A5087219231- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Nutrition and Health Studies
- Heart Rate Variability and Autonomic Control
- Obstructive Sleep Apnea Research
- Pregnancy and preeclampsia studies
- Retinal Imaging and Analysis
- Sodium Intake and Health
- Nutritional Studies and Diet
- Cardiovascular Function and Risk Factors
- Genetic and Kidney Cyst Diseases
- Cardiovascular Disease and Adiposity
- Management and Organizational Practices
- Neuroscience of respiration and sleep
- Nutrition, Genetics, and Disease
- Human Health and Disease
- Hormonal Regulation and Hypertension
- Global Health Care Issues
- Metabolomics and Mass Spectrometry Studies
- Cardiovascular Health and Risk Factors
- Renal Diseases and Glomerulopathies
- Pharmacology and Obesity Treatment
- Biomedical Text Mining and Ontologies
- Liver Disease Diagnosis and Treatment
- Topic Modeling
Gdańsk Medical University
2016-2025
Jan Długosz University
2022
Institute of Cardiology
2019
Cardinal Stefan Wyszyński University in Warsaw
2019
GTx (United States)
2018
Animal and human data indicate pathological afferent signaling emanating from the carotid body that drives sympathetically mediated elevations in blood pressure conditions of hypertension. This first-in-man, proof-of-principle study tested safety feasibility unilateral resection 15 patients with drug-resistant The procedure proved to be safe feasible. Overall, no change was found. However, 8 showed significant reductions ambulatory coinciding decreases sympathetic activity. may a novel...
In the medical field, text annotation involves categorizing clinical and biomedical texts with specific categories, enhancing organization interpretation of large volumes unstructured data. This process is crucial for developing tools such as speech recognition systems, which help professionals reduce their paperwork. It addresses a significant cause burnout reported by up to 60% staff. However, annotating in languages other than English poses unique challenges necessitates using advanced...
A P E R Management of hypertension in pregnancy 757 to 10% pregnancies the United States and Europe.Women with chronic HT (1%-5% general population) have a higher risk PE than women without pre existing (17%-25% vs 3%-5%, respectively).Furthermore, 7% 20% poor BP control (excluding those PE).Significantly elevated is di rect threat maternal fetal health life.According World Health Organization (WHO), its complications are among leading causes mortality developed countries (approx.16%)....
Arterial stiffening is a hallmark of early vascular aging (EVA) syndrome and an independent predictor cardiovascular morbidity mortality. In this case-control study we sought to identify plasma metabolites associated with EVA in the setting hypertension. An untargeted metabolomic approach was used age-, BMI-, sex-matched groups (n = 79) non-EVA 73) individuals After raw data processing filtration, 497 putative compounds were characterized, out which 4 identified as lysophosphaditylcholines...
Resistant hypertension (RH) affects about 15-20% of treated hypertensive patients worldwide. RH increases the risk cardiovascular events such as myocardial infarction and stroke by 50%. The pathological mechanisms underlying resistance to treatment are still poorly understood.The main goal this pilot study was determine compare plasma metabolomic profiles in resistant non-resistant patients.We applied untargeted profiling samples collected from 69 subjects with 81 controlled hypertension. To...
Introduction. Cardiovascular disease (CVD) is a major cause of mortality, and has risk factors, which can be treated by lifestyle changes or medications. Abdominal obesity been identified as the second strongest factor for myocardial infarction. Objectives. To assess frequency abdominal its relationship with hypertension (HT) CVD in patients Poland, to compare frequencies adiposity, HT between Poland North-West Europe Region, obtained IDEA study. Methods. In general practitioners included...
Purpose: In the course of hypertension, left ventricular hypertrophy and diastolic dysfunction develop very often may progress toward heart failure. The aim study was to analyze relationship between abnormalities retinal microcirculation cardiac damage defined as and/or dysfunction.Materials methods: comprised 88 patients with essential hypertension. group divided into two subgroups: hypertensives without (n = 55) 33). Control 32 normotensive subjects. Scanning laser Doppler flowmetry used...
Background: Although the presence of sub-clinical left ventricular diastolic dysfunction (LVDD) increases cardiovascular risk, current ESH/ESC guidelines do not include this condition in list target organ damage or risk charts dedicated to hypertensive population. Several conditions may predict LVDD occurrence, however, clustering these factors with hypertension makes relationship less clear. Therefore, aim study was evaluate both occurrence and severity a large cohort treated...
