Giovanni Fadda

ORCID: 0000-0003-4422-042X
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About
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Research Areas
  • Mycobacterium research and diagnosis
  • Dental materials and restorations
  • Endodontics and Root Canal Treatments
  • Breast Cancer Treatment Studies
  • Lung Cancer Treatments and Mutations
  • Synthesis and Biological Evaluation
  • Cancer Genomics and Diagnostics
  • Dental Research and COVID-19
  • Fungal Infections and Studies
  • HIV Research and Treatment
  • HIV/AIDS drug development and treatment
  • Cytomegalovirus and herpesvirus research
  • Ovarian cancer diagnosis and treatment
  • Estrogen and related hormone effects
  • Lung Cancer Research Studies
  • Clostridium difficile and Clostridium perfringens research
  • Cancer Immunotherapy and Biomarkers
  • Ear and Head Tumors
  • Oral microbiology and periodontitis research
  • Infectious Diseases and Mycology
  • Yersinia bacterium, plague, ectoparasites research
  • HER2/EGFR in Cancer Research
  • Tuberculosis Research and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • Nonmelanoma Skin Cancer Studies

Azienda Ospedaliero Universitaria di Sassari
2001-2024

University of Sassari
1999-2024

University of Siena
2007-2014

Università Cattolica del Sacro Cuore
1999-2013

Fondazione Centro Marino Internazionale
2012

University of Florence
2012

University of Parma
2008-2009

University of the Sacred Heart
2007

Pontifícia Universidade Católica de São Paulo
2007

Università Campus Bio-Medico
2004

This in vivo study examined the contribution of remaining coronal dentin and placement a prefabricated (LP) or customized fiber post (ES) to six-year survival endodontically treated premolars. A sample 345 patients provided 6 groups 60 premolars each need endodontic treatment. Groups were classified according number walls before abutment build-up. Within group, teeth allocated one three subgroups: (A) no retention; (B) LP; (C) ES (N = 20). All protected with crown. Cox regression analysis...

10.1177/0022034512447949 article EN Journal of Dental Research 2012-06-14

Culture-independent molecular techniques such as real-time PCRs offer the potential for early diagnosis of invasive aspergillosis (IA), thereby reducing disease-associated mortality rate. PCR-based testing is presently excluded from disease-defining consensus criteria due to lack standardization and clinical validation. A single-center prospective study was conducted investigate performance commercially available MycAssay Aspergillus test detecting DNA in patients with suspicion IA. To this...

10.1128/jcm.05026-11 article EN Journal of Clinical Microbiology 2011-10-20

ABSTRACT An iCycler iQ real-time PCR assay targeting 18S rRNA Aspergillus -specific sequences was developed for the diagnosis of invasive pulmonary aspergillosis (IPA). Positive findings were obtained 18 20 (90%) bronchoalveolar lavage (BAL) fluid specimens from patients with probable or confirmed IPA and none 24 BAL samples no clinical evidence aspergillosis. These results concordant those a nested assay, which detected 90% IPA, while galactomannan ELISA revealed positivity 100% these...

10.1128/jcm.41.8.3922-3925.2003 article EN Journal of Clinical Microbiology 2003-08-01

Bacterial-derived DNA fragments (BDNAs) have been shown to be present in dialysis fluid, pass through dialyzer membranes, and induce IL-6 (IL-6) mononuclear cells. The study aimed at assessing the eventual presence of BDNAs blood hemodialysis (HD) patients if this is associated with markers chronic inflammation.Fifty-eight HD 30 controls were included study. A sample was collected from a peripheral vein central venous catheter (CVC) or arteriovenous fistula (AVF) examined for by 16S rRNA...

10.2215/cjn.03490708 article EN Clinical Journal of the American Society of Nephrology 2009-01-01

<h3>AIMS</h3> To identify and determine antibiotic susceptibility of coagulase negative staphylococci (CoNS) isolated from patients with chronic blepharitis, purulent conjunctivitis, suppurative keratitis. <h3>METHODS</h3> A retrospective review all culture positive cases keratitis between July 1995 December 1996 was performed. Cases in which CoNS were the sole isolates analysed. Species identification performed by using a commercially available standardised biochemical test system....

10.1136/bjo.83.7.771 article EN British Journal of Ophthalmology 1999-07-01

The objective of this prospective clinical trial was to investigate the influence residual coronal structure endodontically treated teeth and type cement used for luting fiber posts on four-year survival. Two groups (n = 60) were defined, depending amount dentin after abutment build-up final preparation: (1) more than 50% structure; (2) equal or less structure. Within each group, randomly divided into 2 subgroups 30) according material posts: (A) resin core material, Gradia Core; (B)...

10.1177/0022034514527970 article EN Journal of Dental Research 2014-03-19

A corneal isolate of Acanthamoeba castellanii was exposed to commercial contact lens disinfecting solutions containing hydrogen peroxide, benzalkonium chloride, polyaminopropyl biguanide, polyquaternium 1, and chlorhexidine-thimerosal. The minimum trophozoite amebicidal concentration exposure times required kill trophozoites cysts were determined. Solutions peroxide or chlorhexidine-thimerosal active against both cysts. chloride-based solution effective only trophozoites. biguanide 1...

10.1128/aac.39.7.1596 article EN Antimicrobial Agents and Chemotherapy 1995-07-01

Background: Scalp-associated cutaneous squamous cell carcinoma (cSCC) presents formidable treatment challenges, especially when it leads to full-thickness defects involving bone. Aggressive or recurring cases often demand a multidisciplinary approach. Leveraging our surgical experience and literature review, we introduce therapeutic algorithm guide the selection of reconstruction methods, particularly for locally advanced lesions, furthermore showing synergy between surgery other therapies...

10.3390/jcm13061581 article EN Journal of Clinical Medicine 2024-03-10

Assessment of the epidermal growth factor receptor (EGFR) mutational status has become crucial in recent years molecular classification patients with lung cancer. The impact type and quantity malignant cells neoplastic specimen on quality mutation analysis remains to be elucidated, only empirical sporadic data are available. aim present study was investigate tissue content EGFR among adenocarcinoma. A total 515 histologically‑confirmed disease were included study. Formalin‑fixed paraffin...

10.3892/mmr.2015.3347 article EN cc-by-nc Molecular Medicine Reports 2015-02-12

We determined prospectively during a 12-month period the incidence, clinical characteristics and outcome of Yersinia enterocolitica infection in 144 thalassemic patients (mean age, 12.8 years) compared them with 100 controls 12.1 years). Symptomatic Y. occurred 14 (10%) 2 (2%) (P = 0.017). Of 5 (36%) had septicemia 9 (64%) focal (enteritis 8 tonsillitis 1). One control patient acute enteritis other tonsillitis. All isolates from these belonged to pathogenic phenotypes enterocolitica. Pending...

10.1097/00006454-199507000-00005 article EN The Pediatric Infectious Disease Journal 1995-07-01

<h3>Abstract</h3> Uterine tumors resembling ovarian sex cord (UTROSCT) are distinguished into two separate groups: endometrial stromal with cord-like elements (Group I), which have an unfavorable prognosis; and UTROSCT proper (group II), more than 40% differentiation less component, biologically aggressive the of other group. We report case a young woman treated by minimally invasive hysteroscopic surgery. This is one few cases reported in literature that been managed conservatively.

10.1111/igc.0b013e3181a417b4 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2009-05-01
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