- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Sodium Intake and Health
- Heart Rate Variability and Autonomic Control
- Nutrition and Health Studies
- Cardiovascular Function and Risk Factors
- Hormonal Regulation and Hypertension
- Cardiovascular Disease and Adiposity
- Nutritional Studies and Diet
- Nutrition, Genetics, and Disease
- Cardiac Imaging and Diagnostics
- Pregnancy and preeclampsia studies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular and exercise physiology
- Cardiac Arrhythmias and Treatments
- Menopause: Health Impacts and Treatments
- Hormonal and reproductive studies
- Liver Disease Diagnosis and Treatment
- Climate Change and Health Impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Economics and Policy
- COVID-19 Clinical Research Studies
- Hemodynamic Monitoring and Therapy
- Renal and Vascular Pathologies
- Vitamin D Research Studies
Jagiellonian University
2016-2025
Institute of Cardiology
2019-2024
Krakow Cardiovascular Research Institute
2023
TU Dresden
2021
Chief Inspectorate of Environmental Protection
2021
Cardinal Stefan Wyszyński University in Warsaw
2019
Medical University of Silesia
2019
KU Leuven
2003-2016
University of Milano-Bicocca
2016
IRCCS Istituto Auxologico Italiano
2016
Extrapolations from observational studies and short-term intervention trials suggest that population-wide moderation of salt intake might reduce cardiovascular events.To assess whether 24-hour urinary sodium excretion predicts blood pressure (BP) health outcomes.Prospective population study, involving 3681 participants without disease (CVD) who are members families were randomly enrolled in the Flemish Study on Genes, Environment, Health Outcomes (1985-2004) or European Project Genes...
To analyze sex-specific relative and absolute risks associated with blood pressure (BP), we performed conventional 24-hour ambulatory BP measurements in 9357 subjects (mean age, 52.8 years; 47% women) recruited from 11 populations. We computed standardized multivariable-adjusted hazard ratios for associations between outcome systolic BP. During a course of 11.2 years (median), 1245 participants died, 472 cardiovascular causes. The number fatal combined nonfatal events was 1080, 525, 458...
Hypertensive disorders in pregnancy (HDP), remain the leading cause of adverse maternal, fetal, and neonatal outcomes. Epidemiological factors, comorbidities, assisted reproduction techniques, placental disorders, genetic predisposition determine burden disease. The pathophysiological substrate clinical presentation HDP are multifarious. latter lack well designed trials field explain absence consensus on disease management among relevant international societies. Thus, usual is largely...
The coronavirus disease 19 (COVID-19) recently became one of the leading causes death worldwide, similar to cardiovascular (CVD). Coexisting CVD may influence prognosis patients with COVID-19.We analyzed impact and use drugs on in-hospital course mortality retrospectively studied data for consecutive admitted our hospital, COVID-19 between March 6th October 15th, 2020.1729 (median interquartile range age 63 [50-75] years; women 48.8%) were included. Overall, was 12.9%. most prevalent...
1. Nadciśnienie tętnicze. Raport NFZ 2022r. https://www.nfz.gov.pl/aktualn... (access: 2024.07.11). Google Scholar
Abstract Background The left atrium plays a crucial role in managing ventricular filling and contractility through its functions as reservoir, conduit, boost pump. Consequently, the interaction between atrium(LA), ventricle(LV), arterial system appears critical determinant of comprehensive cardiovascular performance. Non-dipping profile blood pressure(BP) 24-hr monitoring(ABPM) is associated with increased mortality morbidity, including atrial fibrillation stroke. Objective We aimed to...
Major adverse cardiovascular events are closely associated with 24-hour blood pressure (BP). We determined outcome-driven thresholds for mean arterial (MAP), a BP index estimated by oscillometric devices. assessed the association of major MAP, systolic (SBP), and diastolic (DBP) in population-based cohort (n=11 596). Statistics included multivariable Cox regression generalized R
In a cross-sectional analysis of case-control study in 2015, we revealed the association between increased arterial stiffness (pulse wave velocity) and aircraft noise exposure. June 2020, evaluated long-term effects, impact sudden decline exposure during coronavirus disease 2019 (COVID-19) lockdown, on blood pressure pulse velocity, comparing 74 participants exposed to day-evening-night level >60 dB 75 unexposed individuals. During 5-year follow-up, prevalence hypertension (42% versus 59%,...
