Hiroshi Gotô

ORCID: 0000-0002-3982-1303
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About
Contact & Profiles
Research Areas
  • Anesthesia and Sedative Agents
  • Anesthesia and Pain Management
  • Airway Management and Intubation Techniques
  • Cervical and Thoracic Myelopathy
  • Spine and Intervertebral Disc Pathology
  • Erythrocyte Function and Pathophysiology
  • Veterinary Pharmacology and Anesthesia
  • Hemoglobin structure and function
  • Total Knee Arthroplasty Outcomes
  • Anesthesia and Neurotoxicity Research
  • Shoulder Injury and Treatment
  • Congenital Diaphragmatic Hernia Studies
  • Heart Rate Variability and Autonomic Control
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Balance, Gait, and Falls Prevention
  • Knee injuries and reconstruction techniques
  • Epilepsy research and treatment
  • Pituitary Gland Disorders and Treatments
  • Hernia repair and management
  • Gastrointestinal disorders and treatments
  • Esophageal and GI Pathology
  • Orthopaedic implants and arthroplasty
  • Spinal Fractures and Fixation Techniques
  • Neuroscience of respiration and sleep
  • Heme Oxygenase-1 and Carbon Monoxide

Tokyo Kasei University
2021

Weatherford College
2021

Suzuki (Japan)
2021

The University of Tokyo
2017-2021

Tokyo Women's Medical University
2021

Impact
2021

University of Tokyo Hospital
2021

Ome Municipal General Hospital
2016

RMIT University
2015

Tokyo Metropolitan Ohtsuka Hospital
2014

Object. Ossification of the posterior longitudinal ligament (OPLL) often progresses after surgery, and this may cause late-onset neurological deterioration. There have been few studies, however, to clarify any correlation between progression clinical outcome, partly because lack studies involving reliable reproducible methods by which detection is made possible. The authors conducted a multicenter study investigate occurrence postoperative elucidate possible risk factors in large-scale...

10.3171/spi.2005.3.1.0017 article EN Journal of Neurosurgery Spine 2005-07-01

Abstract Clinical application of artificial oxygen carriers as a substitute for blood transfusion has long been expected to solve some the problems associated with transfusion. Use delivery treatment ischemic disease by also examined. These prospective applications are, however, still in development. We have developed liposome‐encapsulated hemoglobin (LEH), developmental code TRM‐645, using technologies encapsulation concentrated (Hb) high efficiency well surface modification achieve...

10.1111/j.1525-1594.2008.00699.x article EN Artificial Organs 2009-01-23

IN 1962, Engel<sup>1</sup>first described a "cytoplasmic body" in pathologic human skeletal muscle fibers and chick embryo vitro. Since then, several reports<sup>2-5</sup>dealing with the ultrastructure of have referred to cytoplasmic body, but without detailed description. Recently, we examined patient suffering from late-onset atrophy, weakness hands, peroneal muscles, shoulder girdle. Skeletal contained numerous inclusions resembling body. This article describes various types possible...

10.1001/archneur.1970.00480210080010 article EN Archives of Neurology 1970-03-01

The combination of fentanyl and diazepam significantly decreases systemic vascular resistance blood pressure. We attempted to elucidate the reason these drugs can reduce In α-chloralose-anesthetized dogs, we investigated effects on mean arterial pressure (MAP) baroreflex control renal sympathetic nerve activity (RSNA) in both intact (Study 1) baroreflex-denervated dogs 2). Study 1 included five that received 10 μg/kg followed by 0.4 mg/kg after a 10-min interval. Five more reversed sequence....

10.1213/00000539-199307000-00009 article EN Anesthesia & Analgesia 1993-07-01

To assess the oxygen transport capacity and safety of Neo Red Cells (NRC) with enzymatic reduction system methemoglobin in vitro experimental animals. Stroma free hemoglobin (SFH) prepared without damage enzymes from outdated human red blood cells, together inositol hexaphosphate as an allosteric effector, NAD a coenzyme glucose, adenine inosine substrate was encapsulated within liposomes composed hydrogenated soy phosphatidylcholine, cholesterol, myristic acid alpha-tocopherol ratio...

10.3109/10731199709118931 article EN Artificial Cells Blood Substitutes and Biotechnology 1997-01-01

Goto, Hiroshi MD; Boozalis, Steve T. Benson, Kirk Arakawa, Kasumi MD, PhD Author Information

10.1213/00000539-198707000-00022 article EN Anesthesia & Analgesia 1987-07-01

BACKGROUND: Posture and physical function have been quantified in mature adults, but not elderly females. OBJECTIVE: To quantify standing posture measures of community-dwelling women over the age 65 years, to examin

10.3233/bmr-140498 article EN Journal of Back and Musculoskeletal Rehabilitation 2015-01-26

Abstract Background: There are only a few reports discussing the characteristics of intussusception developing in school‐age children. The these cases discussed, with reference to previous literature. Methods: present study included eight children among 143 patients treated on an inpatient basis at Nihon University Itabashi Hospital, during 11 year period from 1993 2003. remaining 135 were assigned infant group as controls. clinical compared those condition infants. Results: school age...

10.1111/j.1442-200x.2007.02308.x article EN Pediatrics International 2007-01-22

Epinephrine is reported to decrease the threshold of intravenous lidocaine-induced convulsions. However, mechanism underlying this effect not clear. Therefore, we carried out a study examine role vasopressor-induced hypertension.Fifty-six awake Wistar rats were assigned seven groups eight. All received continuous infusion lidocaine at rate 4 mg.kg-1.min-1 until generalized convulsions occurred. The control group (group C) plain lidocaine. acute hypertensive with epinephrine E),...

10.1097/00000542-199502000-00028 article EN Anesthesiology 1995-02-01

In a double-blind trial in 20 human volunteers, the duration of intradermal anesthesia with mixture bupivacaine, 0.5 mg, and Chloroprocaine, 3 was compared obtained either or alone. The produced by bupivacaine mixed 36 ± 16 (mean 1 SD) minutes, significantly less than same amount alone, 139 78 minutes. Duration Chloroprocaine 24 11 similar to plus bupivacaine. A possible explanation for these results is that competes nonspecific receptors at biophase surrounding nerve tissue.

10.1213/00000539-197909000-00003 article EN Anesthesia & Analgesia 1979-09-01

Recovery from esophageal atresia (EA) and tracheoesophageal fistula (TEF) has improved markedly over the years. But postoperative complications, however, have remained. This study evaluates recovery, preoperative, status of patients with EA/TEF.A retrospective review was undertaken in 24 EA/TEF after primary anastomosis (January 1975 through September 2003).There were no who had major cardiac anomalies or trisomy 18. In total, 17 (70.8%, group A) survived seven (29.2%, B) died. Birthweight...

10.1111/j.1442-200x.2006.02288.x article EN Pediatrics International 2006-11-22

We investigated the effect of flumazenil on intravenous (IV) lidocaine-induced convulsions with and without diazepam pretreatment in rats. Wistar rats (200-250 g) were divided into four groups seven each pretreated IV or normal saline solution at 6 min 3 before lidocaine infusion. The control group received solution; 0.2 mg/kg diazepam+flumazenil 0.1 flumazenil; flumazenil. After surgical preparation recovery from anesthesia, all a continuous infusion (15 mg/mL) rate 4 mg.kg-1.min-1 until...

10.1213/00000539-199207000-00016 article EN Anesthesia & Analgesia 1992-07-01
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