A5043936126- Epilepsy research and treatment
- Glaucoma and retinal disorders
- Pharmacological Effects and Toxicity Studies
- Corneal surgery and disorders
- Glioma Diagnosis and Treatment
- Ophthalmology and Visual Impairment Studies
- Neuroscience and Neuropharmacology Research
- Intraocular Surgery and Lenses
- Retinal Development and Disorders
- Ocular Surface and Contact Lens
- Retinal and Macular Surgery
- Facial Trauma and Fracture Management
- Autoimmune Neurological Disorders and Treatments
- Cancer-related molecular mechanisms research
- CNS Lymphoma Diagnosis and Treatment
- Connexins and lens biology
- Global Health Workforce Issues
- Developmental Biology and Gene Regulation
- Ion channel regulation and function
- Traumatic Ocular and Foreign Body Injuries
- Neurological Disease Mechanisms and Treatments
- Attention Deficit Hyperactivity Disorder
- Congenital heart defects research
- Retinal Diseases and Treatments
- Neuroblastoma Research and Treatments
Johns Hopkins Hospital
2022-2023
Johns Hopkins University
2020-2022
Johns Hopkins Medicine
2020-2021
Massachusetts Eye and Ear Infirmary
2017-2019
Harvard University
2019
Yale University
2015-2017
Dartmouth College
2015
Abstract As the field of neuro-oncology makes headway in uncovering key oncogenic drivers pediatric glioma, role precision diagnostics and therapies continues to rapidly evolve with important implications for standard care clinical management these patients. Four studies at major academic centers were published last year outlining clinically integrated molecular profiling targeting brain tumors; all 4 demonstrated feasibility utility incorporating sequencing into children tumors, particular...
To investigate the frequency of primary versus secondary eye removal, enucleation evisceration, and characteristics outcomes patients undergoing these procedures after presenting with severe ocular trauma.Retrospective chart review to emergency department (ED) trauma necessitating or evisceration between 2010 2018.There were 92 eyes from 90 included in our study. Twenty-seven percent underwent removal (n=25, 14 enucleation, 11 evisceration), while 73% (n=67, 50 17 evisceration). The mean...
ABSTRACT Although both genetic and non‐genetic factors are known to contribute the occurrence of Attention‐Deficit Hyperactivity/Disorder (ADHD), little is about how they impact specific symptoms. We used a cross‐fostering approach with an established animal model ADHD, Spontaneously Hypertensive Rat strain (SHR), test influence genotype maternal behavior on ADHD‐related behaviors. SHRs their normo‐active relative, Wistar Kyoto rats (WKY), were cross‐fostered unfamiliar dam either same or...
To report a case of iris non-Hodgkin lymphoma initially thought to be uveitis-glaucoma-hyphema (UGH) syndrome.We reviewed the clinical, radiographic, and histopathologic findings in patient with recurrent hyphemas increased ocular pressure who eventually was found have rapidly growing mass.An 89-year-old man history cataract extraction mantle cell developed hyphema, which subsequently revealed due an mass. A biopsy that could not formally subclassified but suspicious for lymphoma. The tumor...
Clobazam, a 1,5-benzodiazepine FDA-approved in 2011, is commonly used to treat anxiety and epilepsy. It has not associated with hypothermia until very recently, case report involving two pediatric patients. Here, we the first of development an adult patient epilepsy clobazam use. A couple months after starting clobazam, started developing episodes every several weeks, temperatures ranging from 90 °F-95 °F. Normothermia was achieved Bair Hugger therapy. Thyroid-stimulating hormone cortisol...
A quality of life study comparing scleral buckle and pneumatic retinopexy for the treatment rhegmatogenous retinal detachment Angela C Gauthier, Ron Adelman Department Ophthalmology Visual Science, Yale School Medicine, New Haven, CT, USAPatients who have undergone surgical may significantly impaired visual-related life.1 Although there are many studies that compare visual outcomes anatomical success in treating detachment, inadequate data contrasting measures between these two...
To identify factors related to suboptimal refractive outcomes after toric intraocular lens implantation.A retrospective case-control chart review of 446 eyes with insertion by the same surgeon at a university hospital from 2016 2020 was conducted. Pre-operative exam findings, biometry, and one month three post-operative vision refraction were noted. Reviewed charts considered cases if uncorrected distance visual acuity (UDVA) worse than 20/40, spherical equivalent (SE) >1 diopter (D) off...
Purpose: The purpose of this study was to determine the safety and outcomes myopic laser in situ keratomileusis (LASIK) patients who were secondarily diagnosed with hypermobile Ehlers–Danlos syndrome (EDS). Methods: We conducted a case series on EDS underwent LASIK surgery. Visual acuity, manifest refraction, full dilated eye examination, biometry measurements, Scheimpflug imaging performed Wilmer outpatient clinic. Results: There 24 eyes 12 included study. All participants White women mean...
Objective: To report a case of hypothermia associated with clobazam in an adult epileptic patient. Background: Benzodiazepines usually have only mild side effects, but they been occasionally especially the elderly or very young. Clobazam, 1,5-benzodiazepine FDA approved 2011, has never this adverse effect until recently, involving two pediatric patients. Methods: Case history was obtained through clinical record review. Results: The patient is 58-year-old male developmental delay, left...
OBJECTIVE: To determine the prevalence and characteristics of seizure clusters in a prospective study. BACKGROUND: A cluster is defined as occurrence multiple seizures within short period time. Clusters may negatively impact patient’s quality life often result increased healthcare utilization. DESIGN/METHODS Subjects were categorized according to their reported frequency over year prior enrollment into one three groups: clusters, active epilepsy free. The group included subjects reporting...