A5002270105- Anorectal Disease Treatments and Outcomes
- Intestinal Malrotation and Obstruction Disorders
- Monetary Policy and Economic Impact
- Pelvic floor disorders treatments
- Gastrointestinal disorders and treatments
- Congenital gastrointestinal and neural anomalies
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Gastric Cancer Management and Outcomes
- Neuroblastoma Research and Treatments
- Hernia repair and management
- Global Financial Crisis and Policies
- Market Dynamics and Volatility
- Colorectal Cancer Surgical Treatments
- Complex Systems and Time Series Analysis
- Pancreatic and Hepatic Oncology Research
- Metastasis and carcinoma case studies
- Economic theories and models
- Signaling Pathways in Disease
- Appendicitis Diagnosis and Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Diverticular Disease and Complications
- Gastroesophageal reflux and treatments
- Ovarian cancer diagnosis and treatment
- Congenital Diaphragmatic Hernia Studies
Kobe University
2010-2025
Takatsuki General Hospital
2024
Niigata University Medical and Dental Hospital
2021-2023
Jichi Medical University
2015-2022
Jichi Medical University Saitama Medical Center
2015-2022
Sanden (Japan)
2021
Niigata Prefectural Central Hospital
2021
The University of Tokyo
2017
Osaka University
2015
Nihon University
2004-2014
Abstract Bone marrow‐derived mesenchymal stem or stromal cells (MSC) have been shown to be recruited various types of tumor tissues, where they interact with promote their proliferation, survival, invasion and metastasis, depending on the type tumor. We previously that Ror2 receptor tyrosine kinase its ligand, Wnt5a, are expressed in MSC, Wnt5a‐Ror2 signaling MSC induces expression CXCL16, which, turn, promotes proliferation co–cultured MKN45 gastric cancer via CXCL16‐CXCR6 axis. However, it...
Abstract A chemically-activatable alkynyl steroid analogue probe has been synthesized for visualizing the lipid raft membrane domains by Raman microscopy. The probe, in which ring of its backbone is replaced with an group, was designed to enable activation alkyne signal through Eschenmoser-Tanabe fragmentation reaction oxidized cholesterol precursor bilayer membranes. observed form liquid-ordered raft-like on a model giant-liposome system similar manner as cholesterol, and large accumulated...
Previously, we established a pre-operative risk scoring system to predict contralateral inguinal hernia in children with unilateral hernias. The current study aimed verify the usefulness of our system.This was prospective patients undergoing repair from 2006 2009 at single institution. Gender, age initial operation, birth weight, operation side, and score were recorded. We analyzed incidence hernia, factors, system. follow-up period 36 months. used forward multiple logistic regression...
The objectives of the present study were to determine nutritional status, pancreatic function, and morphological changes remnant after tumor resection in children.The status was evaluated by patterns growth. Pancreatic function using a questionnaire, Bristol stool form chart, serum levels fasting blood glucose, hemoglobin A1c (HbA1c). Morphological computed tomography, magnetic resonance image, or cholangiopancreatography.The consisted 6 patients with (5 solid pseudopapillary tumors pancreas...
Collective invasion is an important strategy of cancers epithelial origin, including colorectal cancer ( CRC ), to infiltrate efficiently into local tissues as collective cell groups. Within the groups, cells at invasive front, called leader cells, are highly polarized and motile, thereby providing migratory traction that guides follower cells. However, its underlying mechanisms remain unclear. We have previously shown signaling emanating from receptor tyrosine kinase Ror2 can promote human...
Meconium obstruction without cystic fibrosis in low-birthweight neonates is a distinct clinical entity. We aimed to determine what therapeutic strategies work best very-low-birthweight with meconium of the small bowel under varied conditions caused by associated diseases prematurity.Medical records treated from 1998 2008 were retrospectively reviewed. Pre- and postnatal data, treatments, outcomes assessed.Nine patients perinatal complications identified. Mean gestational age birthweight 26.9...
To identify useful biomarkers by reviewing laboratory data for a predictor of the clinical course following treatment with radium-223 dichloride (Ra-223) in patients metastatic castration-resistant prostate cancer.Eighteen cancer who were administered Ra-223 at our hospital retrospectively enrolled this study. Prostate-specific antigen doubling times before and after administration evaluated as prognostic factors treated using Kaplan-Meier method Log-rank test.Four failed to complete planned...
Abstract Introduction Recent advances in the treatment for esophageal cancer have improved prognosis after esophagectomy, but they led to an increased incidence of gastric tube cancer. In most patients who underwent retrosternal reconstruction, median sternotomy is performed; it associated with a risk postoperative bleeding and osteomyelitis, pain often negatively affects respiration. Here, we report first case thoracoscopic conduit resection supine position (TRGR‐S). Materials Surgical...
Abstract Previous reports describing laparoscopic deroofing as a management modality for hepatic cyst with biliary communication remain limited. We present the case of 76-year-old woman who was monitored 4 years giant in right lobe liver. She presented to our department chief complaint abdominal distension. Moreover, imaging revealed 24-cm cyst. During deroofing, minimal bile leakage from intra-cyst wall observed, which laparoscopically closed sutures. No or recurrence observed 18 months...
Aberrant methylation of Nr4a3 exon 3 CpG island (CpGi) was initially identified during multistep mouse skin carcinogenesis. is also known as a critical gene for neuronal development. Thus, we examined the CpGi in brain tissues from 15-day embryos, newborns and 12-week-old adults found significant increase its expression development after birth. In addition, homologous region human genome frequently aberrantly methylated neuroblastoma specimens. A quantitative analysis DNA revealed that...
Abstract Background: There are only a few reports discussing the characteristics of intussusception developing in school‐age children. The these cases discussed, with reference to previous literature. Methods: present study included eight children among 143 patients treated on an inpatient basis at Nihon University Itabashi Hospital, during 11 year period from 1993 2003. remaining 135 were assigned infant group as controls. clinical compared those condition infants. Results: school age...