ADDITIONAL INFORMATION This article has been co‑published in Kardiologia Polska (doi:10.33963/KP.14904), Arterial Hypertension (doi:10.5603/AH.a2019.0011), and Ginekologia (doi:10.5603/GP.2019.0074). The articles Polska, Hypertension, are identical except for minor stylistic spelling differences keeping with each journal’s style. Any citation can be used when citing this article.
Endothelial cell migration and proliferation play an important role in the growth development of new blood vessels endothelium healing. This process occurs response to injury, inflammation immune reactions. Dysfunction may a significant progression cardiovascular disease related sleep-disordered breathing. The aim our study was evaluate chemo-attractant activity serum from obstructive sleep apnea (OSA) normal subjects on coronary artery endothelial migration.We studied 12 severe OSA...
Arterial hypertension in majority of cases is the result a poor lifestyle. The table salt intake level has changed over centuries. In populations characterized by low daily consumption, was rarity and cardiovascular diseases were much less common. More more food sold processed form, thus containing large amounts salt. amount delivered with significantly exceeds actual body's needs. Limitation should apply to both prevention as well treatment people suffering from hypertension. High sodium...
The purpose of this article is to evaluate the utility ultrasound in identifying carotid bodies (CBs) patients with drug-resistant arterial hypertension.We enrolled 13 hypertension into a trial for surgical CB excision. CT angiography (CTA) and Doppler (DUS) cervical arteries were performed before surgery. CBs identified blind manner at both CTA DUS. defined as ovoid avidly enhancing structures inferomedial aspect bifurcation. At DUS, solid bifurcation.CBs 12 (23/26 sides) using 11 (18/26...
Introduction: Arterial stiffness is recognized as an intermediate phenotype and predictor of cardiovascular disease. complex in origin with contributions from lifestyle genetic factors. However, the association between single nucleotide polymorphisms (SNPs) arterial remains unclear. Objective: The aim to assess whether a multilocus risk score (GRS), composed selected SNPs linked traits outcomes, associated patients hypertension. Design methods: This study included 730 participants derived...
The aim of this study was to examine the relationship between orthostatic hypotension, cardiovascular drug intake and mortality in a very elderly community-dwelling population (>80 years age).In 2013-2014, 224 (71 M, 31.7%) 80-year-old individuals from one primary care practice were invited participate. Basic clinical information gathered blood pressure (BP) measurements performed while sitting after 1 3 min standing position on 209 patients. followed till December 2016.Orthostatic...
Objective. The aim of the present study was to compare effectiveness Systemic COronary Risk Evaluation (SCORE) charts and European Society Hypertension/European Cardiology (ESH/ESC) hypertension guidelines for identifying high-risk hypertensive patients. Methods. data on patients collected using Polish Hypertension Registry. We enrolled 636 (357 females 279 males, mean age 54.4 ± 7.9 years) from centres in Poland. Results. Only 3.5% subjects had no additional risk factors. Thirty-six per...
Introduction. Arterial hypertension (HT) affects 10.4 million adult Poles, and the blood pressure (BP) control rate is only 26%. Beyond any doubt, high results in cardiovascular (CV) target organ damage, which markedly influences national healthcare programs. Childhood introduced prophylaxis offers opportunities to decrease incident HT delay or even eliminate its consequences. Therefore we have decided study level of knowledge on CV disease (CVD) among random 1st 2nd grade school students...
When stimulated, carotid bodies (CBs) activate sympathetic activity causing hypertension. In hypertensive animals, CBs generate aberrant tone and their resection lowered blood pressure (McBryde et al. 2013. Nat.Communs 4, 2395). this first prospective proof of concept study our primary outcome was safety feasibility unilateral (u) CB in drug resistant patients; as a secondary we measured over 12 month period. 15 participants with office (OBP) 179±7/106±4 mmHg on 5.7±0.3 anti‐hypertensive...
BackgroundInaccurate blood pressure classification results in inappropriate treatment. We tested if machine learning (ML), using routine clinical data, can serve as a reliable alternative to Ambulatory Blood Pressure Monitoring (ABPM) classifying status.MethodsThis study employed multi-centre approach involving three derivation cohorts from Glasgow, Gdańsk, and Birmingham, fourth independent evaluation cohort. ML models were trained office BP, ABPM, clinical, laboratory, demographic...