Hiroshi Kawashima

ORCID: 0000-0002-5090-7976
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About
Contact & Profiles
Research Areas
  • Congenital gastrointestinal and neural anomalies
  • Intestinal Malrotation and Obstruction Disorders
  • Esophageal and GI Pathology
  • Congenital Diaphragmatic Hernia Studies
  • Pediatric Hepatobiliary Diseases and Treatments
  • Urological Disorders and Treatments
  • Gastrointestinal disorders and treatments
  • Congenital Anomalies and Fetal Surgery
  • Tracheal and airway disorders
  • Minimally Invasive Surgical Techniques
  • Pelvic floor disorders treatments
  • Neuroblastoma Research and Treatments
  • Appendicitis Diagnosis and Management
  • Gallbladder and Bile Duct Disorders
  • Testicular diseases and treatments
  • Teratomas and Epidermoid Cysts
  • Hernia repair and management
  • Neuroendocrine Tumor Research Advances
  • Anorectal Disease Treatments and Outcomes
  • Diverticular Disease and Complications
  • Head and Neck Anomalies
  • Pediatric Urology and Nephrology Studies
  • Tumors and Oncological Cases
  • Pancreatic and Hepatic Oncology Research
  • Vascular Malformations and Hemangiomas

Saitama Children's Medical Center
2016-2025

Saitama Prefecture
2022

The University of Tokyo
2004-2017

Nihon University
2014

University of Tokyo Hospital
2012-2013

Kansai Rosai Hospital
2012

The Japanese Society of Gastroenterological Surgery
2011

Toshiba (Japan)
2006

Saitama Medical University
2005

Programmed death 1 (PD-1)/programmed ligand (PD-L1) pathway blockade has become a promising therapeutic target in adult cancers. We evaluated PD-L1 expression and tumor-infiltrating CD8+ T cells formalin-fixed, paraffin-embedded tumor specimens from 53 untreated pediatric patients with eight cancer types: neuroblastoma, extracranial malignant germ cell tumor, hepatoblastoma, germinoma, medulloblastoma, renal rhabdomyosarcoma, atypical teratoid/rhabdoid tumor. One rhabdomyosarcoma the...

10.1002/pbc.26018 article EN cc-by-nc-nd Pediatric Blood & Cancer 2016-05-02

Recently, laparoscopic percutaneous extraperitoneal closure (LPEC) has gained increased popularity for pediatric inguinal hernia repair. To improve cosmesis, we developed single incision LPEC (SILPEC). The aim of this study was to assess the safety and feasibility SILPEC compared with traditional open repair (OR). This a single-center retrospective cohort 2028 children who underwent between April 2005 August 2014. Nine hundred ninety-five patients OR 1033 SILPEC. Medical records were...

10.1007/s00464-017-5472-6 article EN cc-by Surgical Endoscopy 2017-06-08

Background: Immature retroperitoneal teratomas (RTs) are rare tumors predominantly diagnosed within the first year of life, with majority being benign. Complete surgical resection is primary treatment; however, challenges due to anatomical complexities and perioperative complications often arise, particularly in neonates. This study presents a case congenital immature RT identified at birth, where timing intervention was critically evaluated through review relevant literature. Case...

10.52783/jns.v14.1669 article EN Journal of Neonatal Surgery 2025-02-10

In order to better understand the current practice and outcomes of thoracoscopic repair esophageal atresia (EA)/tracheoesophageal fistula (TEF), a multi-institutional analysis was conducted among seven Japanese institutes.A survey sent institutes regarding surgical technique, postoperative management, EA/TEF.The operation uniformly performed via an intrapleural approach in 0-45° prone position. The TEF occluded with suture ligature four (57.1%) clips remaining three (42.9%) institutes....

10.1089/lap.2014.0250 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2015-01-16

A lymphangioma, also called a lymphatic malformation, is congenital condition that frequently occurs in young children. It classified into 3 groups depending on the size of cysts (macrocystic, microcystic, and mixed). Spontaneous regression some cases; however, characteristics patients who show have not been studied previously. Furthermore, types timing initial treatment are still controversial. Therefore, we statistically analyzed occurrence short-term spontaneous regression, patient age at...

10.1097/gox.0000000000001501 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2017-09-01

Abstract Background Biliary atresia (BA) is an intractable disease of unknown cause that develops in the neonatal period. It causes jaundice and liver damage due to destruction extrahepatic biliary tracts,. We have found heterozygous knockout mice SRY related HMG-box 17 (Sox17) gene, a master regulator stem/progenitor cells gallbladder wall, exhibit condition like BA. However, precise contribution hypoplastic wall pathogenesis hepatobiliary Sox17 embryos human BA remains unclear. Methods...

10.1038/s43856-024-00544-5 article EN cc-by Communications Medicine 2024-06-11

Abstract Background Multicenter study was undertaken to analyze the results of laparoscopic and open Kasai portoenterostomy. Methods Subjects were infants with type III biliary atresia who underwent operation ( n = 106) or 21) between January 2012 December 2015. Clinical data compared operations (2016‐0534). Propensity score matching performed reduce effect treatment selection bias. Multivariate analyses used estimate surgical approach on jaundice clearance rate native liver survival rate....

10.1002/jhbp.594 article EN Journal of Hepato-Biliary-Pancreatic Sciences 2018-11-29

The treatment of long-gap esophageal atresia remains an issue for pediatric surgeons. Many techniques treating have been proposed, but the optimal method has not established. thoracoscopic elongation technique recently developed. We previously reported a case in which two-stage repair was performed using internal traction without tearing, and we retrospectively reviewed outcomes this procedure study.Five patients underwent involving long gap or vascular ring over 5-year period.Between...

10.1089/lap.2016.0207 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2016-10-28

10.1053/j.sempedsurg.2007.06.008 article EN Seminars in Pediatric Surgery 2007-10-23
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