Sex differences in blood pressure control are recognized. We systematically investigated sex specific components of ambulatory (ABP), including variability, day-night changes, morning surge, and hypertension types.We analyzed ABPs 52 911 participants (45.6% male, 54.4% female, 37.0% treated for hypertension) visiting 860 Italian community pharmacies. ABP levels patterns were evaluated the whole group 4 risk groups (antihypertensive-treated patients, patients with diabetes, dyslipidemia, or...
In the European Project On Genes in Hypertension (EPOGH), we investigated 3 populations to what extent left ventricular mass (LVM) was associated with genetic variation angiotensin II receptors type 1 (AGTR1 A1166C) and 2 (AGTR2 G1675A) while accounting for possible gene-gene interactions angiotensin-converting enzyme (ACE D/I) angiotensinogen (AGT -532C/T) polymorphisms.We randomly recruited 221 nuclear families (384 parents, 431 offspring) Cracow (Poland), Novosibirsk (Russia), Mirano...
Data on the role of androgens as potential mediators increasing cardiovascular risk in women at midlife are controversial. The aim study was to analyze relationship free testosterone (FT) and sex hormone binding globulin (SHBG) with blood pressure subclinical organ damage metabolic syndrome (MS) middle aged hypertensive women.One hundred fifty-two newly diagnosed arterial hypertension were included study. In all subjects measurements performed well echocardiographic examination left...
Abstract Background COVID-19 has affected older persons the most. The propensity to have severe or die of infection was especially prevalent among subjects with multimorbidity, frailty and sarcopenia. aim our study check which simple clinical biomarkers, including assessment muscle frailty, would associate survival length hospital stay in patients COVID-19. An additional report influence chronic diseases, medication use, signs symptoms on aforementioned outcome measures. Methods CRACoV a...
The significant difference in central and peripheral blood pressure (BP) values has only recently been widely recognized. Ambulatory BP monitoring shown to have advantages over office measurements because ambulatory can provide important information not available when is measured. aim of this study was assess the 24-hour systolic (CSP) profile, CSP short-term variability, amplification profile.The group comprised 50 hypertensive subjects normotensive subjects. All participants underwent...
A P E R Management of hypertension in pregnancy 757 to 10% pregnancies the United States and Europe.Women with chronic HT (1%-5% general population) have a higher risk PE than women without pre existing (17%-25% vs 3%-5%, respectively).Furthermore, 7% 20% poor BP control (excluding those PE).Significantly elevated is di rect threat maternal fetal health life.According World Health Organization (WHO), its complications are among leading causes mortality developed countries (approx.16%)....
We investigated the heritability and familial aggregation of various indexes arterial stiffness wave reflection we partitioned phenotypic correlation between these traits into shared genetic environmental components.Using a family-based population sample, recruited 204 parents (mean age, 51.7 years) 290 offspring (29.4 from in Cracow, Poland (62 families), Hechtel-Eksel, Belgium (36), Pilsen, Czech Republic (50). measured peripheral pulse pressure (PPp) sphygmomanometrically at brachial...
<b><i>Background:</i></b> Advances in anti-lymphoma therapy prolong overall survival, making late adverse effects, like doxorubicin-related cardiotoxicity, an even more important clinical issue. The effectiveness of cardioprotective strategies with close monitoring, angiotensin-converting enzyme inhibitors and/or β-blockers as well liposomal doxorubicin are still unconfirmed practice. <b><i>Methods:</i></b> This study evaluated the role a...
Pressure-induced left ventricular hypertrophy is one of the mechanisms responsible for an impaired coronary vasodilating capacity leading to myocardial ischemia and angina. The aim study was investigate perfusion using cardiovascular magnetic resonance in patients with arterial hypertension a history chest pain normal angiography, estimate influence on parameters perfusion.The included 102 (mean age 55.4 +/- 7.7 years) well controlled 12 healthy volunteers. In 96 patients, first-pass both at...
Background: The relationship between hypertension and oxidative stress remains unexplained. Nevertheless, it is well establishedthat reactive oxygen species have an influence on the arterial wall, endothelial function therefore determine blood pressure. Aim: evaluation of selected markers in hypertensive patients assessment structure function. We also aimed to investigate whether remodelling arteries, their structural functional changes independent or related hypertension. Methods:...