voriconazole challenge in patient allergic fluconazole itraconazole.A 41-year-old immunocompetent male with coccidioidomycosis developed fever, eosinophilia maculopapular rash from fluconazole. Switching itraconazole resulted worsening of the skin sloughing over 25% his body. He was given an oral-graded which he tolerated without incident.This first report lack voriconazole.
Coccidioidomycosis, a fungal infection endemic to the Southwestern United States, is challenging diagnose. The coccidioidomycosis enzyme immunoassay (EIA) test least expensive and simplest perform detect antibodies in serum. Concerns regarding falsely positive immunoglobulin (Ig) M EIA results have led questions about agreement of commercially available kits among laboratories. We sought evaluate laboratory at three laboratories using both IMMY Meridian kits. Sensitivity specificity IgM IgG...