- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Breast Implant and Reconstruction
- Body Contouring and Surgery
- Breast Cancer Treatment Studies
- Cutaneous Melanoma Detection and Management
- Wound Healing and Treatments
- Nonmelanoma Skin Cancer Studies
- Melanoma and MAPK Pathways
- Facial Rejuvenation and Surgery Techniques
- Thyroid Cancer Diagnosis and Treatment
- Bone fractures and treatments
- Cancer and Skin Lesions
- Dermatologic Treatments and Research
- Cancer Genomics and Diagnostics
- Lymphatic System and Diseases
- Ear and Head Tumors
- Nasal Surgery and Airway Studies
- Vascular Tumors and Angiosarcomas
- Surgical Sutures and Adhesives
- Cleft Lip and Palate Research
- Skin Protection and Aging
- Radiation Dose and Imaging
- Ear Surgery and Otitis Media
- Tracheal and airway disorders
University of Sassari
2012-2025
Azienda Ospedaliero Universitaria di Sassari
2022
University of Salerno
2013-2019
Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona
2017-2018
Centre de recherche en Epidémiologie et Santé des Populations
2010-2018
Inserm
2002-2018
Université Paris-Sud
2010-2018
Karlstad Central Hospital
2018
Institut Gustave Roussy
2002-2017
Université Paris-Saclay
2017
The late health effects associated with radioiodine (131I) given as treatment for thyroid cancer are difficult to assess since the number of patients treated at each centre is limited. risk second primary malignancies (SPMs) was evaluated in a European cohort patients. A common database obtained by pooling 2-year survivors three major Swedish, Italian, and French cohorts papillary follicular time-dependent analysis using external comparison performed. study concerned 6841 patients, diagnosed...
Purpose The prevalence of BRAF, NRAS, and p16CDKN2A mutations during melanoma progression remains inconclusive. We investigated the distribution in these genes different tissues. Patients Methods In all, 291 tumor tissues from 132 patients with were screened. Paired samples primary melanomas (n = 102) synchronous or asynchronous metastases same 165) included. Tissue underwent mutation analysis (automated DNA sequencing). Secondary lesions included lymph nodes 84), skin 36), visceral 25),...
Abstract Background There is no consensus on the appropriate treatment of lymphedema. Proposed techniques include lymphaticovenous anastomosis (LVA), vascularized lymph nodes transfer (VLNT), and suction lipectomy (SL). The benefit combined procedures has also been postulated. In this prospective study, a protocol proposed as an alternative to single‐procedure strategies. Methods Between January 2016 October 2018, we enrolled patients with secondary lymphedema lower limbs, stage II‐III...
Breast cancer-related lymphedema (BCRL) affects approximately 20% of women after breast cancer therapy. Advances in treatment have increased the life expectancy; thus, prevalence BCRL will continue to rise with number survivors, hence need develop strategies prevent this condition. We provide a systematic review literature on primary prevention by prophylactic lymphatic surgery (PLS). Between June and August 2022, we conducted search PubMed, Google Scholar Cochrane. In end, total eighteen...
Abstract Background Tumescent local anesthesia (TLA) describes the practice of injecting a very dilute solution anesthetic combined with epinephrine and sodium bicarbonate into tissue until it becomes firm tense to obtain vasoconstriction. The use TLA in augmentation intramuscular gluteoplasty has never been described for implants positioning. Advantages technique include reduction blood loss through epinephrine-induced vasoconstriction hydrostatic compression from tumescent effect. We...
Body contouring surgery is increasingly requested by patients, both for aesthetic and post-bariatric purposes. There has also been a rapid increase in demand noninvasive treatments. While brachioplasty burdened numerous complications unsatisfactory scars, conventional liposuction unsuitable all nonsurgical arm remodeling performed with radiofrequency-assisted (RFAL) allows to effectively treat most of regardless the amount fat ptosis skin avoiding surgical excision.
Abstract Background Tumescent local anesthesia (TLA) involves the infusion of a saline solution containing lidocaine and epinephrine into tissues to achieve localized vasoconstriction. While use TLA in sub-glandular augmentation mammoplasty has been documented, we present modified approach for primary sub-muscular breast transgender patients based on our experience over past years. Methods Between years 2014 2021, performed 20 under conscious sedation. The tumescent consisted 25 mL 2%...
In total, 281 of the 7711 women who were initially treated for breast cancer between 1954 and 1983 at Gustave Roussy Institute developed a second malignant neoplasm (SMN) other than primary nonmelanoma skin least 1 year after treatment. We carried out nested case-control study to determine overall relationship dose radiotherapy received given anatomical site risk SMN same site. 75% cases previously by radiotherapy, as compared 73% controls. irradiated patients, median local was higher among...
Background: The thoracodorsal artery perforator flap was described mainly for partial breast reconstruction by Hamdi. purpose of this article is to describe the use pedicled total autologous without using an implant. Methods: Between January 2009 and December 2011, seven patients underwent with a flap. mean age 53 years (range, 43 62 years), body mass index 27 kg/m2 24 32 kg/m2). Results: size harvested skin paddle 23.7 × 8.8 cm2 15 7 39 14 cm2). flaps were based on one three perforators...
Background: Scalp-associated cutaneous squamous cell carcinoma (cSCC) presents formidable treatment challenges, especially when it leads to full-thickness defects involving bone. Aggressive or recurring cases often demand a multidisciplinary approach. Leveraging our surgical experience and literature review, we introduce therapeutic algorithm guide the selection of reconstruction methods, particularly for locally advanced lesions, furthermore showing synergy between surgery other therapies...
Background This investigation explores the potential impact of Negative Pressure Wound Therapy (NPWT) dressing on mommy makeover surgical wounds. The focus is optimizing healing process and post-surgical care to mitigate complications like wound dehiscence, seroma, hematoma.
Capsular contracture is a highly distressing, difficult complication after breast augmentation for both the patient and surgeon. Although capsular multifactorial process, one common denominator in successful treatment of this believed to be abatement inflammation. Leukotriene antagonists have recently emerged as effective prophylactic agents reactive airway diseases. Anecdotal reports indicated that zafirlukast (Accolate, AstraZeneca) effectively reverses contracture. A prospective study 120...
Thirty-two patients affected by SSTIs including DFIs were enrolled between 2013 and 2014. Superficial swab was obtained before after cleansing with sterile saline, ultrasonic debridement; deep tissue biopsy from ulcer base. Samples diluted 1 mL of serial 10-fold dilutions to 10−6 made 50 μL each dilution plated onto appropriate media. Bacteria identified Vitek II system. Microbial load expressed as CFU/mL. Statistical analysis performed χ2. Incidence Gram positives higher than negatives (S....