A5008332494- Dialysis and Renal Disease Management
- Venous Thromboembolism Diagnosis and Management
- Blood Coagulation and Thrombosis Mechanisms
- Parathyroid Disorders and Treatments
- Bone health and treatments
- Renal Diseases and Glomerulopathies
- Bone Metabolism and Diseases
- Atrial Fibrillation Management and Outcomes
- Blood Pressure and Hypertension Studies
- Chronic Kidney Disease and Diabetes
- Polyomavirus and related diseases
- Biomarkers in Disease Mechanisms
- Renal Transplantation Outcomes and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
- Erythropoietin and Anemia Treatment
- Liver Disease and Transplantation
- Bone health and osteoporosis research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- TGF-β signaling in diseases
- Dermatological and Skeletal Disorders
- Biomedical Research and Pathophysiology
- Genetic Syndromes and Imprinting
- Potassium and Related Disorders
- Hemodynamic Monitoring and Therapy
- Sarcoidosis and Beryllium Toxicity Research
Medical University of Białystok
2015-2024
University Clinical Hospital In Bialystok
2017
St. Paul's Hospital
2012
This is the first report on epidemiology of biopsy-proven kidney diseases in Poland.The Polish Registry Renal Biopsies has collected information all (n = 9394) native renal biopsies performed Poland from 2009 to 2014. Patients' clinical data at time biopsy, and histopathological diagnoses were used for epidemiological clinicopathologic analysis.There was a gradual increase number per million people (PMP) year 2009-14, starting 36 PMP 44 A considerable variability between provinces mean...
To characterize its dose-response relationship, BI 655064 (an anti-CD40 monoclonal antibody) was tested as an add-on to mycophenolate and glucocorticoids in patients with active lupus nephritis (LN).A total of 121 were randomized (2:1:1:2) receive placebo or 120, 180, 240 mg received a weekly loading dose for 3 weeks followed by dosing every 2 the 120 180 groups, group. The primary endpoint complete renal response (CRR) at week 52. Secondary endpoints included CRR 26.A relationship 52 not...
<i>Background/Aim:</i> Recently emerging evidence suggests that oxidative stress (SOX) may participate in atherogenesis. The aim of the present study was to establish whether enhanced SOX, involving endothelial injury, activation coagulation, and inflammatory reaction, could be implicated atherosclerotic diseases haemodialysis (HD) patients. <i>Methods:</i> Markers cytokines, were measured plasma HD patients with without cardiovascular disease (CVD), healthy controls...
The aims of the study were to determine oral health-related quality life (OHRQoL) in chronic hemodialysis (HD) patients and estimate which scale describing OHRQoL, Oral Health Impact Profile (OHIP-14) or Geriatric/General Assessment Index (GOHAI), was more useful this particular group.This a cross-sectional conducted by means census survey. Polish versions OHIP-14 GOHAI used assess OHRQoL. examination included decayed, missing filled teeth (DMF-T) Index; Hygiene simplified; Plaque Gingival...
Background. Increased plasma soluble von Willebrand factor antigen (vWF : Ag) level, a marker of vascular endothelial cell dysfunction, is strong predictor atherosclerotic cardiovascular disease (CVD) in the general population. We studied cross‐sectional associations between vWF Ag prevalence CVD, and related factors including pre‐dialysis arterial blood pressure (BP) some markers inflammation maintenance haemodialysis (HD) patients.
Heparin inhibits prothrombotic tissue factor (TF) and releases its inhibitor, pathway inhibitor (TFPI), from the endothelium, but repeated administration of heparin depletes vascular stores TFPI. We studied anticoagulant effects unfractionated (UFH) vs low-molecular-weight enoxaparin-used for thrice-weekly maintenance haemodialysis (HD)-on plasma levels total TF TFPI on those an activated coagulation marker prothrombin fragment 1+2 (PF 1+2).Twenty-five patients dialysed using a single...
In the modern era, organ transplantation has become an important means of treating certain diseases. Although it is widespread and medically accepted, controversies still exist.The aim this study was to evaluate attitudes toward among medical students.The anonymous survey conducted 273 students (from departments medicine, dentistry, nursing, physiotherapy). The questionnaire self-designed contained 15 dichotomous questions.Among students, 99.6% accepted as a therapeutic method. Live-donor by...
COVID-19 has severely affected the population of patients with end stage renal disease. Current data have proved a two-dose vaccination schedule against SARS-CoV-2 to be effective among dialyzed patients. There are limited on longevity and modulating factors humoral response after vaccination. We performed prospective longitudinal cohort study determine vaccine. The included 191 adult hemodialysis peritoneal dialysis. All participants had been vaccinated three doses, either BNT162b2...
Patients receiving maintenance hemodialysis (HD) present with hemostatic abnormalities, which may be aggravated by comorbid conditions, especially liver disease. The factors that influence plasma levels of thrombomodulin (TM), an initiator the anticoagulant protein C pathway, and those tissue factor (TF), triggers extrinsic coagulation were assessed. In 63 HD patients, TM TF higher than in healthy controls. bivariate analysis, positively correlated TM, both directly associated presence viral...
Background and aims. Heparin modulates function of vascular endothelial cells. We studied the effects unfractionated heparin (UFH) versus low-molecular-weight (LMWH), enoxaparin, used as anticoagulants during hemodialysis (HD) on plasma levels circulating endothelium-derived molecules: thrombomodulin (TM), von Willebrand factor (vWF), plasminogen activator inhibitor-1 (PAI-1), cell surface adhesion molecules (E-selectin), intercellular molecule-1 (ICAM-1), prothrombin fragment 1+2 (PF 1+2)....