A5067452102- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Pituitary Gland Disorders and Treatments
- Neurofibromatosis and Schwannoma Cases
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological disorders and treatments
- Brain Metastases and Treatment
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Head and Neck Surgical Oncology
- Neuroscience of respiration and sleep
- Pain Management and Treatment
- Advanced Radiotherapy Techniques
- Spine and Intervertebral Disc Pathology
- Cardiac Arrest and Resuscitation
- Voice and Speech Disorders
- Traumatic Brain Injury Research
- Epilepsy research and treatment
- Adrenal and Paraganglionic Tumors
- Pain Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Parasitic infections in humans and animals
- Kawasaki Disease and Coronary Complications
Sylvester Comprehensive Cancer Center
2023-2025
University of Miami
2023-2025
University of Pittsburgh Medical Center
2025
University of Pittsburgh
2025
Universidade Presbiteriana Mackenzie
2024
Neurological Surgery
2023-2024
Hospital São Vicente
2015-2023
Jackson Memorial Hospital
2023
NYU Langone Health
2023
Universidade de São Paulo
2017-2023
OBJECTIVE Stereotactic radiosurgery (SRS) is used for the treatment of residual/recurrent nonfunctional pituitary adenoma (NFPA). The aim this study was to evaluate factors related long-term tumor control and delayed endocrinopathies following SRS. METHODS This retrospective, multicenter included patients with recurrent/residual NFPA treated single-fraction SRS; they were then divided into two arms. first arm at least 5 years radiographic follow-up all local progression. second...
INTRODUCTION: Stereotactic radiosurgery (SRS) is used to treat residual and recurrent nonfunctioning pituitary adenomas (NFPA). Hypopituitarism the most common complication with increasing rates over time. We present largest multicentric cohort evaluating outcomes after for NFPA. METHODS: Twelve centers contributed retrospective data on 869 patients treated SRS between 1992 2022. Tumor progression was defined as a volumetric increase of =20% from baseline. New-onset hypopituitarism...
Abstract Purpose The study evaluates rapid linear accelerator (Linac) single isocenter stereotactic radiosurgery (SRS) with Hyperarc for large target numbers. We compared to Gamma Knife (GK), which suffers from long treatment times and investigated causes of differences. Methods Linac SRS GK plans patients receiving 18 Gy the gross tumor volume (GTV) were evaluated mean brain dose 12 or more (V12 Gy) as toxicity correlates. Further investigations included patient‐based simulations 1–33...
Abstract BACKGROUND Adductor spasmodic dysphonia (SD) is a dystonia of the vocal folds causing difficulty with speech. The current standard care repeated botulinum toxin injections to weaken adductor muscles. We sought ameliorate underlying neurological cause SD novel therapy—deep brain stimulation (DBS). OBJECTIVE To assess safety DBS in through phase I trial, and quantify magnitude any benefit. METHODS Six patients had left ventral intermediate nucleus (Vim) thalamic were randomized 3 mo...
Abstract Background Stereotactic radiosurgery (SRS) is used to treat recurrent or residual nonfunctioning pituitary neuroendocrine tumors (NFPA). The objective of the study was assess imaging and development new hormone deficiency. Methods Patients treated with single-session SRS for a NFPA were included in this retrospective, multicenter study. Tumor control dysfunction evaluated using Cox analysis Kaplan–Meier curves. Results A total 869 patients (male 476 [54.8%], median age at 52.5 years...
Stereotactic radiosurgery (SRS) represents an effective treatment for nonfunctioning pituitary adenomas (NFPAs). However, no data have yet been published regarding results of SRS on NFPAs after multiple previous resections.
Background. As the survival of preterm infants has increased significantly, germinal matrix hemorrhage (GMH) become an important public health issue. Nevertheless, treatment strategies for direct neuronal injury are still scarce. The present study aims to analyze neuroprotective properties cannabidiol in hemorrhage. Methods. 112 Wistar rat pups (P7) were submitted experimental collagenase induced model GMH. Inflammatory response and death analyzed both at perilesional area as distant...
Spinal cord stimulation (SCS) is a cost-effective option for treating refractory persistent spinal pain syndrome type-2 (PSPS-2). For patients with extensive spine instrumentation including the thoraco-lumbar junction, percutaneous placement of SCS leads usually not an being paddle typically implanted anterograde. Paddle lead will be particularly challenging in more complex cases when covers targeted level. To overcome this barrier, we studied using retrograde approach to reach sweet spot,...
The cerebral proliferative angiopathy (CPA) is an uncommon vascular malformation of the brain, representing approximately 3.4% arteriovenous (AVM) cases, with complex morphology and poorly understood origin. Thus, we present case a woman patient aged 27 years, who performed magnetic resonance imaging (MRI) brain because headache. Extensive was identified right frontoparietal, presence tissue mixed vessel. CPA multiple feeder arteries, absence nidus slowing flow into venous system, confirming...
Background Hemorrhagic events can result in significant neurological damage, and identifying effective strategies for neuroprotection is crucial. Several studies have directed their attention to the alterations perilesional parenchymal tissue. These investigations sought modify ischemic metabolic changes by utilizing potential neuroprotective agents develop that effectively mitigate secondary neuronal damage. By gaining a deeper understanding of its mechanisms efficacy, Spirulina platensis...
Paracoccidioidomycosis is the most prevalent endemic mycosis in Latin America, with a great incidence Brazil. Although common disease, its medullary form rare. We present case report of paracoccidioidomycosis presenting subacute, progressive, spinal cord symptoms, and multiple expansive lesions into cervical thoracic cord. The patient was treated itraconazole showed good clinical radiologic recovery upon six months follow-up.
Introdução: O processo clinoide anterior pode apresentar variações anatômicas entre os indivíduos, até mesmo com alterações no indivíduo (entre lados), principalmente relacionado à formação de ponte óssea ele e o médio posterior. reconhecimento do forame clinocarotídeo é importante tratamento aneurismas segmento oftálmico da artéria carótida interna, uma vez que a necessidade realizar clinoidectomia proceder-se lesão inadvertida das estruturas vasculares. Objetivo: Revisar incidência...
Introdução: A ínsula apresenta anatomia complexa. escolha de corredores transsilviano ou transcortical para ressecção gliomas insulares permanece controversa, e as principais preocupações são a lesão vascular durante dissecção transilviana o comprometimento funcional no acesso transcortical.
 Objetivo: Revisar da comparar se há diferença entre extensão ressecção, morbimortalidade pós-operatória sobrevida 2 abordagens.
 Método: Revisão feita colhendo informações publicadas em...
Introdução: O processo clinoide anterior pode apresentar variações anatômicas entre os indivíduos, até mesmo com alterações no indivíduo (entre lados), principalmente relacionado à formação de ponte óssea ele e o médio posterior. reconhecimento do forame clinocarotídeo é importante tratamento aneurismas segmento oftálmico da artéria carótida interna, uma vez que a necessidade realizar clinoidectomia proceder-se lesão inadvertida das estruturas vasculares. Objetivo: Revisar incidência...
Introdução: A ínsula apresenta anatomia complexa. escolha de corredores transsilviano ou transcortical para ressecção gliomas insulares permanece controversa, e as principais preocupações são a lesão vascular durante dissecção transilviana o comprometimento funcional no acesso transcortical. Objetivo: Revisar da comparar se há diferença entre extensão ressecção, morbimortalidade pós-operatória sobrevida 2 abordagens. Método: Revisão feita colhendo informações publicadas em plataformas...