- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Infectious Aortic and Vascular Conditions
- Lymphoma Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Lung Cancer Treatments and Mutations
- Infective Endocarditis Diagnosis and Management
- Radiopharmaceutical Chemistry and Applications
- Medical Imaging and Pathology Studies
- Advanced MRI Techniques and Applications
- Dementia and Cognitive Impairment Research
- Orthopedic Infections and Treatments
- Hematological disorders and diagnostics
- Esophageal Cancer Research and Treatment
- Advanced Radiotherapy Techniques
- Functional Brain Connectivity Studies
- Sarcoma Diagnosis and Treatment
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Cancer Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Lung Cancer Diagnosis and Treatment
- Aortic aneurysm repair treatments
- Histiocytic Disorders and Treatments
- Cardiovascular Function and Risk Factors
Na Homolce Hospital
2008-2019
Charles University
1989-2006
Czech Academy of Sciences, Institute of Biophysics
1989-1990
ObjectiveTo report on the short- and long-term outcomes of patients with primary infected aortic aneurysm (IAA) treated by stent graft (SG) in two centers.Material methodOver a period 15 years, 32 IAA underwent endovascular treatment. None had undergone previous surgery. The causal relationship was gastrointestinal infection 9 (28%), diagnostic/therapeutic procedures/resuscitation 6 (19%), wound after surgeries 5 (16%), urinary 4 (13%), urology or gastroenterology procedures 3 (9%),...
Abstract The prognosis of patients with Langerhans cell histiocytosis (LCH) involving the central nervous system (CNS) is generally poor, despite reports clinical responses to chemotherapy, surgery, and radiation. We report on a patient 20‐year history relapsing multisystem LCH who developed progressive neuropsychiatric symptoms, including diplopia, ataxia, mental deterioration. There was regression lesions in brain stem cerebellum following chemotherapy cladribine (2‐CdA) as evidenced by...
Bacterial infection of the aorta is a life threatening condition calling for timely diagnostics and therapy. In short communication presented here, authors offer case report on patient 70 years age with aneurysm descending caused by salmonella. The advantages new diagnostic hybrid modality are demonstrated also possibility using it in course long-term monitoring patients.
BACKGROUND: Low-grade gliomas (LGG) of the brain have an uncertain prognosis, as many them show continuous growth or upgrade over course time. We retrospectively investigated role positron emission tomography with 3’-deoxy-3’-[18F]fluorothymidine (FLT-PET) in prediction overall survival and event free patients untreated LGG. No such information is yet available literature. MATERIAL AND METHODS: Forty-one previously LGG underwent 55 FLT-PET investigations during their follow-up because...
Background When applying the PET Response Criteria in Solid Tumors protocol, a threshold value based on standardized uptake corrected to lean body mass (SUL) liver parenchyma, or blood pool, is used: metabolically specify measurable lesion; calculate metabolic tumor volume (mTV) and its product total lesion glycolysis (TLG); as limit for response measurement. The problem with using changes glucose metabolism marker therapy reproducibility test–retest examinations. Therefore, before...
SUMMARY When a patient is examined by positron emission tomography (PET), radiotracer dose amount (activity) has to be determined. However, the rules for activity correction according patients’ weight used nowadays do not correspond with practical experience. Very high image quality achieved slim patients, whereas noisy images are produced obese patients. There opportunity modify rule aim equalize within broad spectrum of patients and diminish radiation risk special importance children. We...
We investigated whether the reproducibility of standard visual reporting (STD method) in flutemetamol (FMM) PET can be improved using a newly introduced method that uses grey matter edges derived from perfusion phase (GM-EDGE method).Two-phase FMM was performed 121 patients with mild cognitive impairment. Five nuclear medicine physicians blindly and independently evaluated all late-phase scans, initially employing STD later GM-EDGE method. A five-point scale used to express degree amyloid...
The aim of the analysis was to assess accuracy various FDG-PET/CT parameters in staging lymph nodes after neoadjuvant chemotherapy. In this prospective study, 74 patients with adenocarcinoma esophageal–gastric junction were examined by course their chemotherapy given before surgical treatment. Data from final examinations compared histology specimens (gold standard). calculated for four parameters: (1) hypermetabolic nodes, (2) large (3) large-and-medium and (4) or nodes. patients, a total...
The combination of positron emission tomography and computed (PET/CT) offers metabolic mapping in addition to anatomic information the primary lesion, nodal distant metastases patients with head neck tumors, may be therefore beneficial for radiotherapy planning.The aim our study was evaluate benefits combined PET CT imaging staging target volume delineation this group patients.Fifty three (40 men 13 women) confirmed advanced, inoperable or non-radically operated cancer were assessed based on...
A 25-year-old man was admitted for abdominal pain and bicytopenia (anaemia + thrombocytopenia) in November 2003. Trephine biopsy revealed an aplastic marrow with cellularity less than 5% (panel 5). diagnostic plan included positron emission tomography-computed tomography (PET-CT) to exclude malignancy before starting immunosuppression. In the week preceding PET-CT, patient developed neutropenic sepsis severe gastro-intestinal bleeding. He treated antibiotics granulocyte colony-stimulating...