An advanced mode of drug delivery system has been developed to overcome the major drawbacks associated with conventional systems. This review gives a detailed idea about nanoemulsion system. Nanoemulsions are nano-sized emulsions, which manufactured for improving active pharmaceutical ingredients. These thermodynamically stable isotropic in two immiscible liquids mixed form single phase by means an emulsifying agent, i.e., surfactant and co-surfactant. The droplet size falls typically range...

A novel sulfate-reducing bacterium isolated from fuel-contaminated subsurface soil, strain PRTOL1, mineralizes toluene as the sole electron donor and carbon source under strictly anaerobic conditions. The mineralization of 80% to CO2 was demonstrated in experiments with [ring-U-14C]toluene; 15% converted biomass nonvolatile metabolic by-products, primarily former. observed stoichiometric ratio moles sulfate consumed per mole consistent theoretical for coupled reduction hydrogen sulfide....

The extent of surgery for well-differentiated thyroid cancer remains controversial. purpose this study was to evaluate the type resection, age, T classification, nodal status, tumor size, and year diagnosis overall survival (OS) cause-specific (CSS) using a large database.Using Surveillance, Epidemiology, End Results (SEER) database, 23,605 subjects were identified with papillary or follicular between 1983 2002. OS CSS estimated, outcomes local excision, lobectomy, near-total thyroidectomy,...

A rapidly-growing facultatively aerobic bacterium that transforms tetrachloroethene (PCE) via trichloroethene (TCE) to cis-1,2-dichloroethene (cis-1,2-DCE) at high rates in a defined medium was isolated from contaminated site. Metabolic characterization, cellular fatty acid analysis, and partial sequence analysis of 16S rRNA showed the new isolate, strain MS-1, has characteristics matching those members family Enterobacteriaceae. Strain MS-1 can oxidize about 58 substrates including many...

Several five membered ring systems, e.g., triazole, oxadiazole dithiazole and thiadiazole with three heteroatoms at symmetrical or asymmetrical positions have been studied because of their interesting pharmacological properties. In this article our emphasis is on synthetic development activity the triazole moiety which exhibit a broad spectrum such as antifungal, antibacterial, anti-inflammatory anticancer etc. Triazoles increased ability to treat many fungal infections, for example,...

Objective Pre‐eclampsia ( PE ) is associated with maternal cardiac remodelling and biventricular diastolic dysfunction. Preterm alone can also be severe left ventricular hypertrophy systolic The aim of this study was to assess whether the cardiovascular profile at mid‐gestation in nulliparous normotensive women differs destined develop preterm versus those who will term. Design Prospective study. Setting Tertiary referral university centre. Population A total 269 women, including 152...

Over the past decades, cancer is major cause of incidence death increasing every day. Different forms tumor therapy including radiotherapy and chemotherapy are used to treat cancer. However, hyperthermia technique that neglects use chemicals or harmful radiations. The elevated body temperature can damage cancerous cells with minimum injury normal cells. Successful method in combination radiation and/or provided patient which proved be beneficial patients. In this review, different studies...

Recent advances in the field of pharmaceutical biotechnology have led to formulation many protein and peptide-based drugs for therapeutic clinical application. The route administration has a significant impact on outcome drug. needle syringe is well established choice peptide delivery which some drawback related patient such as pain, cost, sterility etc. Thus, noninvasive routes were minor importance parts drug past assumed added these include nasal, ophthalmic, buccal, vaginal, transdermal...

Cancer patients have a shorter life expectancy because of metastasis, which is the dynamic chain events that leads to spread tumour cells distant places inside body. Cancer's development, spread, and treatment all involve fluid mechanics in some way. their associated components take advantage body's many systems as means dissemination throughout body colonisation organs. Cancerous tissues rely on blood supply for oxygen nutrition, metastasis other organs, medication delivery. cells' ability...

Abstract The Nipah virus, a highly pathogenic zoonotic pathogen, has once again surfaced in the state of Kerala, India, with recent cases reported 2023. This article delves into epidemiological details these cases, shedding light on two fatalities that occurred September 2023 and August as well suspected have undergone testing. known for its severe neurological respiratory disease manifestations, remains formidable health threat due to lack specific treatments or vaccines. government’s...

ABSTRACT Heavy metal resistance by bacteria is a topic of much importance to the bioremediation contaminated soils and sediments. We report here isolation highly cadmium-resistant Klebsiella planticola strain, Cd-1, from reducing salt marsh The strain grows in up 15 mM CdCl 2 under wide range NaCl concentrations at acidic or neutral pH. In growth medium amended with thiosulfate, it precipitated significant amounts cadmium sulfide (CdS), as confirmed x-absorption spectroscopy. comparison...

Abstract Background Constant's Shoulder Scale is a validated and widely applied instrument for assessment of shoulder function. We used this to assess which treatment demographic variables contribute dysfunction after neck dissection in head cancer patients. Methods A convenience sample 54 patients with 64 dissections minimum follow‐up 11 months were evaluated. Thirty‐two accessory nerve–sparing modified radical (MRND) 32 selective (SND) performed. Multivariable regression analysis was...