A5050469350- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Brain Metastases and Treatment
- Vascular Malformations Diagnosis and Treatment
- Blood transfusion and management
- Advanced Radiotherapy Techniques
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Neurofibromatosis and Schwannoma Cases
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Pituitary Gland Disorders and Treatments
- Sepsis Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Intracranial Aneurysms: Treatment and Complications
- Radiopharmaceutical Chemistry and Applications
- Medical Imaging Techniques and Applications
- Ocular Oncology and Treatments
- Blood donation and transfusion practices
- Management of metastatic bone disease
- Surgical Sutures and Adhesives
- Human Health and Disease
- Healthcare Systems and Public Health
- Blood Pressure and Hypertension Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Radiation Dose and Imaging
Na Homolce Hospital
2012-2025
Prince Charles Hospital
2013-2022
The University of Queensland
2013-2022
Australian Red Cross Lifeblood
2013-2022
KU Leuven
2020
Oxford University Press (United Kingdom)
2018
Cleveland Clinic
2018
University of Pittsburgh
2018
Neurological Surgery
2018
Taipei Veterans General Hospital
2018
Meningioma is the most frequent benign tumor treated with Gamma Knife surgery (GKS); however, assessment of its efficacy and safety in slow-growing tumors an ongoing process, requiring analysis long-term results.Three hundred sixty-eight patients harboring 400 meningiomas between 1992 1999 at Na Homolce Hospital were evaluated. The median patient age was 57 years (range 18-84 years). volume 4.4 cm3 0.11-44.9 cm3). margin dose to 50% isodose line 12.55 Gy 6.5-24 Gy). Descriptive performed 331...
Although relevant information exists regarding the chance of obliterating arteriovenous malformations (AVMs) using radiosurgery, overall cure after gamma knife radiosurgery is usually only extrapolated from a portion all monitored patients. This and risks involved in including repeat treatment when necessary defined population treated patients, were analyzed our study.Between October 1992 June 2000, was performed on 330 patients with AVMs. The volume AVM nidus ranged 0.15 to 28.6 cm (median,...
Partial or complete dislodgement of intravascular catheters remains a significant problem in hospitals despite current securement methods. Cyanoacrylate tissue adhesives (TA) are currently used to close skin wounds as an alternative sutures. These have high mechanical strength and can remain situ for several days. This study investigated vitro use TAs securing (IVC). We compared two interaction with IVC material, comparing glues methods terms their ability prevent inhibit microbial growth....
Glomus tumors usually display indolent behavior, and the effectiveness of radiation in stopping their growth can be assessed after long-term follow-up. Currently only midterm results radiosurgery are available, so authors included patients treated by Gamma Knife at least 10 years ago this study to obtain a perspective results.During period from 1992 2003, was used treat 46 with glomus tumors. The age ranged 21 79 (median 56 years). primary treatment 17 (37%). Open surgery preceded 46% cases,...
Object. The authors conducted a study to record more detailed information about the natural course and factors predictive of outcome following gamma knife surgery (GKS) for cavernous hemangiomas. Methods. One hundred twelve patients with brain hemangiomas underwent GKS between 1993 2000. median prescription dose was 16 Gy. seven were followed 48 months (range 6–114 months). rebleeding rate 1.6%, which is not significantly different that prior radiosurgery (2%). An increase in volume observed...
Background Extra corporeal membrane oxygenation (ECMO) is a complex rescue therapy used to provide cardiac and/or respiratory support for critically ill patients who have failed maximal conventional medical management. ECMO based on modified cardiopulmonary bypass (CPB) circuit, and can up‐to several months. It be in veno venous configuration isolated failure, (VV‐ECMO), or arterial (VA‐ECMO) where necessary +/‐ failure. The circuit consists of five main components: large bore cannulae...
Sepsis is a multi-system syndrome that remains the leading cause of mortality and critical illness worldwide, with hemodynamic support being one cornerstones acute management sepsis. We used an ovine model endotoxemic shock to determine if 0.9% saline resuscitation contributes lung inflammation injury in respiratory distress syndrome, which common complication sepsis, investigated potential role matrix metalloproteinases this process.Endotoxemic was induced sheep by administration escalating...
Major adverse cardiovascular events are closely associated with 24-hour blood pressure (BP). We determined outcome-driven thresholds for mean arterial (MAP), a BP index estimated by oscillometric devices. assessed the association of major MAP, systolic (SBP), and diastolic (DBP) in population-based cohort (n=11 596). Statistics included multivariable Cox regression generalized R
Hypertension is the predominant modifiable cardiovascular risk factor. This cohort study assessed association of with percentage time that ambulatory blood pressure (ABP) within target range (PTTR) proposed by 2024 European Society Cardiology (ESC) guidelines for (BP) management. In a person-level meta-analysis 14 230 individuals enrolled in population cohorts, systolic and diastolic ABPs were combined to assess 24-h, daytime, nighttime PTTR thresholds non-elevated ABP set at <115/65,...
We have treated 14 patients with glomus tumor during the 4 years (of 1993 to 1997) using Leksell Gamma Knife radiosurgery. The male: female ratio was 1:3.7, and mean age 48.6 (range 22-75 years). volume 5.5 cm3 0.7-11.3 cm3). maximum dose 37.4 Gy 20-44 Gy). margin 19.4 10-25 In 3 patients, infrabasal spread of could not be delineated on peroperative stereotactic CT scans. As a result, this portion in 2 at second stage MRI. Follow-up 11 ranged from 6 42 months (mean 20.5 months). Hearing...
Background The growing awareness of transfusion‐associated morbidity and mortality necessitates investigations into the underlying mechanisms. Small animals have been dominant transfusion model but associated limitations. This study aimed to develop a comprehensive large animal (ovine) encompassing: blood collection, processing storage, compatibility testing right through post‐transfusion outcomes. Materials methods Two units were collected from each 12 adult male M erino sheep processed 24...
There are limited data regarding outcomes for patients with gastrointestinal (GI) primaries and brain metastases treated stereotactic radiosurgery (SRS).To examine clinical after SRS from GI evaluate potential prognostic factors.The International Radiosurgery Research Foundation centers were queried managed SRS. Primary local control (LC) overall survival (OS). Kaplan-Meier analysis was used univariate (UVA) of factors. Factors significant on UVA evaluated a Cox multivariate proportional...
Extracorporeal membrane oxygenation (ECMO) is a life-saving modality used in the management of cardiopulmonary failure that refractory to conventional medical and surgical therapies. The major problems clinicians face are bleeding clotting, which can occur simultaneously. To discern impact pulmonary injury ECMO on host's haemostatic response, we developed an ovine model smoke-induced acute lung (S-ALI) ECMO. aims this study were determine if circuit itself altered haemostasis was augmented...